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Our Panama Trips & Vacation Packages

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    • Panama
from $9,230
EXPLORE

Secrets of Central America

Colón - Puntarenas - 11 Day Itinerary aboard Le Champlain
  • Discover National Parks
  • Sail through the Panama Canal
  • Encounter with Emberas tribe
  • Visit San Blas archipelago
Starts / Ends
Puerto Caldera / Colon
Activity Level
Variable
Join this 11-day Secrets of Central America cruise and explore Panama and Costa Rica, starting at San Lorenzo’s Fort and traveling from the Atlantic to the Pacific. Visit the San Blas Islands, the Pearl Islands, Darien National Park, and cross the Panama Canal. Meet local communities, and discover the biodiversity of Rio Esquinas and Curú Nature Reserve.
Cruise Details
0
Trekking through Corcovado National Park in Costa Rica.
from $7,315
EXPLORE

Costa Rica and the Panama Canal

San Jose - Panama - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities
Horseback Riding
Activity Level
Variable
Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
0
Ruins at the Fortress of Santiago
from $820
EXPLORE

Portobelo Extension

4 Day Itinerary
  • Snorkel in the bay of Portobelo
  • Visit Aguas Clara Visitor Center
  • Explore Gatun Lake busy waterway
  • Visit UNESCO Portobelo Forts
Starts / Ends
Panama City / Panama City
Activity Level
Easy Active
Discover Panama's allure with a day exploring Aguas Clara, San Lorenzo Fort, and Portobelo's historic port. Snorkel along picturesque bays and witness colonial charm, designated a UNESCO Patrimony for Humanity.
Tour Details
0
Crossing a stream on Osa Peninsula
from $11,295
EXPLORE

Costa Rica & Panama Canal

Costa Rica - Colombia - 12 Day Itinerary aboard Greg Mortimer
  • Explore Costa Rica's wildlife
  • Discover vibrant bird species
  • Learn about the Emberá tribe
  • Cross the Panama Canal
  • Visit Curú National Wildlife Refuge
Starts / Ends
San Jose / Colon
Activities
Stand Up Paddle Boarding, Photography Seminars, Scuba Diving, Whale Watching
Activity Level
Variable
Embark on a 12-day Costa Rica & Panama Canal Cruise with travel photographer Richard I'Anson. Explore Costa Rica's rainforests, and Panama's coral reefs, connect with the Emberá tribe, and delve into Panama Canal's history.
Cruise Details
0
Costa Rica Toucan Bird
from $1,930
EXPLORE

Costa Rica to Panama

Puerto Caldera - Balboa - 8 Day Itinerary aboard Star Clipper
  • Explore Puerto Caldera’s coast
  • Relax on Isla Tortuga’s beaches
  • Experience Golfito’s rich history
  • Snorkel in Golfo de Chiriqui’s
Starts / Ends
Puerto Caldera / Balboa
Activities
Kayaking, Ziplining, Rainforest Exploration
Activity Level
Variable
Set sail on an 8-day cruise aboard the Star Clipper, starting in Puerto Caldera, Costa Rica. Explore stunning beaches, vibrant marine parks, and rich history before concluding your adventure in Balboa, Panama.
Cruise Details
0
Zapatilla Cay, Panama
from $6,741
Save 20%
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends
Panama City / Cartagena
Activity Level
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, San Bernardo Archipelago, and more.
Cruise Details
0
Explore beautiful Costa Rica
from $1,960
EXPLORE

Costa Rica & Panama

Puerto Caldera Roundtrip - 8 Day Itinerary aboard Star Clipper
  • Discover Quepos's authentic charm
  • Experience Golfito's allure
  • Swim Bahia Potrero's calm waters
  • Marvel at Arenal's majestic volcano
Starts / Ends
Puerto Caldera / Puerto Caldera
Activity Level
Variable
Set sail on an 8-day cruise aboard the Star Clipper through Costa Rica and Panama, exploring lush rainforests, pristine beaches, and vibrant marine life. Highlights include Manuel Antonio, Coiba Island, and Isla Tortuga’s turquoise waters.
Cruise Details
0
Ruins at the Fortress of Santiago
from $4,840
EXPLORE

Natural Sanctuaries & Heritage of the Caribbean

Willemstad - Colon - 8 Day Itinerary aboard Le Champlain
  • See sites in Cartagena & Willemstad
  • Explore Santa Marta & Sierra Nevada
  • Discover San Blas Islands' beaches
  • Visit and explore Fort San Lorenzo
  • Witness wildlife and ecosystems
Starts / Ends
Willemstad / Colon
Activities
Snorkeling, Archaeological Site Visits, Village Visits, Hiking
Activity Level
Variable
Explore the Caribbean on this 8-day Natural Sanctuaries & Heritage of the Caribbean cruise from Willemstad to Colon aboard the Le Champlain. Walk through UNESCO-listed cities, snorkel in the San Blas Islands, and meet the Kuna people. Visit Santa Marta’s mountains and the Fort San Lorenzo in Panama. Discover coral reefs, mangroves, and wildlife.
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
from $4,350
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends
Bridgetown / Balboa
Activity Level
Variable
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
Cruise Details
0
The vivid colors of the San Blas Islands
from $4,350
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Explore Balboa’s colonial charm
  • Transit Panama’s iconic canal
  • Discover San Blas culture
  • Enjoy Aruba’s clear waters
Starts / Ends
Balboa / St. John's
Activity Level
Variable
Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.
Cruise Details
0
The vivid colors of the San Blas Islands
from $4,240
EXPLORE

Barbados to Panama

Bridgetown - Balboa - 15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown’s heritage
  • Discover St. George’s coastal views
  • Admire Kralendijk’s marine life
  • Wander Willemstad’s streets
Starts / Ends
Bridgetown / Balboa
Activities
Wildlife Viewing, Small Ship Sailing, Local Market Visits
Activity Level
Variable
Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.
Cruise Details
0
Mountains by the ocean in St Lucia
from $8,490
EXPLORE

Panama, Colombia & Caribbean Islands

Colon to Fort-de-France - 13 Day Itinerary aboard Le Champlain
  • Sail through the Central America.
  • See San Blas, Bonaire & Grenadines
  • Experience swim and snorkel.
  • Learn traditions of the Kuna people
  • Dive with an experienced instructor
Starts / Ends
Colon / Fort de France
Activities
Land & Sea Exploration
Activity Level
Variable
Join Le Bellot for an exceptional 13-day cruise sailing from Colón to Fort-de-France. This itinerary gives you the opportunity to appreciate the richness and diversity of Afro-Caribbean cultures, an azure blue sky, and white-sand beaches. Visit stunning ports, including Portobelo, Cartagena, Santa Marta, Mayreau Island, and Soufriére.
Cruise Details
0
Starfish on the beach
from $131
EXPLORE

Bird Island and Starfish Beach

½ Day Itinerary
Activity Level
Relaxed
Tour Details
0
19-31 of 31 Results

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