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Stop in Avignon on your cruise of the Rhône river.

Top Avignon Trips & Tours in September 2025

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Discover Avignon in September 2025 on one of these 11 tours hand-selected by the travel experts at Adventure Life. Explore the best of Avignon, Lyon, Arles, Tournon, and Viviers during September 2025 as you enjoy cruises, river cruises, biking, wine tasting, and luxury. Prices for trips in September 2025 range from $1,250 to $26,890 for a vacation of 7 to 14 days. Choose any of the below 11 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert Avignon trip planners.
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    • Avignon
Warm lights glow through the blue hour in Lyon
$3,699
Savings
EXPLORE

Colors of Provence - Cruise Only

Lyon - Arles - 8 Day Itinerary aboard MS Amakristina
  • Tour the highlights of Lyon, France
  • Stop at the home of a local vintner
  • Learn about olive farming tradition
  • Take the Artist Experience tour
Starts / Ends:
Lyon / Arles
Activities:
Biking, Cooking Classes, Hiking, River Cruises, Wine Tasting
Activity Level:
Variable
Cruise through France's famed wine regions, including Beaujolais and the Côte du Rhône. Your 8-day European river cruise adventure begins in Lyon, France. Visit local wineries for wine tastings, marvel at old Roman ruins, meander through medieval villages, and shop for Provencal …
Cruise Details
0
Stop in Avignon on your cruise of the Rhône river.
$2,799
EXPLORE

Lyon & Provence

Avignon - Lyon - 8 Day Itinerary aboard Viking River Cruises
  • Explore Avignon
  • Experience Arles' vibrant city
  • Visit Viviers’ Old Town
  • Discover Beaujolais
Starts / Ends:
Avignon / Lyon
Activities:
Small Ship Cruises
Activity Level:
Variable
Tap into your inner van Gogh at an Arles painting class. Discover Roman Provence at Les Arènes amphitheater and the Pont du Gard. Explore Avignon’s Palace of the Popes. Excite your palate in Lyon, capital of French gastronomy. Savor Beaujolais wines. Hunt for truffles and see how …
Cruise Details
0
Cruise the Rhone river in charming Lyon
$1,250
EXPLORE

The tip of Provence to Lyon on the Rhone and Saone River

7 Day Itinerary aboard MS Rhone Princess
  • Discover the Vercors Massif
  • The Camargue and its customs
  • Visit Avignon's Papal Palace
  • Explore Beaujolais
Starts / Ends:
Martigues / Macon
Activities:
Local Market Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Discover Provence, one of France's most beautiful, magnificent, and fascinating regions, on this seven-day river cruise onboard the MS Rhone Princess. Nature and ancient traditions have been carefully conserved in Avignon. Next, travel on to Lyon and its strategic doorways. Head to the wine …
Cruise Details
0
Famous view of Lyon, France
$13,690
2-for-1
EXPLORE

Spectacular South of France

11 Day Itinerary aboard Scenic Sapphire
  • Tour St. Rémy & St. Paul de Mausole
  • Enjoy a concert at Palais des Papes
  • Explore Château de Cormatin
  • Explore Lyon
Starts / Ends:
Lyon / Lyon
Activities:
Cooking Classes, Small Ship Cruises, Urban Exploration, Village Visits
Activity Level:
Variable
Embark on this 11-day cruise through Lyon. Visit the estate of Château Meursault and taste some of its acclaimed wines, join a guided walk of Tain l’Hermitage or enjoy a hike to Heritage Hill. Take a tour of the city of Avignon to explore the Popes’ Palace and the famed St. …
Cruise Details
0
Sprawling vineyards of France
$6,349
EXPLORE

Colors of Provence

14 Day Itinerary aboard MS Amakristina
  • Enjoy Lyon's culinary delights
  • Visit the Beaujolais wine region
  • Join a Provencal cooking lesson
  • Admire Antoni Gaudi’s works
Starts / Ends:
Paris / Barcelona
Activities:
Archaeological Site Visits, Biking, Cooking Classes, River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Cruise through France’s legendary wine growing regions, home to such famous vintages as Beaujolais and Côte du Rhône. Enjoy wine tastings at local vintners, marvel at ancient Roman ruins, stroll through medieval villages, and shop for Provencal crafts. Visit the UNESCO World …
Cruise Details
0
Discover the history and art of Barcelona
$5,229
EXPLORE

Essence of Burgundy & Provence

14 Day Itinerary aboard MS Amacello
  • Visit Chillon Castle
  • Cooking class in Valence
  • Explore Tournus
  • Enjoy the “City of Gaudi” Barcelona
Starts / Ends:
Chalon Sur Saone / Barcelona
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
From romantic cities to foodie havens and artistic epicenters, this 14-day itinerary enlivens all your senses. Spend three nights in Geneva before going to Lyon, France’s culinary capital. Savor the beauty of legendary vineyards and imbibe in local vintages like Beaujolais and Côtes du …
Cruise Details
0
Stop in Avignon on your cruise of the Rhône river.
$3,799
EXPLORE

