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Top Rhine River Trips & Tours in May 2025

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Discover Rhine River in May 2025 on one of these 32 tours hand-selected by the travel experts at Adventure Life. Explore the best of during May 2025 as you enjoy Biking, Hiking, Wine Tasting, Village Visits, and Land & Sea Exploration. Prices for trips in May 2025 range from $3,299 to $24,990 for a vacation of 8 to 15 days. Choose any of the below 32 itineraries in May 2025 and customize it when you contact one of Adventure Life's expert Rhine River trip planners.
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Grossmunster Cathedral, Zurich
from $6,099
EXPLORE

Enchanting Rhine

12 Day Itinerary aboard MS Amaprima
  • Enjoy panoramic views of Zürich
  • Walk along Lucerne's famous streets
  • Visit the iconic Heidelberg Castle
  • Admire Amsterdam's beauty
Activity Level
Variable
After spending two nights in both Zurich and Lucerne, Switzerland, board the MS Amaprima on an exclusive 7-day Rhine River cruise through the historic old towns and big cities of Germany, the historic borderlands of Strasbourg, France, and finally to Amsterdam in the Netherlands.
Cruise Details
0
La Petite district in Strasbourg
from $3,299
EXPLORE

Rhine Getaway

Amsterdam to Basel - 8 Day Itinerary aboard Viking River Cruises
  • Explore the village of Kinderdijk
  • View the sites of Rüdesheim
  • Discover the Speyer Cathedral
  • Visit resplendent churches
Starts / Ends
Amsterdam / Basel
Activities
Urban Exploration
Activity Level
Variable
Explore one of Europe’s best-loved rivers, the Rhine, during this 8-day voyage. Discover the turreted fortresses, grand cathedrals, historic cities, medieval towns and spectacular scenery of the Middle Rhine - a UNESCO World Heritage Site. From Amsterdam to Basel, this journey reveals a rich landscape of beauty and culture.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $4,239
CLP
EXPLORE

Enchanting Rhine - Cruise Only

Basel - Amsterdam - 8 Day Itinerary aboard MS Amalucia
  • Explore Heidelberg's castle views
  • Savor Rudesheim's famed Riesling
  • Stroll Strasbourg's streets
  • Discover Breisach's scenic past
Starts / Ends
Basel / Amsterdam
Activities
Local Market Visits
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amalucia, exploring cities where rich history meets modern progress. Journey along the scenic Rhine, passing 40 castles, timeless traditions, and inspiring towns like Heidelberg, where Mark Twain wrote A Tramp Abroad.
Cruise Details
0
Cruise the rivers of Germany
from $8,190
2for1
EXPLORE

Jewels of the Rhine

Zurich - Amsterdam - 8 Day Itinerary aboard Emerald Sun
  • Visit a Black Forest village
  • Visit Heidelberg Castle
  • Take a walk to Heidelberg
  • Ride a cable car in Koblenz
Starts / Ends
Zurich / Amsterdam
Activity Level
Variable
From Zurich to Amsterdam, the Emerald Sun invites you on this mesmerizing 8-day Rhine River cruise, visiting Basel, Breisach, Cologne, Heidelberg, Koblenz, Mannheim, and Strasbourg. Each day, you can choose how you'd like to explore each of these historic cities, with chances for hiking, biking, and walking tours.
Cruise Details
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Explore Basel
from $5,899
EXPLORE

Castles along the Rhine

Basel - Amsterdam - 8 Day Itinerary aboard S.S. Victoria
  • Tour the capital of Alsatian wines
  • Enjoy a visit the Romanesque cathed
  • Visit the Marksburg Castle
  • Walk through Strasbourg
Starts / Ends
Amsterdam / Basel
Activities
Archaeological Site Visits
Activity Level
Variable
During this 8-day cruise from Basel to Amsterdam aboard the S.S. Victoria, cruise along the impressive Rhine River —Germany on one side, France on the other. Discover Alsace, whose dual French and German heritage has given it fabulous food and a winemaking tradition that goes back to the Romans.
Cruise Details
0
River through Koblenz Germany
from $3,382
EXPLORE

