Top South America Trips & Tours in May 2025

This 7-day tour of Ecuador's Avenue of the Volcano explores the history and culture of the Andes while staying in luxurious haciendas: Hacienda Rumiloma overlooking Quito, traditional Hacienda Zuleta near Otavalo, and the former Inca palace of San Agustin de Callo in the shadows of fuming Cotopaxi Volcano.

Our mainstay Machu Picchu trip with luxury accommodations. We visit the most important Inca ruins such as Sacsayhuamán, Pisac, and Ollantaytambo, and we spend two days exploring the Lost City of Machu Picchu. This is an easy paced weeklong journey perfect for anyone with a sense of curiosity and adventure.

This 16-day tour highlights the best of Peru, including Islas Ballestas and Paracas, the Nazca Lines, Colca Canyon, the islands of Lake Titicaca, Cusco and the Lost City of the Incas--Machu Picchu. From the coast to the Andes to the Amazon jungle, this tour has a little bit of everything!

The land of the Incas near Cusco and the Sacred Valley is a great destination for active adventures. With deep canyons cut by beautiful rivers and backroads and trails in the shadows of the impressive Andes, explore the countryside during this multi-day biking and raft trip and visit the Inca cities of Cusco and Ollantaytambo. Travelers will have a half-day hike on a remote section of the Inca Trail to hike down to the Apurimac River, one of South America's premier rivers. Single-track and more advanced biking routes can be arranged based on travelers' experience.

Begin and end your nine-day trip discovering the best of Ecuador high in the Andes where we'll explore the colonial capital city of Quito. Then, bargain with colorfully-dressed indigenous women in the Otavalo Market, visit the Bellavista Cloud Forest, Cotopaxi Volcano & National Park and the town of Baños on this tour of the best of the Ecuadorian Andes.

This 8-day multisport adventure to the Galapagos Islands is packed with thrilling and unique experiences. Begin your action-packed trip with a trek on San Cristobal Island, and then continue with kayaking, snorkeling, and biking around the Galapagos, where wildlife awaits at every turn, trailside, and shoreline!

Explore Chiclayo and the Tucume Pyramids and Sipan ruins before continuing into the cloudforest to the lost civilization of Chachapoyas. This trip in northern Peru features visits to the huge mountaintop temple and fortress of Kuelap, the Leimebamba museum with its collection of 200 mummies, and the Revash tombs. There is an optional hike to Gocta Falls, the world's third tallest free-falling waterfall.

Torres del Paine National Park offers a combination of unique wildlife and spectacular scenery in one of the most isolated regions of South America. Travel through Punta Arenas, Chile, or El Calafate, Argentina to arrive at EcoCamp. After full days of exploring the park return and rest in comfort in the new Suite Domes!

Combine 8 days in the Galapagos with a trip to Peru and Machu Picchu. Explore Cusco, and the Sacred Valley, and spend two days discovering Machu Picchu learning about the ancient ways of the Incas and the traditions of Andean people today. Then fly to the Galapagos Islands for 8 days of wildlife & natural discovery!

Bike down the slopes of Pichincha Volcano, hike through dense, biodiverse cloud forest, zip-line over the forest canopy, hike, and ride horses through the high Andes near the active 19,347-foot high Cotopaxi Volcano on this exciting 9-day adventure tour of Ecuador.

Enjoy a complete 10-day upscale tour discovering the best of Argentina. Dance the tango in Buenos Aires, float down the Tigre Delta, take a cooking class and go wine tasting in Mendoza. Explore the peaks and lakes of the high Andes hiking at a historical Estancia near Bariloche in Patagonia.

Begin this week-long Argentina vacation in metropolitan Buenos Aires before traveling to Iguazu Falls, the world's largest waterfall system at the Argentine-Brazilian border. Enjoy the best Argentina has to offer with visits to local fruit markets at the Tigre Delta, ferry tours, tango shows and of course, Argentine steak & wine.

Immerse yourself in the mystical culture, epic landscapes, and ocean views of legendary Easter Island. Visit the mysterious Moai statues, walk and drive around the island’s best natural and archeological sites, and learn more about this fascinating island!

La Perla hosts this 4-day Amazon cruise from Iquitos. Explore the Amazon, Ucayali, and Pacaya Rivers on their way deep into the Pacaya Samiria Reserve. Trek into the dense jungle in search of Amazon wildlife and birds, take a night safari and guided trips, visit local villages, and learn about wildlife preservation efforts in Peru’s Amazonia.

Spend two weeks exploring the undiscovered northern regions of Brazil on this active & remote vacation that shows you the authentic side of the Brazilian lifestyle. This tour combines trekking through the sand dunes of Lencois Maranhenses National Park, the beach sports mecca of Jericoacoara, and the isolated tropical paradise Fernando de Noronha.

Explore the south-eastern islands of San Cristobal, Española, Floreana, and Santa Cruz on this unforgettable 5-day cruise aboard the 100-guest Galapagos Legend small cruise ship.

On this fascinating 5-day trip to the highlands of Ecuador, you'll begin your tour in charming colonial Cuenca, then travel to the Ingapirca ruins and the Tomebamba River, Riobamba, Cotopaxi National Park, and the thrilling Nariz del Diablo train ride before returning to Quito.

Indulge in the unique beauty of the Galapagos Islands on this 7-day adventure aboard M/Y Monserrat. Learn about the history of this unique archipelago, rest on a white sand beach, view abundant wildlife, and take advantage of once-in-a-lifetime snorkel opportunities.