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Top Panama Trips & Tours in November 2025

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Discover Panama in November 2025 on one of these 21 tours hand-selected by the travel experts at Adventure Life. Explore the best of Panama City, Panama Canal, Bocas del Toro, San Blas Islands, and Cartagena during November 2025 as you enjoy land tours, wildlife viewing, snorkeling, small ship cruises, and ziplining. Prices for trips in November 2025 range from $1,880 to $11,662 for a vacation of 7 to 15 days. Choose any of the below 21 itineraries in November 2025 and customize it when you contact one of Adventure Life's expert Panama trip planners.
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    • Panama
Clear blue water of the Caribbean
$2,202
EXPLORE

Panama's Parks and Beaches

9 Day Itinerary
  • Visit ruins of Old Panama
  • Explore the Gailard Cut
  • Pass the Bridge of the Americas
  • Explore mountains and rural life
Starts / Ends:
Panama City / Panama City
Activities:
Archaeological Site Visits, Snorkeling, Village Visits, Wilderness Lodge Exploration
Activity Level:
Relaxed
Experience the richness of Panama's National Parks and Beaches in a 9-day adventure, from the historic ruins of Old Panama and colonial charm in Casco Antiguo to the iconic Miraflores Locks of the Panama Canal. Sail through the Canal, witness live ship transits, and explore the Amador Causeway. …
Tour Details
0
$2,461
EXPLORE

Panama Adventure

8 Day Itinerary
  • Hike through tropical forest
  • Take a coffee tour in Boquete
  • Explore the Golf of Chiriqui
  • Snorkel, kayak or hike
Starts / Ends:
Panama City / Crowne Plaza Panama Airport
Activities:
Snorkeling, Whitewater Rafting, Wildlife Viewing, Ziplining
Activity Level:
Easy Active
Start this Panama tour by exploring the highlands of Boquete near the Costa Rica border. Enjoy hiking through cloud forests or whitewater rafting on the Chiriqui. End your Panama travels with a couple days around Boca Chica, snorkeling in turquoise waters and soaking in the sun.
Tour Details
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A local fisherman pulls his boat ashore at sunset in Costa Rica
$2,402
EXPLORE

Caribbean Adventure - Bocas Town

8 Day Itinerary
  • Raft down the Pacuare River
  • Hike deep into the jungle
  • Snorkel the marine-rich coral reef
  • Tour Panama's vibrant capital city
Activities:
Horseback Riding, Rainforest Exploration, Snorkeling, Urban Exploration, Whitewater Rafting, Wilderness Lodge Exploration, Wildlife Viewing, Ziplining
Activity Level:
Easy Active
This 8-day getaway combines the first half of our popular Costa Rica tour, Beaches and Rainforest, with the clear blue waters of Panama's idyllic Bocas del Toro Archipelego. Enjoy the riotous rapids of Costa Rica's Pacuare River and three nights at Selva Bananito Lodge surrounded by wild …
Tour Details
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A jungle river in the rainforest
$1,880
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activities:
Rainforest Exploration, Village Visits, Wildlife Viewing, Ziplining
Activity Level:
Relaxed
Over 29% of Panama's landscape includes 15 national parks, forest reserves, and 10 wildlife sanctuaries - this itinerary is designed to visit some of the country's most celebrated. Begin your Panama travel journey with a cruise of the "8th wonder of the world", the Panama Canal, …
Tour Details
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$6,459
EXPLORE

