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Mississippi River, St. Paul Minnesota

Top Mississippi River Trips & Tours in April 2025

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Discover Mississippi River in April 2025 on one of these 6 tours hand-selected by the travel experts at Adventure Life. Explore the best of New Orleans, Baton Rouge, Natchez, Vicksburg, and Memphis during April 2025 as you enjoy cruises, river cruises, urban exploration, cultural, and archaeological site visits. Prices for trips in April 2025 range from $3,475 to $12,815 for a vacation of 8 to 12 days. Choose any of the below 6 itineraries in April 2025 and customize it when you contact one of Adventure Life's expert Mississippi River trip planners.
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Visit historic Memphis, Tennessee
$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Symphony from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Melody from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
$4,295
Savings
EXPLORE

Lower Mississippi River Cruise

9 Day Itinerary aboard American Splendor
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a 9-day Lower Mississippi River cruise aboard the American Splendor from Memphis to New Orleans. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Sail through cities like Vicksburg and Natchez each offering unique insights …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
$3,475
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Board American Heritage for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
Visit historic Memphis, Tennessee
$7,275
Savings
EXPLORE

Mississippi Explorer

12 Day Itinerary aboard American Symphony
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends:
New Orleans / Memphis
Activities:
Adventure Options, Archaeological Site Visits, Urban Exploration
Activity Level:
Variable
Embark on a 12-day cruise aboard the American Symphony along the Mississippi River, discovering iconic sites and cultural treasures. Explore historic estates like Oak Alley and Houmas House, visit Baton Rouge's Old State Capitol and LSU Rural Life Museum, and uncover the charm of St. …
Cruise Details
0
Explore beautiful Nashville
$4,840
Savings
EXPLORE

Music Cities Cruise

Memphis, TN to Nashville, TN - 9 Day Itinerary aboard American Symphony
  • Explore Memphis
  • Discover Paducah
  • Experience Lake Barkley
  • Enjoy Nashville
Starts / Ends:
Memphis / Nashville
Activities:
Small Ship Cruises
Activity Level:
Variable
Embark on a 9-day cruise from Memphis to Nashville aboard the American Symphony. Traverse the mighty Mississippi, majestic Ohio, and scenic Cumberland rivers. Experience the charm of historic towns, immerse yourself in local music culture, and enjoy nightly entertainment onboard. Relax and take in …
Cruise Details
0
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