Top South America Trips & Tours in April 2025

Spend nine days trekking through the Patagonian landscape on this Patagonia Hiking Express tour. Explore Perito Moreno Glacier, the Fitz Roy Range, Laguna Torre, El Calafate, Torres del Paine, and more. Hike through glaciers, past massifs, to lagoons, and through glaciated mountain ranges. Enjoy …

Experience the cuisine of Argentina and Uruguay while remaining active on this adventurous 13-day vacation. Spend time in Mendoza, the wine capital of Argentina, tantalizing Buenos Aires & Montevideo, and the Uruguayan coast. Enjoy cooking classes, light hikes, wine & city tours, a tango …

From Cusco take a flight to Lima and then to the jungle town of Iquitos. This is the heart of the Amazon and the headwaters of the greatest ecological zone on earth. A motor boat takes you 25 miles downstream to the Ceiba Tops Lodge, a beautiful sanctuary with air-conditioned rooms, hot water …

Join the Aqua Nera in the remote colonial city of Iquitos, Peru for this 4-day luxury Amazon River Cruise. Journey along the Ucayali River, the Amazon’s largest tributary, as well as other neighboring rivers (the Yarapa and Dorado), each one rich in vibrant wildlife and thriving rainforests. …

From Buenos Aires head south, lace your boots, and take to the mountains to begin your Patagonia trekking adventure. Fly to El Calafate, a charming Patagonian city, then on to the small mountain town of El Chalten, where you'll spend 4 full days exploring the inspiring mountains of the …

This five day Brazil tour offers a range of activities designed to highlight the best of the archipelago. This Brazil trip can be customized to your interests and preferences with activities ranging from hiking, surfing, snorkeling, scuba diving, and wildlife viewing. Fernando de Noronha is a great …

Explora Torres del Paine, located in the middle of Torres del Paine National Park, is a luxurious home base for your explorations of the park. Each day you'll be able to choose from a variety of excursions to create your optimal itinerary. With on-site stables and expert guides, hiking and …

Discover the remote and breathtaking landscape of the Aysen, Chile region on this active Patagonia tour. Previously unreached before recent construction of the Carretera Austral, this isolated Patagonia wilderness offers the outdoor enthusiast an array of options. Kayak the famous Marble Caves, …

Explore the highlights of Uruguay during this 13-day self-drive tour. Begin the journey in the romantic city of Colonia del Sacramento, explore the charming cobblestone streets and learn about the Portuguese and Spanish influence. Drive northwest along the coast where will spend two days in the …

Embark on a 4-day cruise through the Eastern Galapagos Islands aboard the Hermes Ultra Luxury Cruise. Begin at San Cristóbal Island, exploring Tijeretas and the Galapagos' history at the Interpretation Center. Dive into the archipelago's volcanic origins and conservation efforts. …

Set sail on a 4-day cruise to the North & Central Galapagos Islands aboard the Hermes Ultra Luxury Cruise. Start in Baltra, transfer to meet your guide, and explore Santa Cruz's highlands, encountering Galápagos giant tortoises and lava tunnels. On day two, visit Cerro Dragón …

Hike the classic Inca Trail while camping in style. This 4-day Inca Trail trek is combined with an upscale camping experience offering cots, hot water showers, and incredible views. Climb up to 13,800 feet, pass glacier covered peaks and descend into lush, green cloudforests. Enjoy fine cuisine …

Board the Ocean Spray for this 6 day Galapagos adventure. Visit Black Turtle Cove to view blacktip and whitetip reef sharks, Kicker Rock for exceptional snorkeling and the nesting site of the Waved Albatross on Espanola Island.

Explore the northern islands of the Galapagos on this 5 day cruise aboard the Ocean Spray. Once on board cruise to Bartolome Island and hike to the summit of the volcano for panoramic views. You also will trek through mangroves and view tidal pools teeming with sea lions and reef fish on Genovesa …

Spend five days in the heart of Patagonia National Park, with guanacos roaming the grounds, walks just outside your door, and the opportunity to observe this massive rewilding project firsthand. With their superb guides, first-rate meals, and excellent service, Explora enables you to discover this …

Within the majestic Vilcabamba range, the glacier-capped summit of Mount Salkantay rises grandly above the neighboring peaks. Local Quechua Indians consider Salkantay to be sacred, worshiping the mountain as their ancestors have for thousands of years. After exploring colonial Cusco and the Sacred …