From Basel to Amsterdam: The Treasures of the Celebrated Rhine River

8 Day Itinerary aboard MS Symphonie
  • Visit the spectacular Rhine Falls
  • Enjoy a free morning in Breisach
  • Admire the wine-growing region
  • Explore the Gutenberg Museum
Starts / Ends
Basel / Amsterdam
Activity Level
Variable
Explore the enchanting waterways of the Rhine River aboard the comfortable MS Symphonie. Discover a mix of nature and culture on this 8-day voyage from the Three Countries Bridge to Holland, with stops at the Gutenberg Museum, the Strasbourg wine-growing region, and the Rhine Falls, as well as Cologne, Mainz, and Xanten.
Cruise Details
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Discover charming Heidelberg
from $8,190
2for1
EXPLORE

Jewels of the Rhine

Amsterdam-Basel - 8 Day Itinerary aboard Emerald Sky
  • Discover the charming Koblenz
  • Visit a Black Forest village
  • Discover the beauty of Strasbourg
  • Tour Heidelberg Castle
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Discover the Rhine region's architecture, history, and natural beauty on this delightful cruise from Amsterdam to Basel, Switzerland. Explore the Black Forest region, wander through Strasbourg, visit Cologne, and much more on this 8-day cruise aboard Emerald Sky.
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
from $4,239
CLP
EXPLORE

Captivating Rhine - Cruise Only

Amsterdam - Basel - 8 Day Itinerary aboard MS Amaviola
  • Cruise Amsterdam’s scenic canals
  • Discover Cologne’s Gothic beauty
  • Explore Dusseldorf’s vibrant charm
  • Sail the Rhine Gorge’s epic views
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Embark on an 8-day cruise from Amsterdam to Basel aboard the MS Amaviola, where picturesque vineyards and historic castles await. Discover charming towns like Strasbourg and Colmar, from Rudesheimer coffee to German beer, while enjoying local flavors.
Cruise Details
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Strasbourg
from $4,239
CLP
EXPLORE

Captivating Rhine - Cruise Only

Amsterdam to Basel - 8 Day Itinerary aboard MS AmaSiena
  • Take an Amsterdam canal tour
  • Enjoy bike tours and wine tastings
  • Hike up the Philosopher's Path
  • Join a panoramic tour of Strasbourg
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Sail from Amsterdam to Basel on an 8-day Rhine River cruise aboard the MS Amasiena, passing vineyard-clad hills and fairytale castles. Explore charming towns, savor local flavors, and experience the beauty of Alsace, the Black Forest, and beyond.
Cruise Details
0
Cochem town on the Mosel River, Germany
from $5,799
No SS
EXPLORE

The Rhine & Moselle (Northbound)

Basel - Amsterdam - 11 Day Itinerary aboard Avalon Imagery II
  • Explore Black Forest village
  • Visit Strasbourg's Gothic cathedral
  • Discover Heidelberg Castle ruins
  • Taste wine in Bernkastel
Starts / Ends
Basel / Amsterdam
Activities
Wine Tasting, Land & Sea Exploration
Activity Level
Variable
Embark on an 11-day cruise aboard the Avalon Imagery II. Explore the Rhine and Moselle Rivers, starting in Basel. Discover charming cities in Germany, France, and Amsterdam, exploring Breisach, Strasbourg, and the Rhine Gorge while enjoying wine tastings in Bernkastel and a canal cruise in Amsterdam.
Cruise Details
0
Stroll along the canals of Dusseldorf
from $5,238
EXPLORE

Active & Discovery on the Rhine with 2 Nights in Lucerne

Amsterdam to Lucerne - 10 Day Itinerary aboard Avalon Panorama
  • See Dusseldorf’s architecture
  • Cruise the scenic Rhine Gorge
  • Explore Strasbourg grand cathedral
  • Tour medieval village of Burkheim
Starts / Ends
Amsterdam / Lucerne
Activities
Hiking, Biking, Village Visits, Kayaking, Small Ship Sailing
Activity Level
Variable
Sail on a 10-day Rhine river cruise from Amsterdam to Lucerne on board Avalon Panorama. Explore Dusseldorf's avant-garde architecture and Old Town, and visit Koblenz and its stunning Rhine Gorge. Visit the grand cathedral and charming districts of Strasbourg, and enjoy a bike tour of the magical Black Forest in Breisach.
Cruise Details
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Cologne, Germany
from $4,239
CLP
EXPLORE

