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Sunset over Cartagena, Colombia

Cartagena Cruises & Tours

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Cartagena, Colombia's most important port on the Caribbean coast, is home to a World Heritage old town surrounded by walls, colonial plazas, fortresses, and white-sand beaches. Choose one of these top Cartagena tours for 2025 and 2026 and explore this magical city accompanied by your own local English-speaking guide. These Cartagena trips feature activities such as wildlife viewing, snorkeling, hiking, and visits to villages and local markets. Most of the trips can be customized to meet your exact needs, while cruises have fixed itineraries. Contact one of Adventure Life's Cartagena tour specialists to start planning your next adventure.

10 Best Cartagena Cruises & Tours for 2025-2026

Zapatilla Cay, Panama

Panama and Colombia: Exploring the Caribbean Coast

Panama City to Cartagena
8 Days from $6,741
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, San Bernardo Archipelago, and more.
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Traditional Maracas in Colombia

Magic of Colombia

Barranquilla - Cartagena
8 Days from $3,839
Embark on an 8-day cruise from Barranquilla to Cartagena aboard the AmaMelodia and experience the allure of Colombia. Discover the rich culture and traditions of San Agustin, Mompox, and La Dorada, and indulge in Colombia's famous coffee. Encounter the country's unique flora and fauna as you journey through this diverse and captivating land.
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Boats Moored to the Quay at Bridgetown Harbour

Barbados to Panama

Bridgetown to Balboa
15 Days from $3,830
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
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Gatun Lock of the Panama Canal

Panama to Antigua

15 Days from $3,830
Starting in Balboa, Panama, sail through warm Caribbean waters as you make your way to the Antigua aboard the Royal Clipper. Over the course of 15 days visit Grenada, Bonaire, Curacao, Aruba, and Colombia before arriving in Panama.
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Boats Moored to the Quay at Bridgetown Harbour

Barbados to Panama

Bridgetown to Balboa
15 Days from $3,720
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Star Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Tobago Cays, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, Experience tribal culture, and the Panama Canal.
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Whitewater Rafting during Colombia Tour

Andes to Caribbean Multisport

12 Days from $5,210
On this 12-day active multisport tour of Colombia, you'll hike, bike, and whitewater raft through the Andes before descending to the Caribbean coast to the Tayrona National Park and charming and historic Cartagena. Along the way, you'll see Chicamocha Gorge, tour an authentic coffee hacienda, and hike to the lost stone city of El Pueblito.
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Magdalena River, Colombia

Wonders of Colombia

Barranquilla to Cartagena
8 Days from $3,839
Immerse in Colombia's wonders on this 8-day cruise along the Magdalena River aboard AmaMagdalena. Explore Palenque, the first free city, and vibrant Getsemaní in Cartagena. Discover the fusion of cultures, music, and art that shape the country.
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Mompox, Colombia

Wonders of Colombia

Cartagena - Barranquilla
8 Days from $3,839
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
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Gaze at the balconies overlooking the breathtaking cathedral in Cartagena, Colombia

Just Drifting Along

Willemstad - Panama
9 Days from $8,565
Set sail on a 9-day cruise aboard the Sea Cloud Spirit, exploring the ABC islands, including Curacao's UNESCO-listed Willemstad and Aruba's colorful Oranjestad. Visit Cartagena's historic colonial streets, relax at sea, and end your journey in Panama's San Blas Archipelago and Colon.
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San Pedro Claver Plaza, Cartagena

Colombia Highlights

Bogota to Cartagena
9 Days from $2,421
Enjoy a complete 9-day tour discovering the highlights of Colombia. Dance the salsa and explore the city of Bogota, visit the Wax Palm reserve in Salamina, and taste the best coffee in Manizales. Finally, discover the rich culture preserved in Cartagena. Visit multiple parts of Colombia and see the best that each place has to offer.
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10 Best Luxury Cartagena Cruises & Tours for 2025-2026

Zapatilla Cay, Panama

Panama and Colombia: Exploring the Caribbean Coast

Panama City to Cartagena
8 Days from $6,741
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, San Bernardo Archipelago, and more.
0
Traditional Maracas in Colombia

Magic of Colombia

Barranquilla - Cartagena
8 Days from $3,839
Embark on an 8-day cruise from Barranquilla to Cartagena aboard the AmaMelodia and experience the allure of Colombia. Discover the rich culture and traditions of San Agustin, Mompox, and La Dorada, and indulge in Colombia's famous coffee. Encounter the country's unique flora and fauna as you journey through this diverse and captivating land.
0
Boats Moored to the Quay at Bridgetown Harbour

Barbados to Panama

Bridgetown to Balboa
15 Days from $3,830
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
0
Gatun Lock of the Panama Canal

Panama to Antigua

15 Days from $3,830
Starting in Balboa, Panama, sail through warm Caribbean waters as you make your way to the Antigua aboard the Royal Clipper. Over the course of 15 days visit Grenada, Bonaire, Curacao, Aruba, and Colombia before arriving in Panama.
0
Boats Moored to the Quay at Bridgetown Harbour

