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Top South America Trips & Tours in May 2025

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Trekking in Patagonia
from $4,132
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Patagonia Hiking Express

9 Day Itinerary
  • Hike to the Base of the Towers
  • Premier day hikes in El Chalten
  • Ice trekking on Perito Moreno
  • Explore all that Patagonia offers
Activity Level
Challenging
Enjoy an adventurous 9-day Patagonia Express hiking and trekking trip exploring Argentina's Los Glaciares National Park, Perito Moreno Glacier, El Calafate, and Chile's Torres del Paine.
Tour Details
0
Us at La Mitad del Mundo - where water drains straight down
from $125
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Quito - Middle of the World

½ Day Itinerary
  • Explore historic Quito streets
  • Stand on the Equator
  • Discover Pululahua Crater views
Activities
Urban Exploration
Activity Level
Relaxed
Spend half a day exploring the historic city of Quito, Ecuador. Explore Quito's historic streets, the Equator line, and Pululahua Crater. Uncover hidden treasures, vibrant culture, and breathtaking views in this unforgettable Ecuadorian journey.
Tour Details
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Chile Wine Adventure
from $3,506
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Chile Wine Adventure

8 Day Itinerary
  • Explore Santiago City
  • Discover Los Dominicos
  • Bike through Colchagua Valley
  • Visit Viña del Mar and Valparaíso
Starts / Ends
Santiago / Santiago
Activities
Biking
Activity Level
Moderate
Hike, bike, taste wine, and enjoy traditional Chilean cuisine on this week-long tour through the Santiago Valley. Your journey includes a city tour of Santiago's historical sites and a tour of several local wineries. This tour can be customized to increase or decrease the activity level based on your preferences.
Tour Details
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Wildlife watching in the Amazon in traditional dugout canoes
from $915
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Ceiba Tops Amazon Lodge

4 Day Itinerary
  • Witness pink or gray dolphins
  • View wildlife from the canopy
  • Learn about Amazon holistic healing
Activities
Wilderness Lodge Exploration
Activity Level
Relaxed
Explore Peru's vast jungle with a 3-night stay at Ceiba Tops Lodge. Make your way to Iquitos, the headwaters of the Amazon, and travel down the river to your jungle home. Visit an indigenous community and view wildlife from the canopy during your stay.
Tour Details
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Cotopaxi Volcano with snow
from $168
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Cotopaxi National Park

1 Day Itinerary
Activity Level
Relaxed
Explore Cotopaxi, the earth's highest active volcano (19347ft/5897m) with possibilities of seeing the Andean Condor. This is a full-day tour including a hike to the volcano's refuge lodge and a short walk to the nearest glacier.
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Tree frog spotted in the Amazon
from $4,920
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Luxury Amazon Discovery - High Water

4 Day Itinerary aboard Aqua Nera
  • Visit the Manatee Rescue Center
  • Journey through Jungle of Mirrors
  • Discover the town of Nauta
Starts / Ends
Iquitos / Nauta
Activities
Local Market Visits, Village Visits, Fishing, Rainforest Exploration
Activity Level
Variable
Embark on this 4-day Amazon River luxury cruise on the Aqua Nera, from the Amazon port town of Iquitos. Your journey includes Yacapana Islands, Lake Clavero, Pacaya Samiria National Reserve, and the major tributaries of Ucayali and Maranon. Keep your eyes open for the mysterious pink river dolphin along the way, and enjoy activities like hiking & kayaking.
Cruise Details
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Relax in the waters of Fernando de Noronha
from $1,346
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Fernando de Noronha

5 Day Itinerary
  • Hike to spectacular beaches
  • Snorkel and swim in Atlantic waters
  • Learn about conservation efforts
Activities
Scuba Diving
Activity Level
Relaxed
Fernando de Noronha, an archipelago located off of Brazil's northwest coast, epitomizes the term 'island paradise.' Home to some of the world's most pristine, picturesque beaches, Fernando de Noronha is the perfect destination for travelers seeking an authentic Brazilian experience in a tropical setting unparalleled in beauty.
Tour Details
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Guanaco in Torres del Paine
from $2,850
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Explora Torres Del Paine

5 Day Itinerary
  • Hike through Patagonia
  • Search for Patagonian wildlife
  • Choose your excursions
Starts / Ends
Explora Torres del Paine / Torres del Paine National Park
Activities
Horseback Riding, Wine Tasting, Spa Relaxation
Activity Level
Easy Active
Explora Torres del Paine is in the middle of the Torres del Paine National Park. It offers beautiful views of the Lake Pehoe and 49 rooms. Explora also has its own spa, ranch, and stables for your enjoyment and you can choose from a variety of excursions to create your optimal itinerary.
Tour Details
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See giant tortoises in the Galapagos
from $8,016
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Wildlife Odyssey

Amazon & Galapagos - 15 Day Itinerary
  • Observe macaws at a clay lick
  • Visit a 130-ft. observation tower
  • Take in the vast array of wildlife
  • Snorkel through clear waters
Activities
Hacienda Visits
Activity Level
Relaxed
Discover three natural wonders of the world in one amazing trip: the Galapagos Islands, the Amazon Rainforest, and the Andes Mountains of Ecuador. Starting in Quito, fly to Sacha Lodge, deep in the Amazon, followed by the indigenous markets of Otavalo, staying at historic Hacienda Pinsaqui, culminating in the Wildlife Odyssey on an 8-day Galapagos cruise.
Tour Details
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sally lightfoot crab
from $4,050
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Southern Islands

