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The upper Mississippi region

Hannibal Missouri River Cruises

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Experience the historic charm and scenic beauty of Hannibal, Missouri with Adventure Life's array of 6 cruises for 2025. Join us on a cruise journey along the Mississippi River, where you can immerse yourself in the stories of Mark Twain, explore the quaint streets of this riverside town, and enjoy the stunning views of the surrounding bluffs. Engage in cultural experiences, food & wine tastings, and wildlife viewing opportunities, all while sailing on a relaxing river cruise. From the bustling riverfront to the serene countryside, each moment offers a unique opportunity to discover the heart of this iconic American destination. With tours ranging from 9 to 23 days, now is the perfect time to plan your adventure to Hannibal and contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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View the iconic arch when you visit St. Louis, gateway to the west
$12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Variable
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
Mississippi River, St. Paul Minnesota
$5,545
Savings
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Melody
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a cruise along the Upper Mississippi River, exploring St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's home, witness diverse landscapes, and enjoy expert-guided tours. Adapt to the river's character as you relax on lounges, decks, or …
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
$11,755
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends:
St. Paul / New Orleans
Activities:
Village Visits
Activity Level:
Variable
Embark on a 16-day cruise aboard American Serenade and begin by exploring St. Paul's art galleries and historic Summit Avenue. In La Crosse, enjoy Riverside Park and panoramic views from Grand Dad’s Bluff. Discover Dubuque, with its Victorian mansions and the Mississippi River Museum …
Cruise Details
0
The upper Mississippi region
$6,999
EXPLORE

America’s Heartland

St. Louis to St. Paul - 12 Day Itinerary aboard Viking Mississippi
  • Discover history of the Mississippi
  • Explore Dubuque, Iowa
  • Experience Mississippi river towns
  • Admire local artisan work
Starts / Ends:
St. Louis / St. Paul
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Variable
On this enlightening journey on the Upper Mississippi, hear stories of pioneers and the Lewis and Clark Expedition; walk in the footsteps of Mark Twain; and learn about the Norwegian migration. Enjoy the view as your ship navigates through the river’s intricate lock system. Experience the …
Cruise Details
0
Visit historic Minneapolis
$15,640
Savings
EXPLORE

Complete Mississippi River

New Orleans - St. Paul - 23 Day Itinerary aboard American Melody
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends:
New Orleans / St. Paul
Activity Level:
Variable
Embark on a 23-day Mississippi River cruise, spanning 10 states on the American Melody. Explore the cultural tapestry of the Mighty Mississippi, touching on history, charm, and scenic landscapes. From lively New Orleans to Minneapolis, discover Baton Rouge's history, St. Francisville's …
Cruise Details
0
Mississippi River, St. Paul Minnesota
$4,530
Savings
EXPLORE

Upper Mississippi River

St. Louis, MO to St. Paul, MN - 9 Day Itinerary aboard American Heritage
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Witness wildlife and nature
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on a cruise along the Upper Mississippi River, exploring St. Louis, Alton, Hannibal, Muscatine, Dubuque, Winona, and Red Wing. Visit Mark Twain's home, witness diverse landscapes, and enjoy expert-guided tours. Adapt to the river's character as you relax on lounges, decks, or …
Cruise Details
0
1-6 of 6 Results
TrustScore 4.8 | 404 reviews
TrustScore 4.8 of 5
total score
Based on 404 reviews on
review score
23 hours ago
Franny has been such an amazing help with all my trip planning. This is our 3rd trip to plan with her and she is always so willing to assist and find the best deals for my family and friends.
Suzanne Turbyfill
review score
3 days ago
Our advisor at Adventure Life, Mary Curry, was knowledgable and quick to respond with answers to any questions we had. She made our booking efficiently and set up a time for us to make a secure payment through her directly. We’ve used Adventure Life repeatedly and would definitely recommend it.
Sarika FREY
review score
3 days ago
Very efficient and responsive.
Patricia
review score
4 days ago
I selected Adventure Travel as I was not satisfied with the responsiveness of the agent for the cruise I was trying to book and it had good recommendations. So far, I am quite happy with my agent, Betty, very responsive and accommodating.
charles
review score
4 days ago
Jess was great. Our plans changed and we had to make some adjustments and she was super helpful. Finding us a cost-effective alternative to our original trip plan.
Glenn

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