Grand Heartland Cruise
Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
- Visit mansions and art galleries
- See the Gateway Arch and St. Louis
- Visit Natchez’s antebellum homes
- Experience Memphis' musical legacy
- Starts / Ends
- St. Paul / New Orleans
- Activity Level
- Variable
Embark on a 16-day Mississippi River cruise from Minnesota to Louisiana aboard American Serenade, exploring St. Paul to New Orleans with stops in La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, and Natchez. Enjoy onboard activities, stunning scenery, and experiences like the Mark Twain Boyhood Home and more.