Burgundy & Provence

Arles - Lyon - 8 Day Itinerary aboard S.S. Catherine
  • Enjoy a visit to ruins in Tarascon
  • Tour the Rue de Doux old city
  • Learn about silk weaving at Lyon
Starts / Ends:
Arles / Lyon
Activities:
Archaeological Site Visits, Biking, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on an unforgettable cruise aboard the S.S. Catherine for 8 days, journey through Burgundy & Provence. Immerse yourself in the region's rich culture as you savor its renowned wine and cuisine. Wander through the historic streets of Arles, made famous by Van Gogh himself. Marvel at the …
Cruise Details
0
Cruise the Rhone river in charming Lyon
$4,609
Savings
EXPLORE

Active & Discovery on the Rhone

Southbound - 8 Day Itinerary aboard Avalon Poetry II
  • Explore Lyon’s hidden passageways
  • Discover Tournon’s medieval city
  • Taste chocolate in Tain-l’Hermitage
  • Visit Avignon’s iconic Palace
Starts / Ends:
Lyon / Arles
Activities:
Biking, Hiking, Kayaking, River Cruises, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise aboard the Avalon Poetry II. Explore lavender fields, fine wines, and inspiring vistas, and set the stage for a vacation filled with choice and adventure. Bike alongside rivers while bird-watching, kayak through majestic gorges, or savor wine in incredible cave depths. …
Cruise Details
0
Arles overview
$7,590
2-for-1
EXPLORE

Sensations of Lyon and Provence

Lyon - Marseille - 8 Day Itinerary aboard Emerald Liberté
  • Explore Lyon
  • Discover Chalon-sur-Saône
  • Experience Tournon
  • Uncover the rich history of Arles
Starts / Ends:
Lyon / Marseille
Activities:
Biking, Hiking, River Cruises, Village Visits
Activity Level:
Variable
Embark on an 8-day cruise from Lyon to Marseille on the Emerald Liberté. The South of France's reputation as photography's birthplace is well known, boasting exceptional French 15th-century architecture, Roman remnants, and vineyards bathed in sunlight nestled against imposing …
Cruise Details
0
Stop in Avignon on your cruise of the Rhône river.
$3,799
EXPLORE

Colors of Provence - Cruise Only

Arles - Lyon - 8 Day Itinerary aboard MS Amakristina
  • Tour the highlights of Lyon, France
  • Stop at the home of a local vintner
  • Learn about olive farming tradition
  • Take the Artist Experience tour
Starts / Ends:
Arles / Lyon
Activities:
Biking, Cooking Classes, Hiking, River Cruises, Wine Tasting
Activity Level:
Variable
Cruise through France's famed wine regions, including Beaujolais and the Côte du Rhône. Your 8-day European river cruise adventure begins in Arles, France, the city where Vincent Van Gogh spent most of his life. Visit local wineries for wine tastings, marvel at old Roman ruins, …
Cruise Details
0
The architectures of Lyon
$3,699
EXPLORE

Essence of Burgundy & Provence - Cruise Only

8 Day Itinerary aboard MS Amacello
  • Visit Chillon Castle
  • Cooking class in Valence
  • Explore Tournus
  • Enjoy the “City of Gaudi” Barcelona
Starts / Ends:
Chalon Sur Saone / Barcelona
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
Indulge in French flavors on a palate-pleasing 8-day river cruise that highlights the essence of France’s Burgundy and Provence. Uncover the Roman history of Chalon-sur Saône and delight in charming Tournus with its towering Romanesque abbey and historic apothecary shop. Visit French …
Cruise Details
0
1-11 of 11 Results
TrustScore 4.8 | 405 reviews
TrustScore 4.8 of 5
total score
Based on 405 reviews on
review score
2 days ago
Wonderful personal attention to detail and very helpful suggestions by experienced travel experts
John K
review score
3 days ago
Franny has been such an amazing help with all my trip planning. This is our 3rd trip to plan with her and she is always so willing to assist and find the best deals for my family and friends.
Suzanne Turbyfill
review score
6 days ago
Our advisor at Adventure Life, Mary Curry, was knowledgable and quick to respond with answers to any questions we had. She made our booking efficiently and set up a time for us to make a secure payment through her directly. We’ve used Adventure Life repeatedly and would definitely recommend it.
Sarika FREY
review score
6 days ago
Very efficient and responsive.
Patricia
review score
1 week ago
I selected Adventure Travel as I was not satisfied with the responsiveness of the agent for the cruise I was trying to book and it had good recommendations. So far, I am quite happy with my agent, Betty, very responsive and accommodating.
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