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United States River Cruises

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Sunrise over Crown Point at Columbia River
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Discover the glorious beauty of the United States on a river cruise with Adventure Life in 2025. With 28 diverse tours available, ranging from 6 to 16 days in length, you can sail through iconic American landscapes, cities, and cultural sites. Navigating the country's waterways offers a unique perspective, allowing you to discover the beauty of the Mississippi River, the Columbia and Snake Rivers, or even the Intracoastal Waterway. Wildlife enthusiasts will delight in the opportunity for wildlife viewing, while history buffs can explore archaeological sites along the riverbanks. Adventure Life river cruise experts can match you up on the best US river cruise for every traveler's taste. Visit the United States and contact us for help planning your next seamless adventure.
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View the iconic arch when you visit St. Louis, gateway to the west
from $12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends
St. Paul / New Orleans
Activity Level
Variable
Cruise America's great river on this 15-day itinerary aboard Viking Mississippi. Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Along the way, visit historic ports such as St. Louis, Memphis, Baton Rouge, and more.
Cruise Details
0
Wander through the historic French Quarter
from $3,499
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends
New Orleans / New Orleans
Activities
Festival Visits
Activity Level
Variable
Explore the highlights of the Mississippi River on this 8-day cruise roundtrip from New Orleans aboard Viking Mississippi. Discover port cities such as St. Francisville, Darrow, Baton Rouge, Natchez, and Vicksburg to experience the diverse culture and rich history of the lower Mississippi region.
Cruise Details
0
Sunrise at Crown Point, Columbia River Gorge, Oregon
from $4,165
Save 20%
EXPLORE

Columbia and Snake Rivers: Food, Wine, and History - Eastbound

Portland - Clarkston - 6 Day Itinerary aboard National Geographic Sea Lion
  • Sail under Portland’s iconic bridge
  • See majestic Multnomah Falls
  • Taste wine in charming Walla Walla
  • Visit historic Whitman Mission site
Starts / Ends
Portland / Clarkston
Activities
Wildlife Viewing, Kayaking, Wine Tasting, Hiking
Activity Level
Variable
Experience a 6-day cruise on the Columbia and Snake rivers aboard the National Geographic Sea Lion, and savor exquisite local cuisine and wines curated by Food & Wine's Ray Isle. Explore stunning landscapes through guided hikes and kayaking while learning about the region's rich history and geology from expert naturalists.
Cruise Details
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Visit Louisiana's capital city of Baton Rouge
from $3,630
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Experience Natchez’s beauty
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends
New Orleans / New Orleans
Activity Level
Variable
The American Heritage hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.
Cruise Details
0
Visit historic Memphis, Tennessee
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Columbia River Gorge
from $2,640
Savings
EXPLORE

Highlights of the Columbia River

Portland Roundtrip - 6 Day Itinerary aboard American Pride
  • Discover Astoria's charm
  • Learn about Mount St. Helens' erupt
  • Admire the Columbia River Gorge
Starts / Ends
Portland / Portland
Activity Level
Variable
Set sail aboard the American Pride for a 6-day Columbia River cruise. Admire Mount Hood and Mount St. Helens. Explore Astoria's Victorian charm. Discover Cape Disappointment and Fort Clatsop. Experience Mount St. Helens' eruption history. Immerse in Kalama's past. Marvel at Multnomah Falls and Bonneville Dam. Every day, a new wonder awaits.
Cruise Details
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Scenic Landscape
from $5,827
EXPLORE

Columbia and Snake Rivers: Food, Wine, and History - Eastbound

Portland - Clarkston - 8 Day Itinerary aboard National Geographic Sea Lion
  • Bike or walk along the river
  • Zodiak or kayak the Palouse River
  • Jet boat through Hells Canyon
  • Explore the Lewis & Clark Refuge
Activity Level
Variable
The Sea Lion hosts this 8-day excursion from Portland, Oregon towards Clarkston, Washington. Along the way, pass through Hells Canyon, visit the Lewis and Clark Wildlife Refuge, zodiac & kayak your way along the Palouse River, and witness the Columbia River Gorge.
Cruise Details
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Vanderbilt Mansion National Historic Site
from $7,235
Savings
EXPLORE

Hudson River Fall Foliage

New York Roundtrip - 8 Day Itinerary aboard American Glory
  • Visit the Kaaterskill Falls
  • Explore the New York State Museum
  • Enjoy cheese and apple tasting
  • Learn the marine history
Starts / Ends
New York / New York
Activity Level
Variable
Join the 8-day Hudson River Fall Foliage cruise aboard American Glory from New York. Witness vibrant autumn colors along the river and explore historic ports of call like the Vanderbilt Mansion and West Point, guided by local experts. Relax on the American Liberty, enjoying cocktails and regionally-inspired cuisine with fellow travelers.
Cruise Details
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View monuments from the Civil War in Mississippi
from $4,530
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Columbia River Gorge
from $3,315
Savings
EXPLORE

