Top Mekong River Trips & Tours in October 2025

This 14-day Mekong River cruise through Cambodia and Vietnam aboard the RV Indochine travels from Siem Reap in Cambodia to Hanoi, Vietnam observing imposing monuments, examples of finest architecture, and extraordinary landscapes, like those of famous Angkor Wat. Also visit Chau Doc, Ho Chi Minh City, Kampong Tralach, Koh Chen, My Tho, Sa Dec, & Tonle Sap Lake.

Experience the colorful culture of Vietnam and Cambodia as you embark on this 4-day Mekong River Discovery Cruise and experience a richly-rewarding adventure by heading upriver in Cambodia and exploring the Tonle Sap Lake.

Discover Cambodia on this 4-day cruise aboard RV Mekong Pandaw. Combine the ancient Khmer martial art of Bokator in Silk Island with a visit to Vipassana Dhura Meditation Center in Cambodia's ancient capital, Oudongon, on this expedition across the Tonle and Mekong Rivers.

Embark on a 16-day cruise aboard the MS Amadara, exploring Hanoi, Ha Long Bay, Siem Reap, and Ho Chi Minh City. Discover ancient temples, cruise the Mekong River, visit charming villages, and experience the vibrant blend of history and modern life in Vietnam and Cambodia.

Board the Aqua Mekong in My Tho for a 5-day Mekong River cruise of Cambodia & Vietnam, including stops in Ho Chi Minh City, Phnom Penh, and Long Son Pagoda atop Sam Mountain. Travel back in time as you cruise upriver through the thriving Mekong Delta past floating villages, colonial vestiges, and gilded pagodas.

Embark on a 5-day High Water river cruise aboard the Jayavarman from Phnom Penh to Siem Reap, and explore the captivating Cambodian culture while cruising the mighty Mekong Delta. Stop over at port towns and delve into the local culture and rich history of the cities.

From Siem Reap, Cambodia to Ho Chi Minh, Vietnam, explore the Mekong River aboard Scenic Spirit on this 8-day cruise. Explore the ancient hilltop monastery of Wat Hanchey and immerse yourself in the beauty of Khmer handicrafts in Cheung Kok.

Embark the luxurious Aqua Mekong in Phnom Pehn, Cambodia on this 4-day discovery cruise along the Mekong River all the way to Ho Chi Minh City, Vietnam. You'll peruse vibrant markets and visit typical Mekong Delta villages while getting to know local cultures and ways of life, with a visit to Vinh Trang Pagoda and opportunities to bike along the way.

Explore the wonders of Vietnam and Cambodia on this 5-day Saigon and Phnom Penh Short Cruise on the RV Bassac Pandaw. Immerse yourself into the contrasting culture of Vietnam Delta and Cambodia.

Meander along the Mekong River as you cruise from Ho Chi Minh City to Siem Reap on this 10-day Vietnam & Cambodia cruise aboard Scenic Spirit. You'll enjoy an extensive lineup of included tours, large variety of land activities, visits to rural villages, historic pagodas, floating markets and a Buddhist monastery.

This one-day Vietnam tour extension includes a cruise along the Mekong River and visits to other scenic locations. Visit Ben Tre, My Long, a coconut workshop, a bee garden, a candy mill, and a farmer's house, and ride a rickshaw past coconut trees and vegetable farms.