Barbados to Panama

Bridgetown to Balboa
15 Days from $3,720
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Star Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Tobago Cays, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, Experience tribal culture, and the Panama Canal.
0
Whitewater Rafting during Colombia Tour

Andes to Caribbean Multisport

12 Days from $5,210
On this 12-day active multisport tour of Colombia, you'll hike, bike, and whitewater raft through the Andes before descending to the Caribbean coast to the Tayrona National Park and charming and historic Cartagena. Along the way, you'll see Chicamocha Gorge, tour an authentic coffee hacienda, and hike to the lost stone city of El Pueblito.
0
Magdalena River, Colombia

Wonders of Colombia

Barranquilla to Cartagena
8 Days from $3,839
Immerse in Colombia's wonders on this 8-day cruise along the Magdalena River aboard AmaMagdalena. Explore Palenque, the first free city, and vibrant Getsemaní in Cartagena. Discover the fusion of cultures, music, and art that shape the country.
0
Mompox, Colombia

Wonders of Colombia

Cartagena - Barranquilla
8 Days from $3,839
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
0
Gaze at the balconies overlooking the breathtaking cathedral in Cartagena, Colombia

Just Drifting Along

Willemstad - Panama
9 Days from $8,565
Set sail on a 9-day cruise aboard the Sea Cloud Spirit, exploring the ABC islands, including Curacao's UNESCO-listed Willemstad and Aruba's colorful Oranjestad. Visit Cartagena's historic colonial streets, relax at sea, and end your journey in Panama's San Blas Archipelago and Colon.
0
San Pedro Claver Plaza, Cartagena

Colombia Highlights

Bogota to Cartagena
9 Days from $2,421
Enjoy a complete 9-day tour discovering the highlights of Colombia. Dance the salsa and explore the city of Bogota, visit the Wax Palm reserve in Salamina, and taste the best coffee in Manizales. Finally, discover the rich culture preserved in Cartagena. Visit multiple parts of Colombia and see the best that each place has to offer.
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6 Top-Rated Cartagena Cruise Ships for 2025-2026

Royal Clipper exterior

Royal Clipper

The Royal Clipper is the largest full-rigged sailing ship in the world, carrying just 227 privileged guests aboard. She offers the ultimate tall ship sailing experience, balancing the grandeur, adventure, and tradition of sailing with the superb service, amenities, and accommodations of the finest modern yacht. .
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Star Flyer/Star Clipper Exterior

Star Clipper

Star Clipper is a 170-passenger vessel designed to provide a unique traveling experience unlike any other cruise vacation. Step aboard and discover a new age of sail, where the traditions of the past are happily married to the comforts and amenities of the present day.
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Sea Cloud Spirit

Sea Cloud Spirit

Sea Cloud Spirit is a modern and elegant windjammer with occupancy for 136 guests and a crew of 85. It gives you an amazing opportunity of traveling with a high comfort level and enjoying the best panorama views.
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Mompox, Colombia

MS AmaMagdalena

Step aboard AmaWaterways' newly designed AmaMagdalena, a 60-passenger river cruise ship offering luxury, including a heated pool, fitness room, a restaurant, and al fresco dining. Enjoy stunning views of Colombia's Magdalena River from your amenity-filled twin-balcony stateroom.
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MS AmaMelodia - Artist's Rendition

MS AmaMelodia

Sail in luxury along Colombia’s Magdalena River aboard the AmaMelodia, a 64-passenger ship designed for optimal views. Enjoy your spacious stateroom with twin balconies, ranging from 237 to 306 square feet. Savor Latin American and Western cuisine in the Main Restaurant or al fresco, and enjoy live music each evening in the Main Lounge.
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National Geographic Quest

National Geographic Quest

The National Geographic Quest is a state-of-the-art expedition ship accommodating 100 guests in 5 different categories of fully equipped cabins. It is fully stabilized for cruising unique polar passages and wonderful tropical landscapes while providing comfort and adventure in every journey.
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Cartagena Travel Guide

Get stunning views of historic Cartagena

10 Best Things to Do in Cartagena

Whether you are a history enthusiast, a beach lover, a foodie, or a family looking for an enriching vacation, Cartagena has something special for everyone. Let's explore the top 10 things to do and see in this captivating city.
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The Rock of Guatape

Colombia Overview

Explore Colombia, a land of unspoiled beaches, lost ruins, and hospitable local culture. One of the most bio-diverse countries in the world, adventure travel enthusiasts can find great options to play and explore throughout. Colombia is still fairly undiscovered as a destination, so travelers should take the opportunity to visit before the influences of tourism occur.
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Balconies in Cartagena

Colombia FAQs

Planning a trip to Colombia can result in a lot of questions. Our FAQ article answers the most common ones asked by our travelers. From what the food is like to packing suggestions, this will hopefully help you feel better prepared for your Colombia adventures!
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Sunset over Cartagena

Colonial Cities of Colombia

Some of Latin America’s most beautiful colonial towns are found in Colombia. This guide highlights a few of these charming cities, including Bogota, Cartagena and Medellin. Travelers can walk among churches, cathedrals, and homes reminiscent of the past. Experience an untouched side of Colombia by visiting the country's colonial towns.
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