Upper Mississippi River
St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Melody
- Explore the culture of St. Louis
- See Mark Twain's hometown, Hannibal
- Witness wildlife and nature
- Admire local artwork in Red Wing
- Starts / Ends
- St. Louis / Red Wing
- Activity Level
- Variable
Explore the segment of the Mississippi River on this 9-day cruise from St. Louis to Minneapolis American Melody. Begin in St. Louis, Missouri, and through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.