Panama Tours & Cruises in 2025

Start this Panama tour by exploring the highlands of Boquete near the Costa Rica border. Enjoy hiking through cloud forests or whitewater rafting on the Chiriqui. End your Panama travels with a couple days around Boca Chica, snorkeling in turquoise waters and soaking in the sun.

This 8-day getaway combines the first half of our popular Costa Rica tour, Beaches and Rainforest, with the clear blue waters of Panama's idyllic Bocas del Toro Archipelego. Enjoy the riotous rapids of Costa Rica's Pacuare River and three nights at Selva Bananito Lodge surrounded by wild …

Over 29% of Panama's landscape includes 15 national parks, forest reserves, and 10 wildlife sanctuaries - this itinerary is designed to visit some of the country's most celebrated. Begin your Panama travel journey with a cruise of the "8th wonder of the world", the Panama Canal, …

This Adventure Life exclusive 9-day tour travels from Costa Rica to Panama on an activity-packed exploration of Central America's Caribbean coast. From Selva Bananito Lodge in Costa Rica, you will be able to explore the wild rainforest, zipline through the canopy, and ride the rapids of the …

This 8-day Central America adventure cruise departs from Balboa, Panama, to Puntarenas, Costa Rica. The waters of San Jose Island are considered to be among the best deep-sea fishing grounds in the world due to their abundance of tropical game species. Then, spend a few days at sea exploring …

The San Blas Islands of Holandes Cayes, Panama City's Old Quarter, and the Darién National Park are highlights of Le Bellot's journey in Central America. Proceed to Fuente Amador and start your exploration of the Panama Canal. In Costa Rica, you may encounter sloths, the noisy howler …

Embark on an 11-day expedition cruise from Colon to Puntarenas aboard the Le Bellot. Visit San Lorenzo’s Fort, an extraordinary fortress safeguarding transatlantic trade. Next, explore the San Blas Islands, home to the Kuna people and their vibrant craft of molas. Cross the legendary Panama …

Join the National Geographic Quest on this 8-day expedition to Costa Rica and the Panama Canal. Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in …

Immerse in the coastal landscapes of Costa Rica and Panama on this 12-day cruise aboard Greg Mortimer with travel photographer Richard I'Anson. Costa Rica stands as one of the world's most biodiverse regions, offering opportunities to explore lush tropical rainforests with a remarkable …

Join Star Clipper on this 8-day cruise from Puerto Caldera, Costa Rica, to Balboa, Panama. Set sail through the Tortugas, regarded as the most beautiful island in Costa Rica. Then visit the small, busy town of Quepos, which serves as the gateway to the Manuel Antonio National Park. Discover Golfo …

Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac …

Set sail on a 9-day adventure aboard the SH Vega, exploring the natural and cultural wonders of Costa Rica and Panama. Discover vibrant biodiversity at the Biomuseo or visit the historic districts of Panamá Viejo and Casco Viejo in Fuerte Amador, the gateway to the Panama Canal. Explore the …

This 8-day Central America adventure cruise departs from Puerto Caldera. The waters of San Jose Island are considered to be among the best deep-sea fishing grounds in the world due to their abundance of tropical game species. Then, spend a few days at sea exploring islands and participating in Star …

Embark on an 11-day cruise aboard the SH Vega from Panama City to Belize. Start in Fuerte Amador, exploring Panama City’s historic sites before cruising the iconic Panama Canal. Navigate its 48-mile waterway, passing through locks and Gatun Lake. Experience Bocas del Toro’s pristine …