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Bridge across the Mississippi at Cape Girardeau

Cape Girardeau River Cruises

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Experience the quaint charm and beauty of Cape Girardeau with Adventure Life's 1 diverse Cruises for 2025. Join us on a cruise journey through this picturesque city along the Mississippi River, where you can explore historic sites, enjoy local cuisine, and immerse yourself in the vibrant culture of the region. From wine tasting to wildlife viewing, each tour offers a unique opportunity to discover the best of Cape Girardeau. Whether you're interested in cultural experiences, food & wine adventures, or simply relaxing on a luxury cruise, there's something for everyone in this hidden gem of Missouri. Don't miss this chance to sail through the heart of Cape Girardeau and create unforgettable memories. Contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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Visit historic Minneapolis
from $15,890
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Complete Mississippi River

New Orleans - St. Paul - 23 Day Itinerary aboard American Melody
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
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New Orleans / St. Paul
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Urban Exploration, Village Visits, Wine Tasting, Local Market Visits, Archaeological Site Visits
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Variable
Discover the Mighty Mississippi on a 23-day cruise covering 10 states aboard American Melody. Immerse in history, culture, and cuisine from New Orleans to Minneapolis, exploring charming ports along the way.
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