Have questions? We're here.
Vietnam Statue

Top My Tho Trips & Tours in December 2025

Travel made your way
Talk with an expert
Build your ideal Mekong River trip. Call 1.406.541.2677
Start Planning My Trip
Discover My Tho in December 2025 on one of these 25 tours hand-selected by the travel experts at Adventure Life. Explore the best of during December 2025 as you enjoy Village Visits, Archaeological Site Visits, Local Market Visits, Urban Exploration, and Land & Sea Exploration. Prices for trips in December 2025 range from $893 to $16,950 for a vacation of 5 to 16 days. Choose any of the below 25 itineraries in December 2025 and customize it when you contact one of Adventure Life's expert My Tho trip planners.
Filter (25 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • My Tho
Royal Palace and Silver Pagoda
from $1,956
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit the Gieng Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
Cruise Details
0
Explore the floating village of Tonle Sap
from $4,650
EXPLORE

Mekong Discovery - Phnom Penh to Ho Chi Minh

4 Day Itinerary aboard Aqua Mekong
  • Walk through verdant plantations
  • Learn about local traditions
  • Visit Vinh Trang Pagoda
  • Tour Sa Dec markets
Activity Level
Variable
Embark the luxurious Aqua Mekong in Phnom Penh, Cambodia, on this 4-day discovery cruise along the Mekong River to Ho Chi Minh City, Vietnam. You'll peruse vibrant markets and visit typical Mekong Delta villages while getting to know local cultures and ways of life, with a visit to Vinh Trang Pagoda and opportunities to bike along the way.
Cruise Details
0
Traditional mat-making
from $2,124
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
  • Hear Khmer Rouge survivor story
  • Explore Gieng Island
  • Explore My An Hung Village
  • Discover water hyacinth weaving
  • Experience Tan Phong Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
Cruise Details
0
Everyday life in Vietnam
from $3,539
EBD $4000
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
Cruise Details
0
Explore the floating village of Tonle Sap
from $11,340
EXPLORE

Mekong Expedition - Phnom Penh to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
  • Walk across Kampong Prasat
  • Learn more about the local products
  • Visit the Tuol Sleng Museum
  • Discover Tan Chau
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Kayaking
Activity Level
Variable
Admire the diverse cultures and stunning natural beauty of Cambodia & Vietnam on this 8-day river cruise aboard Aqua Mekong. Hikes and bike rides complement cultural tours and market visits as you explore the cities & sites of Cai Be, Chau Doc, Ho Chi Minh City, Kampong Chhnang, Kampong Tralach, Koh Chen, and Phnom Penh.
Cruise Details
0
Kampong Chhnang
from $6,518
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Starts / Ends
Ho Chi Minh City / Hanoi
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
Cruise Details
0
Enjoy the Mekong’s tranquil waters as colorful blooms and a rustic riverside home set a relaxed, local vibe.
from $3,539
EBD $4000
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
Cruise Details
0
Phnom Penh Royal Palace complex
from $2,124
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • See Cai Be’s rice & candy making
  • Explore the Gieng Island
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Floating Market in Cai Be
from $1,956
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • See the floating market in Cai Be
  • Explore the Gieng Island
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $3,981
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine
  • Visit the Banteay Srei temple
  • Explore the terrace of Elephants
  • Discover Kampong Chhnang
  • Tour Phnom Penh's National Museum
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.
Cruise Details
0
Woman on a boat in Vietnam
from $2,296
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City - Siem Reap - 9 Day Itinerary aboard RV Indochine II
  • Join a tour of Ho Ci Minh City
  • Observe Chau Doc´s vibrant market
  • Experience a trip in a “tuk tuk”
  • See Kampong Chhnang´s fish farms
Activity Level
Variable
Discover the culture and history of Vietnam & Cambodia on this 9-day cruise from Ho Chi Minh City to Siem Reap aboard the RV Indochine II, departing from Vietnam's Ho Chi Minh City towards Cambodia's Siem Reap, with stops in My Tho & Phnom Penh along the way.
Cruise Details
0
Boat floating along the Mekong River
from $3,788
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Explore Angkor Ban village
  • Discover Phnom Penh’s heritage
  • Visit Gieng Island workshops
  • Experience My An Hung life
  • Savor local culinary traditions
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Village Visits, Archaeological Site Visits, Cooking Classes
Activity Level
Variable
Sail aboard the Jayavarman on an 8-day Mekong River cruise from Siem Reap to Saigon. Explore riverside villages, ancient temples, and vibrant delta communities while enjoying authentic Cambodian and Vietnamese culture, cuisine, and scenic river life.
Cruise Details
0
Local moving cattle through the fields
from $5,550
EXPLORE

