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Vineyard underneath the Niederwald Monument, Rudesheim, Germany

Mainz Germany River Cruises

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At the confluence of the Rhine and Main rivers,  Mainz was home to the 15th century innovator Johannes Gutenberg, whose printing press revolutionized the world. When you visit this city on your Rhine River cruise, you'll learn more about the history of the press at the Gutenberg Museum. Just a few minutes stroll from the river port, spend some time strolling the ancient medieval avenues of this well-preserved town.medieval buildings, intriguing cobbled streets, Roman ruins, Baroque churches, charming restaurants and eclectic shops. This part of the Rhine is considered by many to be one of the most scenically beautiful sections, and features the famous Rock of Lorelei and the neighboring towns of Koblenz and Worms and is a one-day cruise from Strasbourg, France. Contact our experts today to start planning your trip!
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5 Best Rhine River Cruises to Mainz for 2025-2026

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1 Best Luxury Cruises to Mainz for 2025-2026

Trip NameFromDaysNext DepartureSummary
Rhine Holiday Markets$39998Nov 25, 2025Set sail on an 8-day festive cruise from Basel to Cologne aboard the S.S. Antoinette, exploring Switzerland, France, and Germany. Discover holiday …
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2 Best Rhine River Cruise Deals for 2025-2026

Trip NameSaveFromDaysNext DepartureSummary
Vineyards of the Rhine & MoselleSavings$33998Apr 2, 2025MS Amaprima hosts this exciting 8-day cruise along the Rhine and Moselle. Explore splendid Cologne with its magnificent dome and admire the …
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Rhine Castles & Moselle VineyardsCustom Label$1059011Jul 15, 2025Embark on an 11-day Rhine Castles & Moselle Vineyards Cruise from Amsterdam to Zurich on Emerald Sky. Discover landscapes adorned along the Rhine & …
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Mainz Travel Guide

Highlights of Mainz, Germany

Just a few minutes away from the dock you'll find a charming medieval city of great historic importance waiting to be explored. Don't miss these unique experiences:
  • Exploring the Gutenberg Museum - the pride and joy of Mainz is the museum dedicated to the Gutenberg press and the first printed pages of text in the form of the Gutenberg bible.
  • Tasting local wines with the locals in a half-timbered Altstadt tavern
  • St-Stephan-Kirche church would be yet another Gothic church if not for the spectacular blue stained glass windows made by Russian-Jewish artist Marc Chagall.
  • Museum für Antike Schifffahrt – The Museum of Ancient Seafaring contains the remains of several 5th century Roman warships found wrecked in the Rhine. Replicas were re-constructed based on these originals.  
Popular Destinations in Mainz, Germany
Some of the most popular destinations frequently visited on a trip to Mainz, Germany are:
  • The Mainz Cathedral
  • The Gutenberg Museum
  • Marktbrunnen 
  • Stephanskirche
  • Schillerplatz
  • Museum of Ancient Seafaring
  • Landesmuseum of archaeology, art and culture
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