Top South America Trips & Tours in October 2025

Experience the highlights of Chile on our favorite vacation package starting in the North and ending in the South of this impossibly long, narrow country. Explore the arid Atacama Desert, stroll Santiago's streets, and hike, bike, raft and more in the Lakes District near Puerto Varas. Finish …

Spend nine days trekking through the Patagonian landscape on this Patagonia Hiking Express tour. Explore Perito Moreno Glacier, the Fitz Roy Range, Laguna Torre, El Calafate, Torres del Paine, and more. Hike through glaciers, past massifs, to lagoons, and through glaciated mountain ranges. Enjoy …

Experience the cuisine of Argentina and Uruguay while remaining active on this adventurous 13-day vacation. Spend time in Mendoza, the wine capital of Argentina, tantalizing Buenos Aires & Montevideo, and the Uruguayan coast. Enjoy cooking classes, light hikes, wine & city tours, a tango …

From Cusco take a flight to Lima and then to the jungle town of Iquitos. This is the heart of the Amazon and the headwaters of the greatest ecological zone on earth. A motor boat takes you 25 miles downstream to the Ceiba Tops Lodge, a beautiful sanctuary with air-conditioned rooms, hot water …

From Buenos Aires head south, lace your boots, and take to the mountains to begin your Patagonia trekking adventure. Fly to El Calafate, a charming Patagonian city, then on to the small mountain town of El Chalten, where you'll spend 4 full days exploring the inspiring mountains of the …

This five day Brazil tour offers a range of activities designed to highlight the best of the archipelago. This Brazil trip can be customized to your interests and preferences with activities ranging from hiking, surfing, snorkeling, scuba diving, and wildlife viewing. Fernando de Noronha is a great …

Discover the remote and breathtaking landscape of the Aysen, Chile region on this active Patagonia tour. Previously unreached before recent construction of the Carretera Austral, this isolated Patagonia wilderness offers the outdoor enthusiast an array of options. Kayak the famous Marble Caves, …

Embark on a 4-day cruise through the Eastern Galapagos Islands aboard the Hermes Ultra Luxury Cruise. Begin at San Cristóbal Island, exploring Tijeretas and the Galapagos' history at the Interpretation Center. Dive into the archipelago's volcanic origins and conservation efforts. …

Set sail on a 4-day cruise to the North & Central Galapagos Islands aboard the Hermes Ultra Luxury Cruise. Start in Baltra, transfer to meet your guide, and explore Santa Cruz's highlands, encountering Galápagos giant tortoises and lava tunnels. On day two, visit Cerro Dragón …

Hike the classic Inca Trail while camping in style. This 4-day Inca Trail trek is combined with an upscale camping experience offering cots, hot water showers, and incredible views. Climb up to 13,800 feet, pass glacier covered peaks and descend into lush, green cloudforests. Enjoy fine cuisine …

Board the Ocean Spray for this 6 day Galapagos adventure. Visit Black Turtle Cove to view blacktip and whitetip reef sharks, Kicker Rock for exceptional snorkeling and the nesting site of the Waved Albatross on Espanola Island.

Explore the northern islands of the Galapagos on this 5 day cruise aboard the Ocean Spray. Once on board cruise to Bartolome Island and hike to the summit of the volcano for panoramic views. You also will trek through mangroves and view tidal pools teeming with sea lions and reef fish on Genovesa …

Within the majestic Vilcabamba range, the glacier-capped summit of Mount Salkantay rises grandly above the neighboring peaks. Local Quechua Indians consider Salkantay to be sacred, worshiping the mountain as their ancestors have for thousands of years. After exploring colonial Cusco and the Sacred …

Embark on an 8-day Hermes Ultra Luxury Cruise to explore the Central East & Southern Galápagos Islands. Witness giant tortoises and lava tunnels on Santa Cruz, discover Rábida's red sand beach and unique palo santo trees and encounter diverse wildlife on South Plaza and Santa …

Set sail on an 8-day, exciting trip to the Northwestern Galapagos Islands aboard the Hermes Ultra Luxury Cruise. Explore Santa Cruz's highlands, see Galápagos giant tortoises in their natural habitat, and delve into underground lava tunnels. Visit Cerro Dragón to witness land …