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Ship in the Panama Canal

Panama Canal Cruises

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Experience the wonders of the Panama Canal with our 12 enriching cruises for 2025. Join us on a cruise journey through this engineering marvel, exploring the lush rainforests, vibrant wildlife, and rich cultural heritage of Panama. From the bustling city of Panama City to the serene islands of the Caribbean coast, each moment offers a unique opportunity to immerse yourself in the beauty and history of this region. Engage in wildlife viewing, village visits, and hiking adventures while surrounded by the natural splendor that has inspired explorers for centuries. With cruises ranging from 8 to 15 days, there's something for every traveler seeking a blend of adventure and relaxation. Don't miss this chance to navigate the Panama Canal and discover the hidden gems of Central America. Contact one of Adventure Life's Panama specialists for help planning your next seamless trip.
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Explore beautiful Costa Rica
$6,420
EXPLORE

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

Colón - Puntarenas - 8 Day Itinerary aboard Le Champlain
  • Discover San Blas
  • Experience Panama Canal
  • Explore Fuerte Amador
  • Visit Darien National Park
Starts / Ends:
Colon / Puntarenas
Activities:
Small Ship Cruises, Snorkeling, Village Visits, Wildlife Viewing
Activity Level:
Variable
Embark on an 8-day cruise aboard Le Champlain to explore the natural splendors and cultural richness of Panama and Costa Rica. Start your journey in Holandes Cayes, part of Panama's San Blas Islands, known for their white sands and clear waters, perfect for swimming and snorkeling. Sail through …
Cruise Details
0
Keel-billed Toucan
$6,054
EXPLORE

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

8 Day Itinerary aboard Le Bellot
  • Cross the Panama Canal
  • Punta Culebra Nature Center at STRI
  • Snorkel on beautiful Holandes Cayes
  • See Darién National Park rainforest
Starts / Ends:
Colon / Puerto Caldera
Activities:
Rainforest Exploration, Small Ship Cruises, Snorkeling, Wildlife Viewing
Activity Level:
Variable
The San Blas Islands of Holandes Cayes, Panama City's Old Quarter, and the Darién National Park are highlights of Le Bellot's journey in Central America. Proceed to Fuente Amador and start your exploration of the Panama Canal. In Costa Rica, you may encounter sloths, the noisy howler …
Cruise Details
0
San Blas
$7,090
EXPLORE

Secrets of Central America

Colon - Puntarenas - 11 Day Itinerary aboard Le Bellot
  • Explore Fort San Lorenzo
  • Discover San Blas Islands
  • Experience Panama Canal
  • Swim in the Pearl Islands
Starts / Ends:
Colon / Puntarenas
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day expedition cruise from Colon to Puntarenas aboard the Le Bellot. Visit San Lorenzo’s Fort, an extraordinary fortress safeguarding transatlantic trade. Next, explore the San Blas Islands, home to the Kuna people and their vibrant craft of molas. Cross the legendary Panama …
Cruise Details
0
$7,820
EXPLORE

Secrets of Central America

Colón - Puntarenas - 11 Day Itinerary aboard Le Champlain
  • Discover National Parks
  • Sail through the Panama Canal
  • Encounter with Emberas tribe
  • Visit San Blas archipelago
Starts / Ends:
Puerto Caldera / Colon
Activities:
Archaeological Site Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Join this 11-day Secrets of Central America cruise expedition from Colon to Puntarenas aboard Le Champlain and explore the natural beauty of Panama and Costa Rica. Starting at San Lorenzo’s Fort, a UNESCO World Heritage site, travel from the Atlantic to the Pacific, visiting places like the …
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,830
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Trekking through Corcovado National Park in Costa Rica.
$6,601
EXPLORE

Costa Rica and the Panama Canal

San Jose - Panama - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Variable
Join the National Geographic Quest on this 8-day expedition to Costa Rica and the Panama Canal. Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in …
Cruise Details
0
Panama City's Bridge of the Americas
$11,675
EXPLORE

Once through the Panama Canal

Panama to Costa RIca - 11 Day Itinerary aboard Sea Cloud Spirit
  • Cruise through the Panama Canal
  • Encounter islands & national parks
  • Discover Palo Verde National Park
  • Spot Coatis, jaguars and birds
Starts / Ends:
Colon / Puntarenas
Activities:
Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day cruise through the historic Panama Canal, start in Panama City and experience a dinner cruise through the iconic Panama Canal, exploring Gatúnsee's unique islands like Barro Colorado in the rainforest. Sail through the canal's 12 lock basins, showcasing its …
Cruise Details
0
Crossing a stream on Osa Peninsula
$11,295
Savings
EXPLORE

Costa Rica & Panama Canal

Costa Rica - Colombia - 12 Day Itinerary aboard Greg Mortimer
  • Explore Costa Rica's wildlife
  • Discover vibrant bird species
  • Learn about the Emberá tribe
  • Cross the Panama Canal
  • Visit Curú National Wildlife Refuge
Starts / Ends:
San Jose / Colon
Activities:
Archaeological Site Visits, Photography Seminars, Scuba Diving, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Village Visits, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Immerse in the coastal landscapes of Costa Rica and Panama on this 12-day cruise aboard Greg Mortimer with travel photographer Richard I'Anson. Costa Rica stands as one of the world's most biodiverse regions, offering opportunities to explore lush tropical rainforests with a remarkable …
Cruise Details
0
Gatun Lock of the Panama Canal
$3,830
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Zapatilla Cay, Panama
$6,741
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac …
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,540
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Star Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Panama Canal
$3,580
EXPLORE

Discover the Panama Canal: Cruise from Panama to Belize

Panama to Belize - 11 Day Itinerary aboard SH Vega
  • Cruise Panama Canal
  • Visit Seaflower Biosphere Reserve
  • Explore Mesoamerican Barrier Reef
  • See 4,000 red footed boobies
Starts / Ends:
Panama City / Belize City
Activities:
Adventure Options, Land & Sea Exploration, Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day cruise aboard the SH Vega from Panama City to Belize. Start in Fuerte Amador, exploring Panama City’s historic sites before cruising the iconic Panama Canal. Navigate its 48-mile waterway, passing through locks and Gatun Lake. Experience Bocas del Toro’s pristine …
Cruise Details
0
1-12 of 12 Results
TrustScore 4.8 | 380 reviews
TrustScore 4.8 of 5
total score
Based on 380 reviews on
review score
6 hours ago
Very responsive to questions. Helpful with all arrangements
Roz
review score
1 day ago
The ship company they sent us on was perfect in every detail
lisa wegener
review score
2 days ago
I’m so glad we found AdventureLife. Jess, our planner, was such a pleasure to work with. She readily shared her extensive knowledge about Panama, she offered good suggestions and creative ideas, kept everything organized and handled the details each step of the way.
Tim King
review score
3 days ago
Jessica was wonderful! She made every effort to ensure our trip was just what we wanted.
Celine Krafft
review score
3 days ago
Erin was easy to work with and very helpful. She was patient and helped us figure out the adventure tour we were hoping for in Belize. Can’t wait to go on this trip!
Sam Wedll

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