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Top Panama Tours & Cruises in 2025

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Boats Moored to the Quay at Bridgetown Harbour
$3,830
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Gatun Lock of the Panama Canal
$3,830
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,540
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Star Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Panama City's Bridge of the Americas
$11,675
EXPLORE

Once through the Panama Canal

Panama to Costa RIca - 11 Day Itinerary aboard Sea Cloud Spirit
  • Cruise through the Panama Canal
  • Encounter islands & national parks
  • Discover Palo Verde National Park
  • Spot Coatis, jaguars and birds
Starts / Ends:
Colon / Puntarenas
Activities:
Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day cruise through the historic Panama Canal, start in Panama City and experience a dinner cruise through the iconic Panama Canal, exploring Gatúnsee's unique islands like Barro Colorado in the rainforest. Sail through the canal's 12 lock basins, showcasing its …
Cruise Details
0
Gaze at the balconies overlooking the breathtaking cathedral in Cartagena, Colombia
$8,565
EXPLORE

Just Drifting Along

Willemstad - Panama - 9 Day Itinerary aboard Sea Cloud Spirit
  • Explore Willemstad's harbor
  • Discover Oranjestad’s culture
  • Sail San Blas Archipelago
  • Stroll Aruba’s pastel streets
Starts / Ends:
Willemstad / Colon
Activities:
Archaeological Site Visits, Small Ship Sailing, Snorkeling
Activity Level:
Variable
Embark on a 9-day cruise aboard the Sea Cloud Spirit. Journey through the vibrant ABC islands, starting in Curacao with its UNESCO-listed capital, Willemstad, known for its "Little Amsterdam" charm. Explore Oranjestad, Aruba, where colorful houses and unique landscapes create its distinct …
Cruise Details
0
Look for unique birds and other wildlife in the rain forest!
$11,675
EXPLORE

Natural Wonders, Engineering Marvels

Puntarenas - Panama City - 11 Day Itinerary aboard Sea Cloud Spirit
  • Explore Nicoya Peninsula beaches
  • Discover Pearl Islands Discover Pea
  • Visit Manuel Antonio Park's
  • Sail through the Panama Canal
Starts / Ends:
Puntarenas / Colon
Activities:
Rainforest Exploration
Activity Level:
Variable
Embark on an 11-day cruise from Puntarenas to Panama City, unveiling "Pura Vida" spirit. Explore Puntarenas' cultural tapestry, venture to Puerto Jiménez's pristine jungles, and discover Marina Flamingo's luxury. Sail the Pacific, unwind at Playa Panama, and navigate …
Cruise Details
0
Starfish on the beach
$140
EXPLORE

Bird Island and Starfish Beach

Activities:
Land, Wildlife Viewing
Activity Level:
Relaxed
Tour Details
0
19-25 of 25 Results
TrustScore 4.8 | 377 reviews
TrustScore 4.8 of 5
total score
Based on 377 reviews on
review score
6 hours ago
Jessica was wonderful! She made every effort to ensure our trip was just what we wanted.
Celine Krafft
review score
6 hours ago
Erin was easy to work with and very helpful. She was patient and helped us figure out the adventure tour we were hoping for in Belize. Can’t wait to go on this trip!
Sam Wedll
review score
1 day ago
Jason has gone above and beyond. We have so much appreciation for him!
Jackie Smedley
review score
1 day ago
My travel planner, Jeff, who is on top of his field (based on travel industry awards), is a highly professional, very effective and, at the same time, personally nice individual. What was also critical to me is that he has a first hand experience traveling in the region that I am going to. On top of that, the customer relations director, Sarah, has personally followed up to make sure I'm happy.
alex shaykis
review score
2 days ago
Very well organiced. Great communication Easy to handle website for required docs to file . Pleasant Experience
Nancy Kaierle

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