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Mississippi River Cruises

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Mississippi River
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Experience the mighty Mississippi River on one of Adventure Life's 14 River Cruises for 2025. Navigate through the heart of America on cruises ranging from 8 to 16 days days, immersing yourself in the cultural tapestry of the region. From the vibrant music scene in New Orleans to the historic charm of Natchez, these cruises offer a blend of luxury and Southern hospitality that will leave you enchanted. Explore charming river towns, indulge in delicious Southern cuisine, and witness the diverse wildlife along the riverbanks. Join us on a trip to discover the iconic Mississippi River and its unparalleled beauty. Contact one of our award-winning river cruise experts for help planning your next seamless trip.
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View the iconic arch when you visit St. Louis, gateway to the west
from$12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Variable
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
Wander through the historic French Quarter
from$3,499
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, Cooking Classes, Festival Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
The Lower Mississippi overflows with charm, history and hospitality. Wander historic estates, and visit notable Civil War sites. Explore the bustling French-influenced port cities of New Orleans and Baton Rouge. Sway to the tempos of Dixieland jazz, gospel and blues. Savor gourmet Cajun and Creole …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from$3,630
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Heritage
  • Experience Natchez’s beauty
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration
Activity Level:
Variable
Board American Heritage for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
Visit historic Memphis, Tennessee
from$5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Symphony from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
from$5,190
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Melody from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
View monuments from the Civil War in Mississippi
from$4,530
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a captivating 9-day cruise aboard the American Heritage from Memphis to New Orleans, navigating the mighty Mississippi River. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Vicksburg unfolds its Civil War history, Natchez …
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from$11,755
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends:
St. Paul / New Orleans
Activities:
Village Visits
Activity Level:
Variable
Embark on a 16-day cruise aboard American Serenade and begin by exploring St. Paul's art galleries and historic Summit Avenue. In La Crosse, enjoy Riverside Park and panoramic views from Grand Dad’s Bluff. Discover Dubuque, with its Victorian mansions and the Mississippi River Museum …
Cruise Details
0
Vicksburg Battlefield overlooking the Mississippi River
from$3,999
EXPLORE

Mississippi Delta Explorer

New Orleans - Memphis - 8 Day Itinerary aboard Viking Mississippi
  • Explore Darrow
  • Visit Natchez historic sites
  • Learn the history of Vicksburg
  • Culinary adventure of Mississippi
  • Know the history of rock 'n' roll
  • American South's Cultural Heritage
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
On this 8-day Mississippi Delta Explorer from New Orleans to Memphis aboard the Viking Mississippi, visit Darrow, the starting point for the grand historic homes of the Lower Mississippi, and explore towns along the river that highlight the history and culture of the American South. Discover …
Cruise Details
0
Mississippi River, St. Paul Minnesota
from$5,545
Savings
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Melody
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a cruise along the Upper Mississippi River, exploring St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's home, witness diverse landscapes, and enjoy expert-guided tours. Adapt to the river's character as you relax on lounges, decks, or …
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from$4,295
Savings
EXPLORE

Lower Mississippi River Cruise

9 Day Itinerary aboard American Splendor
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a 9-day Lower Mississippi River cruise aboard the American Splendor from Memphis to New Orleans. Explore Memphis' musical legacy and vibrant culture before cruising through days of enchanting river views. Sail through cities like Vicksburg and Natchez each offering unique insights …
Cruise Details
0
Vicksburg Battlefield overlooking the Mississippi River
from$4,530
Savings
EXPLORE

Lower Mississippi River Cruise

New Orleans - Memphis - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a 9-day cruise aboard the American Heritage from New Orleans to Memphis. Explore New Orleans with its culinary delights, music, and culture. Sail the Mississippi River, visit historic sites, and enjoy onboard entertainment. Explore plantations, museums, swamps, and antebellum homes. …
Cruise Details
0
Explore historic New Orleans
from$4,190
Savings
EXPLORE

Historic Mississippi River Cruise

New Orleans Roundtrip - 8 Day Itinerary aboard American Melody
  • Explore the antebellum of Natchez
  • Visit historic Civil War sites
  • Discover Oak Alley's historic charm
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Board American Melody for this 8-day cruise along the Mississippi River. Explore unique sites and attractions, admiring the beauty of the world on a roundtrip river cruise from New Orleans. Uncover the history of Oak Alley Plantation, Baton Rouge's dynamic blend of history and modernity, and …
Cruise Details
0
Explore beautiful Nashville
from$4,840
Savings
EXPLORE

Music Cities Cruise

Memphis, TN to Nashville, TN - 9 Day Itinerary aboard American Symphony
  • Explore Memphis
  • Discover Paducah
  • Experience Lake Barkley
  • Enjoy Nashville
Starts / Ends:
Memphis / Nashville
Activities:
Small Ship Cruises
Activity Level:
Variable
Embark on a 9-day cruise from Memphis to Nashville aboard the American Symphony. Traverse the mighty Mississippi, majestic Ohio, and scenic Cumberland rivers. Experience the charm of historic towns, immerse yourself in local music culture, and enjoy nightly entertainment onboard. Relax and take in …
Cruise Details
0
Mississippi River, St. Paul Minnesota
from$4,530
Savings
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Heritage
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a cruise along the Upper Mississippi River, exploring St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's home, witness diverse landscapes, and enjoy expert-guided tours. Adapt to the river's character as you relax on lounges, decks, or …
Cruise Details
0
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