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Top Panama Canal Trips & Tours in November 2025

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Discover Panama Canal in November 2025 on one of these 8 tours hand-selected by the travel experts at Adventure Life. Explore the best of Panama Canal, Panama City, Cartagena, San Blas Islands, and St. Georges during November 2025 as you enjoy wildlife viewing, snorkeling, small ship cruises, cruises, and small ship sailing. Prices for trips in November 2025 range from $1,848 to $11,662 for a vacation of 7 to 15 days. Choose any of the below 8 itineraries in November 2025 and customize it when you contact one of Adventure Life's expert Panama Canal trip planners.
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Cathedral of Casco Viejo
$296
EXPLORE

Explore Panama City

  • Tour the ruins of Panama La Vieja
  • Watch a transit of the Panama Canal
Activities:
Land, Urban Exploration
Activity Level:
Relaxed
Tour Details
0
A jungle river in the rainforest
$1,847
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activities:
Rainforest Exploration, Village Visits, Wildlife Viewing, Ziplining
Activity Level:
Relaxed
Over 29% of Panama's landscape includes 15 national parks, forest reserves, and 10 wildlife sanctuaries - this itinerary is designed to visit some of the country's most celebrated. Begin your Panama travel journey with a cruise of the "8th wonder of the world", the Panama Canal, …
Tour Details
0
Tranquilo Bay indeed...
$3,522
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities:
Hiking, Land, Rainforest Exploration, Snorkeling, Whitewater Rafting, Wildlife Viewing, Zip Line
Activity Level:
Easy Active
This Adventure Life exclusive 9-day tour travels from Costa Rica to Panama on an activity-packed exploration of Central America's Caribbean coast. From Selva Bananito Lodge in Costa Rica, you will be able to explore the wild rainforest, zipline through the canopy, and ride the rapids of the …
Tour Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,830
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Trekking through Corcovado National Park in Costa Rica.
$6,601
Savings
EXPLORE

Costa Rica & the Panama Canal

8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Variable
Join the National Geographic Quest on this 8-day expedition to Costa Rica and the Panama Canal. Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in …
Cruise Details
0
Gatun Lock of the Panama Canal
$3,640
EXPLORE

Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Zapatilla Cay, Panama
$6,290
Savings
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac …
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
$3,540
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Star Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
1-8 of 8 Results
TrustScore 4.9 | 306 reviews
TrustScore 4.9 of 5
total score
Based on 306 reviews on
review score
1 day ago
Tony and Shannon were always quick to answer my questions and requests. They booked my Upper Mississippi cruise perfectly. They made sure that my dietary needs were met which is a big deal for me. I have the utmost confidence with their assistance.
Code
review score
2 days ago
Third trip we have book with Adventure Life. Like the last two, we have had a quick response to all inquires
Carol Borland
review score
2 days ago
Angela was fantastic! She was thoughtful, helpful, and prompt in her responses without being intrusive. She accommodated our large group and was genuinely excited for us when it all worked out. Can't say enough good things! This is our second trip booking through Adventure Life and we will definitely do it again.
Emily
review score
3 days ago
Jessica was extremely helpful and generous with her time. She was very responsive to our questions and comments and in a very timely fashion. She worked with us in partnership to plan a trip specifically for us and our wants and needs.
Linda Coleman
review score
3 days ago
Mary Curry found right trip for my budget and the best date that I liked. She made that reservation when other company's agent could not do it. Thank you so much!
Theresa AN

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