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Sail the turquoise waters of the Caribbean on these 10 top Colombia cruises for 2025 and 2026. Discover the walled city of Cartagena, port town Santa Marta, and the magical Islas de San Bernardo Some of the activities on our Colombia small ship cruises include snorkeling, hiking, and wildlife observation. Let your expert local English-speaking guides show you the hot spots and the off-the-beaten-path hidden gems in Colombia and the Caribbean coast. We work with only the best small ships that carry under 500 guests, ensuring an intimate and exclusive experience. Our Colombia cruises range from $3,339 to $21,660 for cruises of 8 to 15 days. Contact one of Adventure Life's Colombia cruise specialists for assistance to match you with the perfect small cruise ship for your next vacation. 
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Ruins at the Fortress of Santiago
from $4,840
EXPLORE

Natural Sanctuaries & Heritage of the Caribbean

Willemstad - Colon - 8 Day Itinerary aboard Le Champlain
  • See sites in Cartagena & Willemstad
  • Explore Santa Marta & Sierra Nevada
  • Discover San Blas Islands' beaches
  • Visit and explore Fort San Lorenzo
  • Witness wildlife and ecosystems
Starts / Ends
Willemstad / Colon
Activities
Snorkeling, Archaeological Site Visits, Village Visits, Hiking
Activity Level
Variable
Explore the Caribbean on this 8-day Natural Sanctuaries & Heritage of the Caribbean cruise from Willemstad to Colon aboard the Le Champlain. Walk through UNESCO-listed cities, snorkel in the San Blas Islands, and meet the Kuna people. Visit Santa Marta’s mountains and the Fort San Lorenzo in Panama. Discover coral reefs, mangroves, and wildlife.
Cruise Details
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Mompox, Colombia
from $3,339
EXPLORE

Magic of Colombia - Cruise Only

Barranquilla - Cartagena - 8 Day Itinerary aboard MS AmaMagdalena
  • Discover Mompox’s colonial treasure
  • Visit San Felipe Castle’s fortress
  • Explore Nueva Venecia’s village
  • Walk Cartagena’s historic city
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Set sail on an 8-day river cruise through Colombia's "Land of a Thousand Rhythms" aboard the MS AmaMagdalena. Enjoy vibrant Latin music, exclusive Carnaval performances, delicious coffee, and the rich culture and wildlife along the Magdalena River.
Cruise Details
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Magdalena River, Colombia
from $3,839
EXPLORE

Wonders of Colombia - Cruise Only

Cartagena - Barranquilla - 8 Day Itinerary aboard MS AmaMagdalena
  • Explore vibrant Getsemani Cartagena
  • Discover historic Palenque town
  • Tour scenic Calamar by bicycle taxi
  • Witness gold artistry in Mompox
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Sail the majestic Magdalena River on an 8-day cruise aboard the MS AmaMagdalena. Experience Colombia’s vibrant rhythms, rich history, and lively culture as you explore Palenque, Cartagena, and beyond.
Cruise Details
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Mompox, Colombia
from $3,839
EXPLORE

Wonders of Colombia

Cartagena - Barranquilla - 8 Day Itinerary aboard MS AmaMelodia
  • Explore ancient ruins and markets
  • Visit Bocas de Cenizas and museum
  • Enjoy Columbian nature and wildlife
Starts / Ends
Cartagena / Cartagena
Activities
Wildlife Viewing, Festival Visits
Activity Level
Variable
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
from $4,350
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends
Bridgetown / Balboa
Activity Level
Variable
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
Cruise Details
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The vivid colors of the San Blas Islands
from $4,350
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Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Explore Balboa’s colonial charm
  • Transit Panama’s iconic canal
  • Discover San Blas culture
  • Enjoy Aruba’s clear waters
Starts / Ends
Balboa / St. John's
Activity Level
Variable
Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.
Cruise Details
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The vivid colors of the San Blas Islands
from $4,240
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Barbados to Panama

Bridgetown - Balboa - 15 Day Itinerary aboard Star Clipper
  • Explore Bridgetown’s heritage
  • Discover St. George’s coastal views
  • Admire Kralendijk’s marine life
  • Wander Willemstad’s streets
Starts / Ends
Bridgetown / Balboa
Activities
Small Ship Sailing, Local Market Visits
Activity Level
Variable
Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.
Cruise Details
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Zapatilla Cay, Panama
from $6,741
Save 20%
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends
Panama City / Cartagena
Activity Level
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, San Bernardo Archipelago, and more.
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Traditional Maracas in Colombia
from $3,839
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Magic of Colombia

Barranquilla - Cartagena - 8 Day Itinerary aboard MS AmaMelodia
  • Experience Carnaval of Barranquilla
  • Visit Nueva Venecia
  • Discover the picturesque Cienega
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Embark on an 8-day cruise from Barranquilla to Cartagena aboard the AmaMelodia and experience the allure of Colombia. Discover the rich culture and traditions of San Agustin, Mompox, and La Dorada, and indulge in Colombia's famous coffee. Encounter the country's unique flora and fauna as you journey through this diverse and captivating land.
Cruise Details
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Mountains by the ocean in St Lucia
from $8,490
EXPLORE

Panama, Colombia & Caribbean Islands

Colon to Fort-de-France - 13 Day Itinerary aboard Le Champlain
  • Sail through the Central America.
  • See San Blas, Bonaire & Grenadines
  • Experience swim and snorkel.
  • Learn traditions of the Kuna people
  • Dive with an experienced instructor
Starts / Ends
Colon / Fort de France
Activities
Land & Sea Exploration
Activity Level
Variable
Join Le Bellot for an exceptional 13-day cruise sailing from Colón to Fort-de-France. This itinerary gives you the opportunity to appreciate the richness and diversity of Afro-Caribbean cultures, an azure blue sky, and white-sand beaches. Visit stunning ports, including Portobelo, Cartagena, Santa Marta, Mayreau Island, and Soufriére.
Cruise Details
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