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Patagonia Fly + Cruise Adventures

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Cruise Patagonia on one of these 7 hand-picked flight and cruise combination trips by Adventure Life. Many consider combining a flight with a cruise where you normally fly one way and cruise the opposite way as the best way to see Patagonia as they let you cover more distance in less time. Some of the most popular things to do on a fly-cruise adventure to Patagonia are Kayaking, Whale Watching, Wildlife Viewing, Adventure Options, and Snorkeling. Prices for cruises to Patagonia in 2025 start at $4,995 to $38,495 for voyages of 6 to 12 days. Tell us about your ideal Patagonia experience and one of Adventure Life's travel specialists can help you design the perfect, seamless trip.
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from $12,995
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Magellan Discoverer Inaugural Air-Cruise

Roundtrip Punta Arenas - 10 Day Itinerary aboard Magellan Discoverer
  • Start your adventure in Punta Arena
  • Enjoy Patagonia Adventures
  • Beagle Channel and Drake Passage
  • Antarctic Exploration
  • Return Flight from King George Isla
Starts / Ends
Punta Arenas / Punta Arenas
Activities
Wildlife Viewing, Whale Watching
Activity Level
Variable
Embark on a 10-day cruise on the Magellan Discoverer from Punta Arenas to Antarctica. Sail the Strait of Magellan, explore Glacier Alley, and cross the Drake Passage to the South Shetland Islands and Antarctic Peninsula. Spend three days discovering fjords, icebergs, and wildlife before flying back from King George Island.
Cruise Details
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from $6,795
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Antarctica Express Air Cruise

Punta Arenas - Ushuaia - 6 Day Itinerary aboard Magellan Discoverer
  • Visit the South Shetland Islands
  • Drake Passage navigation
  • Explore Puerto Williams
  • Chance to visit Cape Horn
Starts / Ends
Punta Arenas / Port of Ushuaia
Activity Level
Variable
The Antarctica Express Air cruise is a compact 6-day expedition. Begin in Punta Arenas, Chile, with a flight to King George Island to explore penguin colonies, ice-filled bays, and Antarctic wildlife. Sail through the Drake Passage, spot seabirds and whales, and, weather permitting, land at Cape Horn. Conclude in Ushuaia, Argentina.
Cruise Details
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from $17,895
25% OFF
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Antarctic Explorer - Fly/Sail Expedition

Ushuaia - Punta Arenas - 12 Day Itinerary aboard Sylvia Earle
  • See the activity of a penguin city
  • Chance to spot leopard seals
  • Cruise on a Zodiac
Starts / Ends
Punta Arenas / Ushuaia
Activities
Scuba Diving
Activity Level
Variable
Explore Antarctica on this 12-day cruise from Ushuaia to Punta Arenas aboard Sylvia Earle. Reduce your time at sea by flying one way over the Drake Passage and sailing the other way. Discover the Antarctic Peninsula, South Shetland Islands, and the Legendary Cape Horn.
Cruise Details
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Two Glacier Mountains symmetrically reflecting in the Antarctic water
from $18,695
25% OFF
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Antarctica: Through the Lens - Fly/Sail Expedition

12 Day Itinerary aboard Greg Mortimer
  • Fly over the Drake Passage
  • Spot penguins, seals, and whales
  • Take Zodiac cruises
  • Photograph glaciers and icebergs
Starts / Ends
Punta Arenas / Ushuaia
Activities
Snorkeling, Adventure Options, Kayaking
Activity Level
Variable
Embark on the 12-day Antarctic Explorer - Fly/Sail Expedition from Punta Arenas to Ushuaia aboard the Greg Mortimer. Fly over the Drake Passage to maximize your time exploring the Antarctic Peninsula. Experience vast glaciers, penguins, seals, and whales. Take Zodiac cruises, photograph icebergs, and witness skuas.
Cruise Details
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Albatross nest amid rolling hills in Falkland Islands
from $20,395
25% OFF
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Antarctic Explorer - Fly/Sail Expedition

Punta Arenas - Ushuaia - 12 Day Itinerary aboard Douglas Mawson
  • Join a Fly/Sail cruise expedition
  • Spot Antarctic wildlife
  • Witness Antarctic Peninsula glacier
  • Watch whales in Antarctic waters
Starts / Ends
Punta Arenas / Ushuaia
Activity Level
Variable
Embark on the 12-day Antarctic Explorer - Fly/Sail Expedition from Punta Arenas to Ushuaia aboard the Douglas Mawson. Fly over the Drake Passage to maximize your time exploring the Antarctic Peninsula. Experience vast glaciers, penguins, seals, and whales. Take Zodiac cruises, photograph icebergs, and witness skuas.
Cruise Details
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Air transportation
from $5,995
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Antarctica Express Air Cruise

Ushuaia - Punta Arenas - 6 Day Itinerary aboard Magellan Explorer
  • Visit the legendary Cape Horn
  • Attend presentations and lectures
  • Sail through ice-filled bays
  • Explore Antarctic bases & stations
Starts / Ends
Port of Ushuaia / Punta Arenas
Activity Level
Variable
The shortest possible trip to Antarctica is this 6-day cruise/flight starting in Ushuaia, through the Beagle Channel, legendary Cape Horn, and mythical waters of the Drake Passage to experience a day in one of the most spectacular places on earth - Antarctica! Return on a flight from King George Island to Patagonia's Punta Arenas, Chile.
Cruise Details
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Incredible ice formations
from $4,995
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Antarctica Express Air Cruise

6 Day Itinerary aboard Ocean Nova
  • Visit the legendary Cape Horn
  • Attend presentations and lectures
  • Sail through ice-filled bays
  • Explore Antarctic bases & stations
Starts / Ends
Port of Ushuaia / Punta Arenas
Activity Level
Variable
The fastest possible trip to Antarctica, and one of most economical is this 6-day cruise/flight starting in Ushuaia. Sail the Beagle Channel, Cape Horn, and mythical Drake Passage to experience a day in one of the most spectacular places on earth - Antarctica! Return on a flight from King George Island to Patagonia's Punta Arenas, Chile.
Cruise Details
0
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