Top South America Trips & Tours in April 2025

Take in the sights, sounds, food, and culture as you explore Santiago, Buenos Aires, and Rio de Janeiro. This 10 day itinerary includes free days and optional activities so you can set the pace of your South American vacation!

Spend 5 days touring the western vineyards of Uruguay while exploring Colonia del Sacramento with its rich cultural heritage and the charming area of Carmelo. Visit multiple wineries and taste their own varieties of wine.

Adventure Life's guides and partners has identified the poorest families in the Cachiccata community. The elements can cause damage to homes over time, and many families do not have the extra means to make renovations to their homes. During this 4 day/3 night trip, participants, side-by-side with the family members, will work on cleaning, repairing, and restoring their homes. We stay in the community campground each night to immerse ourselves in the village life. The trip ends with traditional Inca ceremony and offering as a time to reflect over the previous days' experiences.

This week-long river cruise onboard La Perla is ideal for flora and fauna enthusiasts who want to experience the Amazon rainforest. This region of the world is a birding enthusiast's paradise. Also, witness pink river dolphins in a way you've never seen them before.

Take the opportunity to meet Argentina’s capital city, Buenos Aires! Often referred to as one of South America’s (and maybe the world’s) most exciting cities, Buenos Aires offers fabulous food, world famous wine, the Tango, amazing art, interesting neighborhoods. The city is interesting by day, and captivating by night.

Visit a traditional Estancia founded at the end of the 19th century just outside Torres del Paine National Park. Meet your local Baqueano (Patagonian cowboy) guide, who introduces you to the fine selection of Patagonian horses. Cross the Baguales River, famous for fly fishing due to its calm waters and lively trout.

Experience a 2 day/1 night whitewater rafting trip on the Urubamba River, the sacred river of the Incas. Raft through Class II-IV rapids on this trip that includes one overnight of camping and great food after your day's adrenaline-filled adventure on this great river.

This 2-day extension features an overnight in Copacabana. You will explore Lake Titicaca, at the crossroads of the Andes and the Andean plateau and the world's highest navigable lake. Immerse yourself in the legend that the son of Inti, the sun god, emerged as the first Inca from the waters of Lake Titicaca.

Set sail towards the Sapote River, a protected area of the Pacaya-Samiria National Reserve, on a 5-day Amazon cruise on the Zafiro. As translators for indigenous people, naturalist guides utilize their eagle eyes to help you spot and learn about Amazonian species.

Travel from Argentina to Brazil to see Iguazu Falls from two perspectives. View the falls from below in Argentina and then get a panoramic view over the falls from the Brazil side.

Embark on this 8-day Amazon River Expedition Cruise aboard Aqua Nera where you will experience the most luxurious and comprehensive Amazon journey among the Amazon River’s two powerful tributaries: the Marañon and the Ucayali, as well as several hidden black water lakes.

This 8-day cruise offers incredible snorkeling, hiking, and kayaking adventures all around the Galapagos archipelago in style. Gourmet cuisine, the best guides, and spacious & stylish cabins guarantee a top-notch luxury cruising experience second to none.

Explore Peru's vast jungle with a 3-night stay at Sandoval Lake Lodge. Set amidst a rich biologically diverse haven, Sandoval allows visitors to rise early for otter watching, view Brown Capuchin Monkeys, spot Black Caimans or catch a glimpse of Red-Bellied Macaws. Nature hikes and motor canoeing allow you to get up close to the incredible wildlife.

Join the Zafiro on this 8-day journey showcasing the mighty Amazon River’s treasures. Navigate deep into Pacaya Samiria Reserve for a real and safe adventure to spot the wonderful creatures of the Amazon!

An 8-day river cruise on the awe-inspiring Amazon awaits you aboard the Aria Amazon. Get up and personal with wildlife like Amazon dolphins and monkeys, interact with local indigenous people, eat fantastic food, and learn from naturalist guides while exploring Pacaya-Samiria Reserve in the company of just 32 passengers.

This 5-day itinerary on the Manatee is designed to highlight the incredible biodiversity, wildlife, and natural beauty found in the Amazon.

Savor the flavors of Peru on a 4-day gastronomy tour through Lima, a UNESCO World Heritage city. Indulge in Peruvian delicacies at renowned restaurants