Upper Mississippi River
St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Symphony
- Explore Mark Twain’s hometown
- Cruise through historic towns
- Explore St. Paul's grand mansions
- Visit National River Museum
- Starts / Ends
- St. Louis / Red Wing
- Activities
- Wine Tasting
- Activity Level
- Variable
Explore the segment of the Mississippi River on this 9-day cruise from St. Louis to Minneapolis American Symphony. Begin in St. Louis, Missouri, and through Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's boyhood home, explore historic towns, and marvel at the diverse landscapes.