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Top Rhine River Trips & Tours in September 2025

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Discover Rhine River in September 2025 on one of these 23 tours hand-selected by the travel experts at Adventure Life. Explore the best of Amsterdam, Cologne, Strasbourg, Basel, and Rudesheim during September 2025 as you enjoy cruises, river cruises, wine tasting, biking, and hiking. Prices for trips in September 2025 range from $2,199 to $82,500 for a vacation of 7 to 16 days. Choose any of the below 23 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert Rhine River trip planners.
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Stop in beautiful Basel, Switzerland
$4,099
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Castles along the Rhine

Basel - Amsterdam - 8 Day Itinerary aboard S.S. Antoinette
  • Explore Strasbourg's cobbled street
  • Wander Speyer’s Old Town
  • Visit medieval Marksburg Castle
  • Explore Cologne's historic center
Starts / Ends:
Basel / Amsterdam
Activities:
Archaeological Site Visits, Biking, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise from Basel to Amsterdam aboard the S.S. Antoinette. Explore the enchanting beauty of the Rhine, with Germany on one side and France on the other. Discover Alsace’s rich culinary and winemaking heritage, marvel at historic castles like Rheinstein, and visit charming …
Cruise Details
0
La Petite district in Strasbourg
$2,199
EXPLORE

Rhine Getaway

Amsterdam to Basel - 8 Day Itinerary aboard Viking Cruises
  • Explore the village of Kinderdijk
  • View the sites of Rüdesheim
  • Discover the Speyer Cathedral
  • Visit resplendent churches
Starts / Ends:
Amsterdam / Basel
Activities:
River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Board your ship in Amsterdam for a fantastic 8-day adventure, where you will explore one of Europe’s best-loved rivers, the Rhine. Discover the turreted fortresses, grand cathedrals, historic cities, medieval towns and spectacular scenery of the Middle Rhine - a UNESCO World Heritage Site. …
Cruise Details
0
Ehrenfels Castle on Rhine River near Rudesheim
$2,599
Savings
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The Enchanting Rhine - From Basel to Amsterdam

8 Day Itinerary aboard MS Amalucia
  • Join a panoramic tour of Strasbourg
  • Hike up the Philosopher's Path
  • Bike along the Rhine
  • Tour the canals of Amsterdam
Starts / Ends:
Basel / Amsterdam
Activities:
River Cruises, Small Ship Cruises
Activity Level:
Variable
This 8-day journey reveals the hidden treasures and magnificent gems of the Rhine, one of Europe´s most fascinating rivers. Explore splendid cities and charming villages nestled between Basel and Amsterdam, home to timeless traditions that still remain intact. Enjoy daily excursions with a …
Cruise Details
0
Cruise the rivers of Germany
$6,790
EXPLORE

Jewels of the Rhine

Zurich - Amsterdam - 8 Day Itinerary aboard Emerald Sun
  • Visit a Black Forest village
  • Visit Heidelberg Castle
  • Take a walk to Heidelberg
  • Ride a cable car in Koblenz
Starts / Ends:
Zurich / Amsterdam
Activities:
Biking, Hiking, River Cruises, Village Visits
Activity Level:
Variable
Board the ship in Basel, Switzerland. First to explore in the list is the Black Forest, known for its cuckoo clocks and the live oompah bands. Here, visit a Black Forest village or hike passing under an idyllic canopy of evergreens. In Strasbourg, be amazed by the ornate beauty of Maison Kammerzell …
Cruise Details
0
Explore Basel
$4,699
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Castles along the Rhine

8 Day Itinerary aboard S.S. Victoria
  • Tour the capital of Alsatian wines
  • Enjoy a visit the Romanesque cathed
  • Visit the Marksburg Castle
  • Walk through Strasbourg
Starts / Ends:
Amsterdam / Basel
Activities:
Archaeological Site Visits, Biking, Small Ship Cruises, Village Visits
Activity Level:
Variable
This 8-day voyage aboard the River Empress is an ideal holiday for castle lovers. Sail along the Rhine river and marvel at castles that were once mighty fortresses and get an insider’s look at one of the only castles on the Rhine that has never been destroyed, Marksburg Castle. Visit historic …
Cruise Details
0
River through Koblenz Germany
$2,300
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From Basel to Amsterdam: The Treasures of the Celebrated Rhine River

8 Day Itinerary aboard MS Symphonie
  • Visit the spectacular Rhine Falls
  • Enjoy a free morning in Breisach
  • Admire the wine-growing region
  • Explore the Gutenberg Museum
Starts / Ends:
Basel / Amsterdam
Activities:
Biking, Hiking, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
From Basel to Amsterdam, embark on an authentic and historically rich cruise on the MS Symphonie. Admire the Rhine Falls before exploring historic landmarks in locations like Haarlem or Colmar and its Unterlinden museum. You can stroll to the Arnhem Open Air Museum, which tells a story from a …
Cruise Details
0
Discover charming Heidelberg
$7,390
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Jewels of the Rhine