From the Temples of Angkor to the Mekong Delta & Hanoi and Halong Bay

14 Day Itinerary aboard RV Indochine
  • Discover 3 historical cities
  • Cross through the Cho Gao canal
  • Visit 4 major temples in Angkor
  • Meet locals and learn their culture
Starts / Ends
Siem Reap / Hanoi
Activity Level
Variable
This 14-day Mekong River cruise through Cambodia and Vietnam aboard the RV Indochine travels from Siem Reap in Cambodia to Hanoi, Vietnam observing imposing monuments, examples of finest architecture, and extraordinary landscapes, like those of famous Angkor Wat. Also visit Chau Doc, Ho Chi Minh City, Kampong Tralach, Koh Chen, My Tho, Sa Dec, & Tonle Sap Lake.
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $2,726
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City to Siem Reap - 9 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cruise across Tonle Sap Lake
  • Explore Sa Dec’s Huynh Thuy Le
  • Visit Chau Doc temples
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Urban Exploration
Activity Level
Variable
Embark on a 9-day Mekong River cruise aboard RV Indochine through Vietnam and Cambodia. Begin in Ho Chi Minh City and travel to Siem Reap, exploring temples, pagodas, markets, floating villages, and cultural landmarks along the way. Enjoy guided city tours, traditional crafts, and authentic cuisine.
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $2,726
EXPLORE

From Siem Reap to the Mekong Delta

Siem Reap to Ho Chi Minh City - 9 Day Itinerary aboard RV Indochine
  • Visit Koh Chen village
  • Explore Chau Doc’s pagodas
  • Visit Cai Be workshops
  • Discover Ho Chi Minh landmarks
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Set sail on a 9-day Mekong River cruise through Cambodia and Vietnam aboard RV Indochine. Explore Siem Reap, Phnom Penh, Chau Doc, Sa Dec, Cai Be, My Tho, and Ho Chi Minh City. Visit temples, markets, pagodas, and local villages while experiencing authentic cultural traditions. Enjoy guided tours, regional flavors, and cultural performances.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $4,235
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap to Ho Chi Minh City - 11 Day Itinerary aboard RV Indochine II
  • Visit Angkor Wat temples
  • Explore Phnom Penh landmarks
  • Visit Cu Chi tunnels in Saigon
  • Discover Koh Chen crafts
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Local Market Visits, Land & Sea Exploration
Activity Level
Variable
Embark on an 11-day Mekong River cruise through Vietnam and Cambodia aboard RV Indochine II. Start in Siem Reap with Angkor temples, then sail across Tonle Sap Lake and explore Phnom Penh, Chau Doc, Sa Dec, Cai Be, and Ho Chi Minh City. Visit floating villages, historic landmarks, and cultural sites.
Cruise Details
0
Aerial view of Angkor Wat
from $3,215
EXPLORE

From the Mekong Delta to the Angkor Temples

Ho Chin Min City to Angkor - 11 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cu Chi tunnels tour
  • Explore Angkor Wat temples
  • Tour Sa Dec historic house
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Experience an 11-day Mekong River cruise from Vietnam to Cambodia aboard RV Indochine. Explore Ho Chi Minh City landmarks, My Tho canals, Phnom Penh palaces, and Siem Reap’s Angkor temples. Visit bustling markets, floating villages, craft villages, and historic sites. Discover culture, tradition, and history on a unique river adventure through Southeast Asia.
Cruise Details
0
Bike in front of Angkor Wat
from $6,370
EXPLORE

From the Mekong Delta to the Temples of Angkor & Hanoi and Halong Bay

Hanoi to Angkor Temples - 14 Day Itinerary aboard RV Indochine II
  • Explore Hanoi’s historic sites
  • Learn Cambodian history
  • Ride sampans through canals
  • Cruise scenic Halong Bay
Starts / Ends
Hanoi / Siem Reap
Activity Level
Variable
Travel from Hanoi to Siem Reap on a 14-day cruise-tour aboard RV Indochine II. Explore Vietnam’s capital, cruise Halong Bay, and visit Ho Chi Minh City. Journey along the Mekong River to discover floating villages, bustling markets, and temples.
Cruise Details
0
1-18 of 25 Results

Top Mekong River Travel Destinations

Mekong River Trips by Departure Date

Top Experiences in Mekong River

Mekong River Trips by Duration

Mekong River Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By