Captivating Rhine - Cruise Only

Amsterdam - Basel - 8 Day Itinerary aboard MS Amaprima
  • Cruise Amsterdam’s charming canals
  • Stroll Dusseldorf’s vibrant streets
  • Sail through the scenic Rhine Gorge
  • Taste wine in Rudesheim’s vineyards
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Embark on an 8-day Rhine River cruise aboard the MS Amaprima, passing vineyard-clad hills, fairytale towns, and historic castles. Explore Strasbourg, Colmar, and the Black Forest, then savor local flavors from Amsterdam to the Swiss Alps.
Cruise Details
0
Rhine Gorge
from $5,379
EXPLORE

Rhine & Moselle Fairytales - Cruise Only

12 Day Itinerary aboard MS Amaserena
  • Cruise to Cologne
  • Bike along the Rhine
  • Explore the Bundesbank Bunker
  • Visit Rüdesheim
Activity Level
Variable
Enjoy a 12-day voyage on the Rhine River! Pages from fairytales come to life as you find inspiration along the fabled castle-laden Rhine and its breathtaking tributary, the Moselle
Cruise Details
0
Explore Basel
from $6,099
EXPLORE

Enchanting Rhine

Zurich - Amsterdam - 12 Day Itinerary aboard MS Amacerto
  • Explore Zurich's vibrant history
  • Wander Strasbourg's streets
  • Visit Breisach's countryside
  • Cruise Rhine's stunning castles
Starts / Ends
Zurich / Amsterdam
Activity Level
Variable
Set sail from Zurich to Amsterdam on a 12-day Rhine cruise aboard the MS Amacerto. Discover vibrant cities, storied towns, and timeless traditions amid stunning castles and scenic riverbanks.
Cruise Details
0
Cologne, Germany
from $6,929
EXPLORE

Captivating Rhine

14 Day Itinerary aboard MS Amaprima
  • Explore Heidelberg’s medieval charm
  • Wander Strasbourg’s storybook lanes
  • Discover Colmar’s colorful beauty
  • Hike in the mystical Black Forest
Activity Level
Variable
Sail the legendary Rhine on a 14-day cruise with stays in Lucerne and Zurich aboard the MS Amaprima. From Amsterdam’s canals to the Swiss Alps, explore vineyard-clad hills, fairytale towns, and historic cities along this enchanting river.
Cruise Details
0
Visit beautiful and historic Strasbourg
from $6,719
EXPLORE

Rhine Castles & Swiss Alps

13 Day Itinerary aboard MS Amaserena
  • Discover Amsterdam’s charming canal
  • Explore Cologne’s historic treasure
  • Cruise Rhine Gorge’s castles
  • Visit Rudesheim’s scenic vineyards
Starts / Ends
Amsterdam / Basel
Activity Level
Variable
Sail aboard the MS Amaserena on a 13-day cruise through Europe, featuring Amsterdam’s canals, Germany’s Rhine Gorge castles, France’s Alsace charm, and Italy’s glamorous Lake Como. Explore five countries and iconic landmarks.
Cruise Details
0
Strasbourg
from $6,929
EXPLORE

Captivating Rhine

14 Day Itinerary aboard MS Amaviola
  • Join a guided bike tour
  • Visit Speyer
  • Enjoy Parc de l’Orangerie
  • Explore the Black Forest
Activity Level
Variable
From Amsterdam’s colorful canals to the majestic Swiss Alps, enjoy a 14-day exploration of the Rhine Valley, starting with two days in Amsterdam followed by 7 nights aboard the MS Amaviola, and concluding with four nights in Switzerland between Lucerne and Zurich. Sample the local brews of beer and coffee with chances to hike and bike as well!
Cruise Details
0
Rhine Gorge
from $6,929
EXPLORE

Captivating Rhine

Amsterdam - Zurich - 14 Day Itinerary aboard MS Amalucia
  • Taste wines in Rudesheim’s vineyard
  • Bike through charming Strasbourg
  • Explore Dusseldorf’s vibrant street
  • Wander Colmar’s fairytale alleys
Starts / Ends
Amsterdam / Zurich
Activity Level
Variable
Sail the legendary Rhine on this 14-day river cruise aboard the MS Amalucia, where vineyard-clad hills and fairy-tale castles set the scene. Explore charming Alsace, historic German towns, and Amsterdam’s canals, savoring local flavors and unforgettable landscapes.
Cruise Details
0
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