Amsterdam-Basel - 8 Day Itinerary aboard Emerald Sky
  • Discover the charming Koblenz
  • Visit a Black Forest village
  • Discover the beauty of Strasbourg
  • Tour Heidelberg Castle
Starts / Ends:
Amsterdam / Basel
Activities:
River Cruises, Small Ship Cruises
Activity Level:
Variable
Join an enchanting cruise along the beautiful and storied Rhine river. Begin your journey in Amsterdam, and stop at UNESCO World Heritage-listed Cologne Cathedral. Explore the town of Koblenz and visit the twin-towered façade of the Church of Our Lady and the German Corner. A wine tasting …
Cruise Details
0
Strasbourg
$2,899
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Captivating Rhine - Cruise Only

Amsterdam to Basel - 8 Day Itinerary aboard MS AmaSiena
  • Take an Amsterdam canal tour
  • Enjoy bike tours and wine tastings
  • Hike up the Philosopher's Path
  • Join a panoramic tour of Strasbourg
Starts / Ends:
Amsterdam / Basel
Activities:
Biking, Hiking, River Cruises, Wine Tasting
Activity Level:
Variable
Spend 8 days cruising along the romantic Rhine through four European countries aboard the luxurious MS Amasiena. On this journey, explore the famous canals of Amsterdam. Explore Düsseldorf's rich culture and architecture through walking or bike tours, then relax on board as you cruise the …
Cruise Details
0
Cochem
$3,899
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Rhine & Moselle Splendors - Cruise Only

8 Day Itinerary aboard MS Amacerto
  • Explore historical Trier
  • Discover the Reichsburg Castle
  • Visit Rüdesheim on a gondola ride
  • Enjoy the beautiful Neckar Valley
Starts / Ends:
Luxembourg / Basel
Activities:
Biking, Hiking, Urban Exploration, Wine Tasting
Activity Level:
Variable
Begin your 8-day river cruise aboard the MS Amacerto along two of Europe’s most alluring rivers, the Rhine and Moselle. Step into the pages of a fairytale in Cochem and Strasbourg. Marvel at the Palace Gardens of Schwetzingen, the only park in Europe that still retains its original …
Cruise Details
0
Cochem town on the Mosel River, Germany
$5,599
Savings
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The Rhine & Moselle (Northbound)

Basel - Amsterdam - 11 Day Itinerary aboard Avalon Imagery II
  • Explore Black Forest village
  • Visit Strasbourg's Gothic cathedral
  • Discover Heidelberg Castle ruins
  • Taste wine in Bernkastel
Starts / Ends:
Basel / Amsterdam
Activities:
River Cruises, Small Ship Cruises, Wine Tasting
Activity Level:
Variable
Embark on an 11-day cruise aboard the Avalon Imagery II. Cruise along the Rhine and Moselle Rivers, starting in Basel, Switzerland, and visiting remarkable cities in Germany, France, and Amsterdam. Explore Breisach, the gateway to Germany's enchanting Black Forest, then journey to Strasbourg to …
Cruise Details
0
Koblenz at night
$9,090
EXPLORE

Rhine Highlights

8 Day Itinerary aboard Scenic Opal
  • Wander Amsterdam’s canals
  • Cruise Europe’s beautiful rivers
  • Admire Cologne's cathedral
  • Discover historic Heidelberg
Starts / Ends:
Amsterdam / Basel
Activities:
Hiking, River Cruises, Urban Exploration
Activity Level:
Variable
Discover some of the most charming towns of Europe as you cruise along the Rhine. Wander the winding canals of Amsterdam, admire Cologne’s sky-scraping cathedral, explore Heidelberg Castle, relax in the spa resort town of Baden-Baden and visit romantic Strasbourg. Throughout your journey, …
Cruise Details
0
Historic Zurich with River Limmat, Switzerland
$5,659
EXPLORE

The Enchanting Rhine

12 Day Itinerary aboard MS Amastella
  • Join a city tour of Zurich
  • Bike along Strasbourg
  • Admire Amsterdam's beauty
  • Visit the iconic Lion Monument
Activities:
Biking, Hiking, River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Discover the wonders of the Rhine River on this magnificent 8-day cruise. Start with a city tour of picturesque Zürich, followed by two nights in this magical city, then enjoy a scenic drive to Vitznau on Lake Lucerne for a second two-night stay. Board the MS Amastella and visit Strasbourg in …
Cruise Details
0
Visit beautiful and historic Strasbourg
$5,139
EXPLORE

Rhine Castles & Swiss Alps

13 Day Itinerary aboard MS Amaserena
  • Explore Amsterdam
  • Visit Cologne Cathedral
  • Cruise through the Rhine Gorge
  • Admire views of the Lake Como
Starts / Ends:
Amsterdam / Basel
Activities:
Hiking, Small Ship Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Start by exploring the canal-laden city of Amsterdam, with its neat rows of buildings and rich history. Then it’s off to Germany, where you’ll discover not only the grand city of Cologne but charming villages like the winemaking hamlet of Rüdesheim and the university town of …
Cruise Details
0
Cochem town on the Mosel River, Germany
$10,725
EXPLORE