Luxury Panama Escape

9 Day Itinerary
  • Mangrove kayaking in Bocas del Toro
  • Explore optional excursions
  • Tour Panama's vibrant capital city
  • Visit Panama La Vieja
Starts / Ends:
Panama City / Panama City
Activity Level:
Relaxed
Discover Panama with our 9-day itinerary! Immerse yourself in the allure of Boquete's charming town, indulge in the unique experiences at Nayara Bocas del Toro, unwind on pristine beaches, and culminate your journey with a captivating Panama City tour.
Tour Details
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Tranquilo Bay indeed...
$3,891
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities:
Hiking, Land, Rainforest Exploration, Snorkeling, Whitewater Rafting, Wildlife Viewing, Zip Line
Activity Level:
Easy Active
This Adventure Life exclusive 9-day tour travels from Costa Rica to Panama on an activity-packed exploration of Central America's Caribbean coast. From Selva Bananito Lodge in Costa Rica, you will be able to explore the wild rainforest, zipline through the canopy, and ride the rapids of the …
Tour Details
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Transitioning the Panama Canal
$323
EXPLORE

Panama Canal Full Transit

1 Day Itinerary
  • See the Panama City skyline
  • Learn the history of the canal
Activities:
Land Exploration, Small Ship Cruises
Activity Level:
Relaxed
On a guided tour of the Panama Canal, your boat will ascend and descend 26 meters in three separate chambers. The Gaillard Cut is a major tourist attraction because it was carved through the Continental Divide and is rich in history and natural beauty. Continue on to Gatun Lake and the Gatun Locks, …
Tour Details
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Miraflores Locks - Panama Canal
$276
EXPLORE

Panama Canal Partial Transit

  • Transit through Miraflores Locks
  • Learn the history of the canal
Activities:
Expedition Cruises, Land
Activity Level:
Relaxed
Tour Details
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Cathedral of Casco Viejo
$301
EXPLORE

Explore Panama City

  • Tour the ruins of Panama La Vieja
  • Watch a transit of the Panama Canal
Activities:
Land, Urban Exploration
Activity Level:
Relaxed
Tour Details
0
Capuchin monkey
$271
EXPLORE

Barro Colorado Island Tour

1 Day Itinerary
Activities:
Land, Wildlife Viewing
Activity Level:
Easy Active
Tour Details
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El Valle de Anton Valley
$343
EXPLORE

El Valle de Anton

1 Day Itinerary
Activities:
Land, Local Market, Wildlife Viewing, Zip Line
Activity Level:
Moderate
Tour Details
0
$278
EXPLORE

Embera Drua Community Visit

1 Day Itinerary
  • Discover traditional music & dance
  • Try traditional body painting
Activities:
Land, Village Visit
Activity Level:
Relaxed
Tour Details
0
Zapatilla Cay, Panama
$154
EXPLORE

Dolphin Bay and Zapatilla Island Snorkeling

Activities:
Beach Time, Land, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Tour Details
0
Traditional folklore dance of Panama
$139
EXPLORE

Las Tinajas Folklore Dinner Show

  • Sample Panamanian fare
  • Enjoy a telling of Panama folklore
Activities:
Land
Activity Level:
Relaxed
Tour Details
0
Trekking through Corcovado National Park in Costa Rica.
$7,238
EXPLORE

Costa Rica and the Panama Canal

San Jose - Panama - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Variable
Join the National Geographic Quest on this 8-day expedition to Costa Rica and the Panama Canal. Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in …
Cruise Details
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An old fort of Panama
$820
EXPLORE

Portobelo Extension

4 Day Itinerary
  • Snorkel in the bay of Portobelo
  • Visit Aguas Clara Visitor Center
  • Explore Gatun Lake busy waterway
  • Visit UNESCO Portobelo Forts
Starts / Ends:
Panama City / Panama City
Activities:
Archaeological Site Visits, Snorkeling
Activity Level:
Easy Active
Choose our Portobelo Extension to add to your captivating Panama adventure and explore its best kept secrets. From the contrasting views of Gatun Lake to the historic San Lorenzo Fort and a coastal snorkeling experience near Portobelo's bay, this extension rounds up your journey. Immerse …
Tour Details
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Zapatilla Cay, Panama
$6,741
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac …
Cruise Details
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Boats Moored to the Quay at Bridgetown Harbour
$3,830
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
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