5 Day Itinerary aboard Treasure of Galapagos
Starts / Ends
San Cristobal Airport / Baltra
Activity Level
Variable
This 5-day Southern Galapagos Islands cruise on the Treasure of the Galapagos yacht explores the islands of Santa Cruz, San Cristobal, Santa Fe and more.
Cruise Details
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Camping along the Inca Trail
from $8,079
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Luxury Inca Trail

10 Day Itinerary
Activity Level
Challenging
Hike the Inca Trail in style and comfort. This 10-day Inca Trail trek & exploration of Andean Peru is combined with an upscale camping experience offering comfortable cots, hot water showers, and fine cuisine served under a portable dining tent. Top-shelf service and highly knowledgeable guides assure your once-in-a-lifetime trip to Machu Picchu is perfect.
Tour Details
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Sea lion in the Galapagos
from $6,195
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Southern Islands

San Cristobal - Baltra - 4 Day Itinerary aboard Hermes Ultra Luxury Cruise
  • Visit Tijeretas Hill bird colony
  • Discover Floreana Island's beaches
  • Snorkel with sea lions
Starts / Ends
San Cristobal Airport / Baltra
Activity Level
Variable
Set sail on a 4-day Hermes Ultra Luxury Cruise to the Eastern Galapagos Islands. Explore San Cristóbal, and visit Tijeretas Hill. Enjoy Gardner Bay and Punta Suárez on Española, then discover unique beaches, flamingos, and marine life at Punta Cormorant on Floreana. Conclude your journey at the Charles Darwin Research Station and fly back home.
Cruise Details
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Brilliantly colored flamingos
from $6,195
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Northern Islands

Baltra roundtrip - 4 Day Itinerary aboard Hermes Ultra Luxury Cruise
  • Spot giant tortoises in Highlands
  • Visit Cerro Dragón and see iguanas
  • Explore Genovesa Island's paradise
Starts / Ends
Baltra / Baltra
Activities
Hiking, Wildlife Viewing, Snorkeling, Kayaking, Stand Up Paddle Boarding
Activity Level
Variable
Embark on a 4-day North & Central Islands cruise aboard the Hermes Ultra Luxury Cruise. Observe Santa Cruz Highlands' giant tortoises and lava tunnels. Journey to Dragon Hill, home to land iguanas and flamingos then visit Chinese Hat. Explore El Barranco cliffs and Darwin Bay's bird paradise. Conclude with a marine life excursion in Black Turtle Cove.
Cruise Details
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Our guide as the sun breaks through the clouds
from $3,316
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Inca Pathways

Inca Trail - 13 Day Itinerary
  • Explore floating islands
  • Visit the highlights of Cusco
  • Tour pre-Colombian salt mines
  • Trek the Inca Trail to Machu Picchu
Activities
Archaeological Site Visits, Camping, Homestays
Activity Level
Challenging
This two-week trek explores the ancient and revered pathway known as the Inca Trail through the Sacred Valley of the Inca. Spend 4 days hiking the 26-mile Inca Trail, culminating in Machu Picchu at the Sun Gate. This tour also spends time before the trek acclimating and exploring Lake Titicaca and Cusco.
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South Plaza Island
from $8,195
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Central East Islands

Baltra - San Cristobal - 5 Day Itinerary aboard Hermes Ultra Luxury Cruise
  • Explore the Santa Cruz highlands
  • Hike to Bartolomé's summit
  • Land at South Plaza for forest walk
  • Greet playful sea lions
Starts / Ends
Baltra / San Cristobal Airport
Activity Level
Variable
Set sail on a 5-day cruise from Baltra to San Cristobal aboard Hermes Ultra Luxury Cruise in the Central East Galapagos Islands. Explore Santa Cruz's highlands and lava tunnels, Rábida's red sand beach, Bartolomé's volcanic panoramas, and South Plaza's land iguanas. Discover more flora and fauna while enjoying up-close wildlife encounters.
Cruise Details
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Flamingos
from $6,190
NO SS
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Luxurious Southern Galapagos Cruise

6 Day Itinerary aboard Ocean Spray
  • Visit the Waved Albatross colony
  • Snorkel with sharks at Kicker Rock
  • Leave a letter at Post Office Bay
  • Hike the cliffs at Pitt Point
Starts / Ends
Baltra / Baltra
Activity Level
Variable
On this 6-day luxury Galapagos cruise aboard one of the best yachts in Galapagos, the Ocean Spray catamaran, you'll see giant Galapagos tortoises, playful sea lion colonies, marine iguanas, blue-footed boobies, and if traveling the right time of year, waved albatrosses on Espanola Island.
Cruise Details
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Snorkeling near the Yucatan Peninsula, Mexico
from $5,190
NO SS
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Northern Galapagos Catamaran Cruise

5 Day Itinerary aboard Ocean Spray
  • Hike 375 stairs to panoramic views
  • Trek through mangroves
  • Snorkel in search of marinlife
Starts / Ends
Baltra / Baltra
Activity Level
Variable
The Ocean Spray luxury catamaran takes you on a 5-day Galapagos Northern Islands cruise, exploring Genovesa, South Plaza, Mosquero, and Santiago. Light hiking, pristine snorkeling, and swimming with sea lions and penguins make this trip the perfect luxury Galapagos vacation package.
Cruise Details
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Mt Veronica - It is a beautiful mountain!
from $4,177
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Salkantay & Classic Inca Trail Trek

12 Day Itinerary
Starts / Ends
Lima / Lima
Activity Level
Challenging
This 12-day trek takes you along the legendary route of the Inca Trail, through the Sacred Valley and exploring the traditional colonial town of Cusco - hiking through mountain passes, glacier carved valleys, and ultimately leading to the renowned Sun Gate of Machu Picchu.
Tour Details
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