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Top Mekong River Trips & Tours in October 2025

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Discover Mekong River in October 2025 on one of these 29 tours hand-selected by the travel experts at Adventure Life. Explore the best of during October 2025 as you enjoy Village Visits, Local Market Visits, Archaeological Site Visits, Biking, and Wildlife Viewing. Prices for trips in October 2025 range from $990 to $23,290 for a vacation of 5 to 16 days. Choose any of the below 29 itineraries in October 2025 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
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    • Mekong River
The beautiful Vinh Trang temple near My Tho
from $4,299
EXPLORE

Mekong River - Upstream - High water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Cooking Classes
Activity Level
Variable
Experience the Mekong River during the high water season on this 8-day cruise on The Jahan. This expedition takes you from Saigon to Siem Reap, allowing you to discover the lower Mekong and its fascinating towns while learning about their diverse cultures and rich history.
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $3,788
EXPLORE

Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Explore rural villages
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Explore floating markets
  • Discover cultures of Mekong Delta
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on this 8-day high river expedition on the Jayavarman and experience the Mekong River as it flows from Saigon to Siem Reap. Explore the lower Mekong and discover the diverse cultures and historical significance of the towns along its course.
Cruise Details
0
Phnom Penh Royal Palace complex
from $2,124
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Sunset over the Mekong River
from $3,788
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.
Cruise Details
0
Phnom Penh Royal Palace complex
from $1,956
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Floating Market in Cai Be
from $4,299
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Join this 8-day Mekong River cruise during the high water season from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong delta. Stop in charming port towns and immerse yourself in the city's culture and history.
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,956
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
Cruise Details
0
Floating village in Southeast Asia
from $2,292
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
From Siem Reap to Phnom Penh, join this 5-day High Water Mekong river cruise aboard the Jayavarman and journey through the vast Mekong Delta to explore the historic pre-Angkorian temples and Cambodian culture.
Cruise Details
0
Traditional mat-making
from $2,124
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
  • Experience Binh Thanh Island
  • Explore My An Hung Village
  • Discover Tan Chau
  • Experience Cao Dai
Starts / Ends
Phnom Penh / My Tho
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
Cruise Details
0
Royal Palace and Silver Pagoda
from $2,502
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Join this 5-day high water river cruise aboard the Jahan from Siem Reap to Phnom Penh, and travel across the mighty Mekong Delta to discover the ancient pre-Angkorian temples and Cambodian culture.
Cruise Details
0
Cycling along the bridge
from $1,475
EXPLORE

Cycling the Mekong Delta

Vietnam Small Group Tour - 8 Day Itinerary
  • Explore Ho Chi Minh City
  • See the floating market in Cai Be
  • Visit the Khmer templ in Tra Vinh
  • Explore Can Tho's charming villages
  • See the rice paddies in Long Xuyen
  • Discover Chau Doc' diverse culture
Starts / Ends
Ho Chi Minh City / Ho Chi Minh City
Activities
Biking, Local Market Visits, Archaeological Site Visits, Homestays, Urban Exploration
Activity Level
Moderate
Discover the heart of Vietnam in the enchanting Mekong Delta on an unforgettable 8-day small group cycling adventure from Ho Chi Minh City to Chau Doc. Immerse yourself in scenic landscapes and vibrant cultures as you pedal through picturesque paths. Uncover the beauty of traditional villages, witness the rhythm of local life, and savor the flavors of authentic cuisine.
Tour Details
0
Everyday life in Vietnam
from $3,439
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
Cruise Details
0
The beautiful Angkor Wat
from $10,290
NO SS
EXPLORE

Mekong Expedition - Siem Reap to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
  • Visit Prek Toal Core Bird Reserve
  • Sail to floating village Chhnok Tru
  • See Cambodia's capital & sights
  • Meet & interact with locals
Activity Level
Variable
This 8-day cultural cruise aboard the Aqua Mekong takes you from Siem Reap, Cambodia to Ho Chi Minh City, Vietnam, stopping at Tonle Sap Lake and other local destinations of interest along the Mekong River. You will visit Prek Toal Core, sail into Chhnok Tru, a true floating village, and see Cambodia's capital by motorized tuk-tuk.
Cruise Details
0
Kampong Chhnang
from $6,418
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Starts / Ends
Ho Chi Minh City / Hanoi
Activities
Land & Sea Exploration
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
Cruise Details
0
Vietnam's bird sanctuary
from $10,290
NO SS
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong
  • Experience vibrant markets
  • Enjoy touring Cambodia's capital
  • Visit Long Son Pagoda
  • Explore Prek Toal Core Bird Reserve
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Board the Aqua Mekong for an unforgettable 8-day cruise up the Mekong River from Saigon, Vietnam to Siem Reap, Cambodia, with stops in Phnom Penh and Tonle Sap Lake, among other highlights of the Indochina peninsula. Biking, hiking, cultural immersion, market visits, and cooking classes highlight the cruise.
Cruise Details
0
Sanctuary Spa
from $990
EXPLORE

Farm House Resort and Spa Extension

4 Day Itinerary
  • Discover Kampong Chhnang
  • Relax at the Farmhouse Resort & Spa
  • Support local Cambodians
Starts / Ends
Phnom Penh / Kampong Chhnang
Activities
Spa Relaxation, Village Visits
Activity Level
Relaxed
This 4-day tour starts in Phnom Penh or Battambang. Drive about 1 hour and 30 minutes from Phnom Penh or 4 hours from Battambang. Upon arrival, settle into the Smiling Gecko Farmhouse. Relax and enjoy the natural surroundings and delicious meals provided throughout your stay.
Tour Details
0
The colorful Tonle Sap village
from $6,200
EXPLORE

Mekong Explorer - Siem Reap to Phnom Penh

5 Day Itinerary aboard Aqua Mekong
  • Visit Prek Toal Core Bird Reserve
  • Meet and interact with locals
  • Attend a Buddhist blessing ceremony
Activity Level
Variable
Embark the Aqua Mekong on this 5-day voyage down the Mekong River from Siem Reap to Phnom Penh. Stop in charming floating villages, interact with the local peoples of the area, and explore the colorful markets and cultural sites which line the shores.
Cruise Details
0
Kampong Chhnang
from $3,439
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
Cruise Details
0
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