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Ship in the Panama Canal

Top Panama Canal Tours & Cruises in 2025

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Discover Panama Canal in 2025 on one of these trips hand selected by the travel experts at Adventure Life. Select any of the below 13 top-rated trips where you will explore Panama Canal, Panama City, San Blas Islands, Colon, and Cartagena with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Panama Canal in are wildlife viewing, cruises, small ship cruises, snorkeling, and beaches. Our Panama Canal trips in 2025 range in price from $1,848 to $28,770 for trips of 7 to 15 days. Contact one of Adventure Life's expert Panama Canal trip planners for help planning a seamless experience.
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    • Panama Canal
Cathedral of Casco Viejo
$296
EXPLORE

Explore Panama City

  • Tour the ruins of Panama La Vieja
  • Watch a transit of the Panama Canal
Activities:
Land, Urban Exploration
Activity Level:
Relaxed
Tour Details
0
Keel-billed Toucan
$6,054
EXPLORE

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

8 Day Itinerary aboard Le Bellot
  • Cross the Panama Canal
  • Punta Culebra Nature Center at STRI
  • Snorkel on beautiful Holandes Cayes
  • See Darién National Park rainforest
Starts / Ends:
Colon / Puerto Caldera
Activities:
Rainforest Exploration, Small Ship Cruises, Snorkeling, Wildlife Viewing
Activity Level:
Variable
The San Blas Islands of Holandes Cayes, Panama City's Old Quarter, and the Darién National Park are highlights of Le Bellot's journey in Central America. Proceed to Fuente Amador and start your exploration of the Panama Canal. In Costa Rica, you may encounter sloths, the noisy howler …
Cruise Details
0
A jungle river in the rainforest
$1,847
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activities:
Rainforest Exploration, Village Visits, Wildlife Viewing, Ziplining
Activity Level:
Relaxed
Over 29% of Panama's landscape includes 15 national parks, forest reserves, and 10 wildlife sanctuaries - this itinerary is designed to visit some of the country's most celebrated. Begin your Panama travel journey with a cruise of the "8th wonder of the world", the Panama Canal, …
Tour Details
0
San Blas
$7,090
EXPLORE

Secrets of Central America

Colon - Puntarenas - 11 Day Itinerary aboard Le Bellot
  • Explore Fort San Lorenzo
  • Discover San Blas Islands
  • Experience Panama Canal
  • Swim in the Pearl Islands
Starts / Ends:
Colon / Puntarenas
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day expedition cruise from Colon to Puntarenas aboard the Le Bellot. Visit San Lorenzo’s Fort, an extraordinary fortress safeguarding transatlantic trade. Next, explore the San Blas Islands, home to the Kuna people and their vibrant craft of molas. Cross the legendary Panama …
Cruise Details
0
Tranquilo Bay indeed...
$3,522
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities:
Hiking, Land, Rainforest Exploration, Snorkeling, Whitewater Rafting, Wildlife Viewing, Zip Line
Activity Level:
Easy Active
This Adventure Life exclusive 9-day tour travels from Costa Rica to Panama on an activity-packed exploration of Central America's Caribbean coast. From Selva Bananito Lodge in Costa Rica, you will be able to explore the wild rainforest, zipline through the canopy, and ride the rapids of the …
Tour Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,830
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Trekking through Corcovado National Park in Costa Rica.
$6,601
EXPLORE

Costa Rica and the Panama Canal

San Jose - Panama - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Variable
Join the National Geographic Quest on this 8-day expedition to Costa Rica and the Panama Canal. Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in …
Cruise Details
0
Panama City's Bridge of the Americas
$11,675
EXPLORE

Once through the Panama Canal

Panama to Costa RIca - 11 Day Itinerary aboard Sea Cloud Spirit
  • Cruise through the Panama Canal
  • Encounter islands & national parks
  • Discover Palo Verde National Park
  • Spot Coatis, jaguars and birds
Starts / Ends:
Colon / Puntarenas
Activities:
Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day cruise through the historic Panama Canal, start in Panama City and experience a dinner cruise through the iconic Panama Canal, exploring Gatúnsee's unique islands like Barro Colorado in the rainforest. Sail through the canal's 12 lock basins, showcasing its …
Cruise Details
0
Gatun Lock of the Panama Canal
$3,830
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Zapatilla Cay, Panama
$6,741
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac …
Cruise Details
0
Crossing a stream on Osa Peninsula
$11,295
Savings
EXPLORE

Costa Rica & Panama Canal

Costa Rica - Colombia - 12 Day Itinerary aboard Greg Mortimer
  • Explore Costa Rica's wildlife
  • Discover vibrant bird species
  • Learn about the Emberá tribe
  • Cross the Panama Canal
  • Visit Curú National Wildlife Refuge
Starts / Ends:
San Jose / Colon
Activities:
Archaeological Site Visits, Photography Seminars, Scuba Diving, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Village Visits, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Immerse in the coastal landscapes of Costa Rica and Panama on this 12-day cruise aboard Greg Mortimer with travel photographer Richard I'Anson. Costa Rica stands as one of the world's most biodiverse regions, offering opportunities to explore lush tropical rainforests with a remarkable …
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,540
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Star Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Panama Canal
$3,580
EXPLORE

Discover the Panama Canal: Cruise from Panama to Belize

Panama to Belize - 11 Day Itinerary aboard SH Vega
  • Cruise Panama Canal
  • Visit Seaflower Biosphere Reserve
  • Explore Mesoamerican Barrier Reef
  • See 4,000 red footed boobies
Starts / Ends:
Panama City / Belize City
Activities:
Adventure Options, Land & Sea Exploration, Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day cruise aboard the SH Vega from Panama City to Belize. Start in Fuerte Amador, exploring Panama City’s historic sites before cruising the iconic Panama Canal. Navigate its 48-mile waterway, passing through locks and Gatun Lake. Experience Bocas del Toro’s pristine …
Cruise Details
0
1-13 of 13 Results
TrustScore 4.8 | 382 reviews
TrustScore 4.8 of 5
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Based on 382 reviews on
review score
1 day ago
The booking was processed efficiently and quickly. We got what we wanted.
Doug Laporte
review score
1 day ago
Great company. Good communications. Great accommodations, excursions, transport. Guide Elvira was spectacular along with transport, driver, Cesar and activities
Kathy S
review score
2 days ago
Very responsive to questions. Helpful with all arrangements
Roz
review score
3 days ago
The ship company they sent us on was perfect in every detail
lisa wegener
review score
4 days ago
I’m so glad we found AdventureLife. Jess, our planner, was such a pleasure to work with. She readily shared her extensive knowledge about Panama, she offered good suggestions and creative ideas, kept everything organized and handled the details each step of the way.
Tim King

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