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Top Palermo Tours & Cruises in 2025

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Trevi Fountain in Rome
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Balate Dorin
Visit charming Sicily
Lipari
Roman Babakin
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Discover Palermo in 2025 on one of these trips hand selected by the travel experts at Adventure Life. Select any of the below 8 top-rated trips where you will explore Palermo, Valletta, Trapani, Syracuse, and Cagliari with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Palermo in are archaeological site visits, small ship cruises, cruises, luxury, and village visits. Our Palermo trips in 2025 range in price from $3,000 to $33,800 for trips of 8 to 12 days. Contact one of Adventure Life's expert Palermo trip planners for help planning a seamless experience.
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    • Palermo
Visit charming Sicily
$3,000
Savings
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Treasures of Sicily

Italy Small Group Tour - 9 Day Itinerary
  • Visit the Island of Sicily
  • Discover the Valley of the Temples
  • Visit Taormina's ancient ruins
  • See the Mount Etna in Sicily
  • Explore the coastal town of Cefalu
  • Visit Syracuse's Archeological Park
  • Discover the Zingaro Nature Reserve
Starts / Ends:
Viagrande / Taormina
Activities:
Archaeological Site Visits, Hiking, Village Visits, Wine Tasting
Activity Level:
Relaxed
Explore the Treasures of Sicily on this 9-day small group tour from Viagrande to Taormina, a collection of extraordinary wonders found on the beautiful Italian island of Sicily. Sicily is home to well-preserved Greek temples showcasing the island's ancient past. The Valley of the Temples in …
Tour Details
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Sunset over Palermo
$3,799
Savings
EXPLORE

Sicilian Sunsets & Amalfi Delights

Malta - Naples - 8 Day Itinerary aboard Variety Voyager
  • Explore Port Empedocle
  • Discover Trapani
  • Explore Sorrento
  • Explore Palermo
Starts / Ends:
Valletta / Naples
Activities:
Archaeological Site Visits, Small Ship Cruises, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise aboard the Variety Voyager from Malta's charming capital, Valletta, through Sicily and Southern Italy. Visit Agrigento's UNESCO-listed Temple Valley, explore the medieval streets of Erice, and delve into Palermo's Mafia history while savoring Sicilian cuisine. …
Cruise Details
0
Explore historic Bonifacio atop the cliffs of Corsica
$7,690
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Valletta - Nice - 8 Day Itinerary aboard Le Bougainville
  • Discover Mediterranean islands
  • Experience ancient ruins
  • Admire Byzantine-Arab mosaics
  • Explore medieval towns
  • Discover local cuisine
Starts / Ends:
Valletta / Nice
Activities:
Archaeological Site Visits, Land & Sea Exploration, Small Ship Cruises, Village Visits
Activity Level:
Variable
Embark on this 8-day Mediterranean Island Voyage with Smithsonian Journeys from Valletta to Nice on Le Bougainville where you can engage in discussions with two Smithsonian Journeys Experts onboard. Explore five Mediterranean islands on one itinerary, starting from Malta and moving on to Sicily, …
Cruise Details
0
Tour the charming city of Valletta, Malta.
$8,370
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valletta - Valletta - 9 Day Itinerary aboard Le Bougainville
  • Take a loop around Sicily
  • Discover Sicily's beautiful cities
  • Visit Syracuse
  • Explore Palermo
Starts / Ends:
Valletta / Valletta
Activities:
Archaeological Site Visits, Small Ship Cruises
Activity Level:
Variable
Cruise around Sicily aboard the new luxury expedition ship Le Bougainville, while exploring mythical places at the crossroads of Eastern and Western civilizations. Discover Sicily's most beautiful historic cities and ancient sites. Valletta, the capital of Malta, is the departure point. Then, …
Cruise Details
0
Relax in beautiful Sicily
$8,490
EXPLORE

Longing for La Dolce Vita

Sicily - Italy - 8 Day Itinerary aboard Sea Cloud Spirit
  • Visit Taormina
  • Discover Palermo
  • Explore Lipari
  • Explore Amalfi
Starts / Ends:
Catania / Naples
Activities:
Small Ship Cruises, Small Ship Sailing
Activity Level:
Variable
Join an 8-day "Longing for La Dolce Vita" cruise from Sicily to Italy aboard the Sea Cloud Spirit. The adventure begins in Taormina, a town set high on cliffs, known for its blend of cultures and varied cuisine. Explore Palermo, where you can visit the historic palazzi and see the gold …
Cruise Details
0
Explore ruins in Sicily
$6,000
EXPLORE

Cruising the Mediterranean: Sicily, Sardinia, and Mallorca – with Smithsonian Journeys

Valletta - Tarragona - 8 Day Itinerary aboard L'Austral
  • Visit UNESCO charm in Valletta
  • Explore Tarragona's Roman ruins
  • Indulge in Sicilian seafood
  • Stroll Mahon's colorful streets
Starts / Ends:
Valletta / Tarragona
Activities:
Archaeological Site Visits, Local Market Visits
Activity Level:
Variable
Set sail on an unforgettable 8-day Mediterranean journey aboard L'Austral. Begin your cruise in Valletta, a UNESCO World Heritage site known for its majestic streets and historic landmarks. From the Grandmaster's palace to Saint John’s cathedral, immerse yourself in the rich history …
Cruise Details
0
Admire sun-soaked Malaga
$6,280
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From Iberian Shores to Greek Coastlines

Malaga - Athens - 11 Day Itinerary aboard Le Dumont-d'Urville
  • Explore ancient Cartagena's history
  • Discover Cagliari's architecture
  • Visit picturesque Katakolon village
  • Cross the historic Corinth Canal
Starts / Ends:
Malaga / Athens
Activities:
Archaeological Site Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Embark on an 11-day cruise from Malaga to Athens aboard Le Dumont-d'Urville, exploring Spain's rich history and diverse cultures, the Balearic Islands, Sardinia, Sicily, and Greece. From the cultural treasures of Malaga and the ancient ruins of Cartagena to the captivating beauty of Palma …
Cruise Details
0
$9,540
EXPLORE

Culture and Islands of the Mediterranean

Barcelona - Valletta - 12 Day Itinerary aboard L'Austral
  • Visit Menorca
  • Explore Sardinia
  • Discover Sicily
  • Experience Catania
  • Discover Syracuse
  • Discover Malta
Starts / Ends:
Barcelona / Valletta
Activities:
Archaeological Site Visits, Small Ship Cruises, Urban Exploration, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on a 12-day cruise from Barcelona to the Maltese coast aboard L’Austral, in partnership with Relais & Châteaux. This journey offers a blend of culinary and cultural experiences, with an included excursion per person at each port of call. Highlights include Menorca's rich …
Cruise Details
0
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