Check in at  409 San Martín Ave in downtown Ushuaia between 10:00 and 17:00 (10 AM-5 PM) on the day of your cruise departure. Board the M/V Ventus Australis at 18:00 (6 PM). After a welcoming toast and introduction of captain and crew, the ship departs for one of the most remote corners of planet Earth. During the night traverse the Beagle Channel and cross from Argentina into Chilean territorial waters. The lights of Ushuaia disappear as you turn into the narrow Murray Channel between Navarino and Hoste Islands.

Around the break of dawn, Ventus Australis crosses Nassau Bay and enters the remote archipelago that comprises Cape Horn National Park. Weather and sea conditions permitting, go ashore on the windswept island that harbors legendary Cape Horn (Cabo de Hornos). Discovered in 1616 by a Dutch maritime expedition, and named after the town of Hoorn in West Friesland, Cape Horn is a sheer 425-meter- (1,394-foot) high rocky promontory overlooking the turbulent waters of the Drake Passage. For many years it was the only navigation route between the Pacific and Atlantic, and was often referred to as the "End of the Earth." The park was declared a World Biosphere Reserve by UNESCO in 2005. The Chilean navy maintains a permanent lighthouse on the island, staffed by a lightkeeper and his family, as well as the tiny Stella Maris Chapel and modern Cape Horn Monument.

Sailing back across Nassau Bay, anchor at fabled Wulaia Bay, one of the few places in the archipelago where the human history is just as compelling as the natural environment. Originally the site of one of the region’s largest Yámana aboriginal settlements, the bay was described by Charles Darwin and sketched by Captain FitzRoy in the 1830s during their voyages on HMS Beagle. This area is also renowned for its mesmerizing beauty and dramatic geography. After a visit to the Australis-sponsored museum in the old radio station, which is especially strong on the Yámana people and European missionaries in the area, passengers have a choice of three hikes (of increasing degrees of difficulty) that ascend the heavily wooded mountain behind the bay. On all of these you stroll through an enchanted Magellanic forest of lengas, coigües, canelos, and ferns to reach panoramic viewpoints overlooking the bay.

Overnight, continue your Patagonia glacier tour around the western end of Tierra del Fuego via the very narrow Gabrial Channel, Magdalena Channel, and Cockburn Channel. After rounding the remote Brecknock Peninsula, the ship tacks eastward and enters the Beagle Channel again. By morning arrive at Pia Fjord and board the Zodiacs for a shore excursion to Pia Glacier. After disembarking take a short hike to gain a panoramic view of the spectacular glacier, which extends from the mountaintops down to the sea or a longer much more difficult walk up a lateral moraine of the old Pia Glacier.

No one knows for certain how the hulking mass of snow and ice got its feminine moniker, but one theory says it was named for Princess Maria Pia of Savoy (1847-1911), daughter of the Italian king.

Making your way further west along the Beagle Channel, enter another long fjord and drop anchor near Garibaldi Glacier for another shore excursion. Garibaldi is one of only three glaciers in Patagonia gaining mass rather than staying the same or slowly shrinking. This time hike through virgin Magellanic forest to a glacial waterfall, a towering wall of ferns and moss, and spectacular viewpoints looking down on the glacier and fjord. The walk is demanding, with very steep, negligible trail and rough footing, and is not for everyone. For those who choose to stay onboard, the captain points the bow towards the beautiful sky-blue Garibaldi Glacier so everyone can enjoy the panoramic view from the upper decks.

Early in the morning, sail through the Cockburn Channel and enter Agostini Sound. From there it is possible to see the glaciers that descend from the middle of the Darwin Mountain Range, some of them reaching the water. This morning, disembark and go for an easy walk around a lagoon, which was formed by the melting of the Águila Glacier. Reach a spot right in front of that glacier with stunning views. In the afternoon, approach the Condor Glacier via Zodiac, and hopefully see some of the abundant Andean condors in the area.

After an overnight cruise through Magdalena Channel and back into the Strait of Magellan, anchor off Magdalena Island, which lies about halfway between Tierra del Fuego and the Chilean mainland. Crowned by a distinctive lighthouse, the island used to be an essential source of supplies for navigators and explorers and is inhabited by an immense colony of Magellanic penguins. At the break of dawn, weather permitting, go ashore and hike a path that leads through thousands of penguins to a small museum lodged inside the vintage 1902 lighthouse. Many other bird species are also found on the island. In September and April, when the penguins dwell elsewhere, this excursion is replaced by a ride aboard Zodiacs to Marta Island to observe South American sea lions. After a short cruise south along the strait, disembarkation at Punta Arenas is scheduled for around 12:30 PM.

*Camera extension poles are prohibited on Magdalena Island.