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Louisiana Mississippi River Cruises

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Experience the vibrant culture and rich history of Louisiana with Adventure Life's collection of 11 captivating River Cruises for 2025. Navigate through the heart of Cajun Country, where you can immerse yourself in the mesmerizing sounds of jazz, savor the exquisite flavors of Creole cuisine, and witness the colorful architecture of New Orleans. Discover the mystical swamps and bayous, home to abundant wildlife like alligators and exotic birds. Sail along the mighty Mississippi River, exploring charming antebellum plantations and historic towns that showcase the state's diverse heritage. From lively music scenes to mouthwatering culinary experiences, these River Cruises offer a perfect blend of cultural immersion and natural beauty that Louisiana is renowned for. Don't miss the chance to embark on a journey filled with unique experiences and unforgettable memories. Contact one of our award-winning river cruise experts for help planning your next seamless trip.
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    • Louisiana
View the iconic arch when you visit St. Louis, gateway to the west
from $12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends
St. Paul / New Orleans
Activity Level
Variable
Cruise America's great river on this 15-day itinerary aboard Viking Mississippi. Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Along the way, visit historic ports such as St. Louis, Memphis, Baton Rouge, and more.
Cruise Details
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Wander through the historic French Quarter
from $3,499
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends
New Orleans / New Orleans
Activities
Festival Visits, Cooking Classes
Activity Level
Variable
Explore the highlights of the Mississippi River on this 8-day cruise roundtrip from New Orleans aboard Viking Mississippi. Discover port cities such as St. Francisville, Darrow, Baton Rouge, Natchez, and Vicksburg to experience the diverse culture and rich history of the lower Mississippi region.
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from $3,630
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Experience Natchez’s beauty
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends
New Orleans / New Orleans
Activity Level
Variable
The American Heritage hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.
Cruise Details
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Explore historic New Orleans
from $4,190
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Melody
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends
New Orleans / New Orleans
Activity Level
Variable
The American Melody hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.
Cruise Details
0
Vicksburg Battlefield overlooking the Mississippi River
from $3,999
EXPLORE

Mississippi Delta Explorer

New Orleans - Memphis - 8 Day Itinerary aboard Viking Mississippi
  • Explore Darrow
  • Visit Natchez historic sites
  • Learn the history of Vicksburg
  • Culinary adventure of Mississippi
  • Know the history of rock 'n' roll
  • American South's Cultural Heritage
Starts / Ends
New Orleans / Memphis
Activities
Urban Exploration, Archaeological Site Visits, Village Visits
Activity Level
Variable
On this 8-day Mississippi Delta Explorer from New Orleans to Memphis aboard the Viking Mississippi, visit historic towns like Darrow, Natchez, and Vicksburg. Enjoy Cajun and Creole cuisine, Memphis barbecue, and explore the South’s rich history, culture, and music.
Cruise Details
0
Visit historic Memphis, Tennessee
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from $4,295
Savings
EXPLORE

Lower Mississippi River Cruise

9 Day Itinerary aboard American Splendor
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
from $5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Melody from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
View monuments from the Civil War in Mississippi
from $4,530
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Vicksburg Battlefield overlooking the Mississippi River
from $4,530
Savings
EXPLORE

Lower Mississippi River Cruise

New Orleans - Memphis - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
New Orleans / Memphis
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from New Orleans to Memphis, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $12,620
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends
St. Paul / New Orleans
Activity Level
Variable
Embark on a 16-day Mississippi River cruise from Minnesota to Louisiana aboard American Serenade, exploring St. Paul to New Orleans with stops in La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, and Natchez. Enjoy onboard activities, stunning scenery, and experiences like the Mark Twain Boyhood Home and more.
Cruise Details
0
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