Columbia River Gorge Cruise

Roundtrip Portland - 7 Day Itinerary aboard American Pride
  • Discover Hood River’s museums
  • Walk through The Dalles
  • Visit Mount St. Helens
  • Taste local wines from Hood River
Starts / Ends
Portland / Portland
Activities
Small Ship Sailing
Activity Level
Variable
Set sail on a 7-day Columbia River Gorge cruise aboard American Pride. Explore Portland, Hood River, The Dalles, and Kalama. Discover the pioneers at the Oregon Trail’s end and learn about the region’s history at museums like the Columbia Gorge Discovery Center and the Fort Dalles Museum. Highlights include Mount St. Helens, wine tastings, and onboard relaxation.
Cruise Details
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The still water of the Palouse River
from $5,827
EXPLORE

Columbia and Snake Rivers: Food, Wine, and History

Fall Season - 8 Day Itinerary aboard National Geographic Sea Bird
  • Trek up the iconic Beacon Rock
  • Zodiak or kayak the Palouse River
  • Jet boat through Hells Canyon
  • Explore the Lewis & Clark Refuge
Activity Level
Variable
The Sea Bird takes you on this 8-day Pacific Northwest cruise along the Columbia and Snake Rivers, including zodiac & kayak excursions, hiking and biking opportunities, and visits to the Lewis and Clark Wildlife Refuge, the Columbia River Gorge, and Hells Canyon.
Cruise Details
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Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $12,620
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends
St. Paul / New Orleans
Activities
Biking, Local Market Visits
Activity Level
Variable
Embark on a 16-day Mississippi River cruise from Minnesota to Louisiana aboard American Serenade, exploring St. Paul to New Orleans with stops in La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, and Natchez. Enjoy onboard activities, stunning scenery, and experiences like the Mark Twain Boyhood Home and more.
Cruise Details
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Vicksburg Battlefield overlooking the Mississippi River
from $3,999
EXPLORE

Mississippi Delta Explorer

New Orleans - Memphis - 8 Day Itinerary aboard Viking Mississippi
  • Explore Darrow
  • Visit Natchez historic sites
  • Learn the history of Vicksburg
  • Culinary adventure of Mississippi
  • Know the history of rock 'n' roll
  • American South's Cultural Heritage
Starts / Ends
New Orleans / Memphis
Activities
Urban Exploration, Archaeological Site Visits, Village Visits
Activity Level
Variable
On this 8-day Mississippi Delta Explorer from New Orleans to Memphis aboard the Viking Mississippi, visit historic towns like Darrow, Natchez, and Vicksburg. Enjoy Cajun and Creole cuisine, Memphis barbecue, and explore the South’s rich history, culture, and music.
Cruise Details
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Columbia River Gorge
from $5,715
Savings
EXPLORE

Columbia & Snake Rivers Cruise

Portland - Clarkston - 9 Day Itinerary aboard American Song
  • Explore Astoria's Victorian charm
  • Step ashore in Kalama
  • Discover Richland's scenic trails
  • Cruise the legendary Snake River
Starts / Ends
Portland / Richland
Activity Level
Variable
Embark on a 9-day cruise aboard American Song, navigating the Columbia & Snake Rivers. Cruise past Mount Hood and Mount St. Helens, reliving the golden age of riverboats. Explore Astoria's Victorian charm and visit Fort Clatsop. Journey through history in The Dalles, Richland, and Pendleton, culminating in the majestic landscapes of Hells Canyon.
Cruise Details
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Mississippi River, St. Paul Minnesota
from $5,545
Savings
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Melody
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends
St. Louis / Red Wing
Activity Level
Variable
Explore the segment of the Mississippi River on this 9-day cruise from St. Louis to Minneapolis American Melody. Begin in St. Louis, Missouri, and through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.
Cruise Details
0
Explore beautiful Nashville
from $4,915
Savings
EXPLORE

Music Cities Cruise

Memphis, TN to Nashville, TN - 9 Day Itinerary aboard American Symphony
  • Explore Memphis
  • Discover Paducah
  • Experience Lake Barkley
  • Enjoy Nashville
Starts / Ends
Memphis / Nashville
Activity Level
Variable
Set sail on a 9-day cruise on the American Symphony from Memphis to Nashville, traversing the Mississippi, Ohio, and Cumberland rivers—Immerse in local music, nightly entertainment, and Southern cuisine amid America's heartland's scenic beauty.
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from $4,295
Savings
EXPLORE

Lower Mississippi River Cruise

9 Day Itinerary aboard American Splendor
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Admire the diversity of New Orleans
  • Visit Myrtles' haunted estate
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activities
Cooking Classes
Activity Level
Variable
Experience a 9-day cruise aboard American Melody from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
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