Classic Cruise – Germany & Luxembourg

7 Day Itinerary aboard La Nouvelle Etoile
  • Visit the 'Queen of German Castles'
  • Tour Germany’s oldest town
  • Finish the cruise in Luxembourg
  • Enjoy superb European wines
Activities:
Local Market Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Join an exciting and breathtaking 7-day cruise aboard La Nouvelle Etoile sailing through Germany & Luxembourg where you will find some of the historical places that will take you back in time. Visit Burg Eltz, the 12th Century Queen of German Castles. Tour Trier, Germany’s oldest town and …
Cruise Details
0
Schloss Neuschwanstein overlooks the green countryside
$4,239
Savings
EXPLORE

Europe's Rivers & Castles - Cruise Only

Nuremberg - Luxembourg - 8 Day Itinerary aboard MS Amacerto
  • Cruise Europe's rivers
  • Explore towns and villages
  • Visit Rothenburg
  • Visit a UNESCO World Heritage Site
  • Enjoy wines from Rheingau region
  • Try Bamberg’s smoked beer
Starts / Ends:
Nuremberg / Luxembourg
Activities:
Biking, River Cruises, Wine Tasting
Activity Level:
Variable
On this 8-day Europe's Rivers & Castles Cruise from Nuremberg to Luxembourg aboard MS Amacerto, travel from the winding Main River to the UNESCO-listed Upper Middle Rhine Valley, lined with castles, and the vineyard-covered hills of the Moselle. Visit the villages of Bernkastel, Cochem, and …
Cruise Details
0
Explore Cologne
$11,190
EXPLORE

Splendours of Europe

Amsterdam to Budapest - 15 Day Itinerary aboard Emerald Sun
  • Explore the Dutch Golden Age
  • Pass the infamous Lorelai Rock
  • Visit Würzburg
  • Discover Vienna’s famous sights
Starts / Ends:
Amsterdam / Budapest
Activities:
Small Ship Cruises, Village Visits
Activity Level:
Variable
Embark on a 15-day Splendour of Europe cruise from Amsterdam to Budapest aboard Emerald Sun. Explore Amsterdam's picturesque canals, cafés, and art galleries. Visit the cathedral city of Cologne is one of the oldest cities in Germany and the largest on the Rhine. Admire hilltop castles, …
Cruise Details
0
Visit castle ruins in the German countryside
$4,499
EXPLORE

Grand European Tour

Amsterdam to Budapest - 15 Day Itinerary aboard Viking Cruises
  • Discove the Dom,Germany’s cathedral
  • Explore Marksburg Castle
  • Visit the Bishops’ Residenz
  • View Germany’s oldest restaurant
Starts / Ends:
Amsterdam / Budapest
Activities:
Biking, Hiking, River Cruises, Urban Exploration
Activity Level:
Variable
Embark on your ship in Budapest and discover the Rhine Valley vistas from a 900-year-old castle. Sample the food and wine of Austria’s Wachau Valley. Learn the Viennese waltz and linger in Budapest’s Café Gerbeaud. Indulge all your senses on this 15-day journey spanning the best …
Cruise Details
0
Budapest, the capital city of Hungary
$6,999
EXPLORE

European Jewels

Budapest - Amsterdam - 16 Day Itinerary aboard River Duchess
  • Experience Frankfurt’s
  • Explore Nuremberg
  • Enjoy Rudesheim
  • Discover Vienna
Starts / Ends:
Budapest / Amsterdam
Activities:
Biking, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on a 16-day cruise from Budapest to Amsterdam aboard the River Duchess through four countries along three iconic rivers, immersing yourself in Europe's majestic art, architecture, music, and history. From the exotic charm of Budapest to Vienna's imperial elegance and the towering …
Cruise Details
0
1-18 of 23 Results
TrustScore 4.8 | 377 reviews
TrustScore 4.8 of 5
total score
Based on 377 reviews on
review score
6 hours ago
Jessica was wonderful! She made every effort to ensure our trip was just what we wanted.
Celine Krafft
review score
6 hours ago
Erin was easy to work with and very helpful. She was patient and helped us figure out the adventure tour we were hoping for in Belize. Can’t wait to go on this trip!
Sam Wedll
review score
1 day ago
Jason has gone above and beyond. We have so much appreciation for him!
Jackie Smedley
review score
1 day ago
My travel planner, Jeff, who is on top of his field (based on travel industry awards), is a highly professional, very effective and, at the same time, personally nice individual. What was also critical to me is that he has a first hand experience traveling in the region that I am going to. On top of that, the customer relations director, Sarah, has personally followed up to make sure I'm happy.
alex shaykis
review score
2 days ago
Very well organiced. Great communication Easy to handle website for required docs to file . Pleasant Experience
Nancy Kaierle

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