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Ship in the Panama Canal

Top Panama Canal Tours & Cruises in 2025

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Discover the best the world has to offer with Adventure Life’s expert-curated Panama Canal tours 2025. From to hidden gems off the beaten path, our 14 top-rated itineraries take you deep into Panama Canal’s breathtaking landscapes. Guided by bilingual experts, these immersive experiences cater to adventurers seeking unique journeys in small groups or customizable private tours.

Choose from a variety of 5 to 15 days itineraries starting at $277 to $23,995. You’ll find options that suit your travel style. Whether you’re passionate about Wildlife Viewing, Hiking, Snorkeling, Rainforest Exploration, and Small Ship Sailing or eager to explore Panama Canal’s rich culture and natural beauty, our Panama Canal tours 2025 deliver unforgettable moments. Each itinerary blends awe-inspiring exploration with a commitment to sustainability to ensure your adventure supports the preservation of our planet.

Adventure Life’s dedication to personalized travel promises your Panama Canal tour 2025 is seamless from start to finish. From arranging transportation to selecting accommodations tailored to your preferences, we’ll take care of every detail. Our expert recommendations and insider tips make your journey even more enriching.

Contact our specialists today to start planning your Panama Canal tour 2025. Whether you’re a solo traveler, a couple, or part of a group, Adventure Life will create a transformative experience you’ll treasure forever.
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    • Panama Canal
Wild Collared Aracari Toucan in Panama's Gamboa Jungle
from $2,010
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activity Level
Relaxed
Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!
Tour Details
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Tranquilo Bay indeed...
from $3,787
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities
Whitewater Rafting
Activity Level
Easy Active
Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!
Tour Details
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Guests explore by zodiac cruise in Portobelo, Panama
from $6,150
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Explore Darien Jungle
  • Visit Portobelo Forts
  • Snorkel Pearl Islands
Starts / Ends
Panama City / Balboa
Activities
Village Visits, Wildlife Viewing, Hiking, Snorkeling, Urban Exploration, Kayaking, Stand Up Paddle Boarding
Activity Level
Variable
Embark on an 8-day Panama Canal cruise to the Pearl Islands and Darien Jungle aboard the National Geographic Quest. Transit the legendary Panama Canal, meet the Emberá people in Playa Muerto, spot wildlife in Punta Patiño, and snorkel the clear waters of the Pearl Islands, including Isla del Rey and Isla Pacheca.
Cruise Details
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Panama Canal
from $8,174
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EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities
Land & Sea Exploration, Horseback Riding
Activity Level
Variable
Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
0
from $3,590
EXPLORE

Discover Panama

8 Day Itinerary
  • Trek the lowland tropical forest
  • Bike, hike, zipline, raft or relax
  • See wildlife in natural habitats
  • Explore Tranquilo Bay
Activities
Ziplining, Biking
Activity Level
Easy Active
This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.
Tour Details
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Boats Moored to the Quay at Bridgetown Harbour
from $4,450
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends
Bridgetown / Balboa
Activity Level
Variable
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
Cruise Details
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Sunset over Cartagena, Colombia
from $6,450
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EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

Panama to Cartagena - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends
Panama City / Cartagena
Activity Level
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.
Cruise Details
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Panama's turquoise waters
from $4,450
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Explore Balboa’s colonial charm
  • Transit Panama’s iconic canal
  • Discover San Blas culture
  • Enjoy Aruba’s clear waters
Starts / Ends
Balboa / St. John's
Activity Level
Variable
Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.
Cruise Details
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The vivid colors of the San Blas Islands
from $4,330
EXPLORE

Barbados to Panama

Bridgetown - Balboa - 15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown’s heritage
  • Discover St. George’s coastal views
  • Admire Kralendijk’s marine life
  • Wander Willemstad’s streets
Starts / Ends
Bridgetown / Balboa
Activities
Small Ship Sailing, Archaeological Site Visits, Local Market Visits
Activity Level
Variable
Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.
Cruise Details
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Look for unique birds and other wildlife in the rain forest!
from $12,955
Save 50%
EXPLORE

Natural Wonders, Engineering Marvels

Puntarenas - Colon - 13 Day Itinerary aboard Sea Cloud Spirit
  • Explore Nicoya Peninsula beaches
  • Visit Pearl Islands Discover Pea
  • Discover Marina Flamingo
  • Relax at Playa Panama
  • Sail through the Panama Canal
Starts / Ends
Puntarenas / Colon
Activities
Rainforest Exploration, Fishing
Activity Level
Variable
Experience the essence of “Pura Vida” on a 13-day Panama cruise from Puntarenas to Colon. Visit Punta Leona, Marina Flamingo, Playa Panama, Quepos, Puerto Jimenez, the Pearl Islands, and the San Blas Archipelago, exploring rainforests, beaches, & marinas while encountering diverse wildlife and witnessing the engineering marvel of the Panama Canal.
Cruise Details
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Transitioning the Panama Canal
from $323
EXPLORE

Panama Canal Full Transit

1 Day Itinerary
  • See the Panama City skyline
  • Learn the history of the canal
Activity Level
Relaxed
This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.
Tour Details
0
View of the Miraflores Locks
from $276
EXPLORE

Panama Canal Partial Transit

½ Day Itinerary
  • Transit through Miraflores Locks
  • Learn the history of the canal
Activity Level
Relaxed
Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.
Tour Details
0
Cathedral of Casco Viejo
from $311
EXPLORE

Explore Panama City

½ Day Itinerary
  • Tour the ruins of Panama La Vieja
  • Watch a transit of the Panama Canal
Activity Level
Relaxed
Tour Panama City with a local guide, well versed in the history of the area. See a transit of the Panama canal and tour Casco Antiguo where the pirate Henry Morgan waged his attack in 1671.
Tour Details
0
An old fort of Panama
from $355
EXPLORE

San Lorenzo and Agua Claras Locks

1 Day Itinerary
  • Visit historic San Lorenzo Fort
  • Visit the Gatun Locks
  • Witness Panama Canal expansion
Activity Level
Relaxed
Visit Aguas Clara Visitor Center for stunning Gatun Lake views and marvel at the historic San Lorenzo Fort. Explore scenic landscapes, rich wildlife, and Panama Canal expansion highlights in one action-packed day.
Tour Details
0
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