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Mississippi River, St. Paul Minnesota

Top Mississippi River Trips & Tours in November 2025

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Discover Mississippi River in November 2025 on one of these 6 tours hand-selected by the travel experts at Adventure Life. Explore the best of New Orleans, Baton Rouge, Natchez, Vicksburg, and St. Francisville during November 2025 as you enjoy river cruises, urban exploration, cruises, cultural, and archaeological site visits. Prices for trips in November 2025 range from $3,475 to $11,200 for a vacation of 8 to 9 days. Choose any of the below 6 itineraries in November 2025 and customize it when you contact one of Adventure Life's expert Mississippi River trip planners.
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    • Mississippi River
Wander through the historic French Quarter
$3,999
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
The Lower Mississippi overflows with charm, history and hospitality. Wander historic estates, and visit notable Civil War sites. Explore the bustling French-influenced port cities of New Orleans and Baton Rouge. Sway to the tempos of Dixieland jazz, gospel and blues. Savor gourmet Cajun and Creole …
Cruise Details
0
Visit historic Memphis, Tennessee
$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Symphony from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Melody from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
$4,295
Savings
EXPLORE

Lower Mississippi River Cruise

9 Day Itinerary aboard American Splendor
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a 9-day Lower Mississippi River cruise aboard the American Splendor from Memphis to New Orleans. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Sail through cities like Vicksburg and Natchez each offering unique insights …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
$3,475
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Board American Heritage for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
Explore historic New Orleans
$4,190
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Melody
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Board American Melody for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
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