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Top Mekong River Trips & Tours in September 2025

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Discover Mekong River in September 2025 on one of these 25 tours hand-selected by the travel experts at Adventure Life. Explore the best of Phnom Penh, Kampong Chhnang, Ho Chi Minh City, Siem Reap, and My Tho during September 2025 as you enjoy river cruises, cruises, village visits, local market visits, and luxury. Prices for trips in September 2025 range from $1,250 to $12,600 for a vacation of 5 to 16 days. Choose any of the below 25 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
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    • Mekong River
The beautiful Vinh Trang temple near My Tho
$2,741
EXPLORE

Mekong River - Upstream - High water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Phnom Penh cultural sites
Starts / Ends:
Ho Chi Minh City / Siem Reap
Activities:
Archaeological Site Visits, Cooking Classes, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Embark on an 8-day river cruise aboard The Jahan, an elegant British-Indian colonial-style riverboat, and explore the Mekong River during the high water season, from Saigon to Siem Reap. Immerse yourself in the rich heritage and diverse cultures of the Mekong Delta as you visit charming rural …
Cruise Details
0
Flower farms in Sa Dec, Vietnam
$2,529
EXPLORE

Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Explore rural villages
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Explore floating markets
  • Discover cultures of Mekong Delta
Starts / Ends:
Ho Chi Minh City / Siem Reap
Activities:
Archaeological Site Visits, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Embark on this 8-day high-water river cruise aboard the Jayavarman traveling from Saigon to Siem Reap along the Mekong River. Immerse in the diverse heritage and cultures of the Mekong Delta by visiting rural villages, historical pagodas, and vibrant markets. Get a chance to interact with the …
Cruise Details
0
Phnom Penh Royal Palace complex
$1,243
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Starts / Ends:
Ho Chi Minh City / Phnom Penh
Activities:
Archaeological Site Visits, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Join this 4-day Lower Mekong river cruise from Saigon to Phnom Penh aboard the luxurious British-Indian colonial-style riverboat, The Jahan. During your trip, learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets. Engage with locals and witness …
Cruise Details
0
Sunset over the Mekong River
$2,529
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Starts / Ends:
Siem Reap / Ho Chi Minh City
Activities:
Archaeological Site Visits, Cooking Classes, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Join this 8-day high-water cruise aboard the Jayavarman. Cruise from Siem Reap to Saigon to experience the best of the Mekong River, exploring the scenic landscapes and exciting port cities along the way. During your trip, learn about the culture and heritage with visits to rural villages, historic …
Cruise Details
0
Phnom Penh Royal Palace complex
$1,231
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Starts / Ends:
Ho Chi Minh City / Phnom Penh
Activities:
Archaeological Site Visits, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Join this 4-day Lower Mekong river cruise from Saigon to Phnom Penh aboard the luxurious French-Colonial-style riverboat, the Jayavarman. During your trip, learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets. Engage with locals and witness …
Cruise Details
0
Floating Market in Cai Be
$2,741
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Starts / Ends:
Siem Reap / Ho Chi Minh City
Activities:
Archaeological Site Visits, Cooking Classes, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Join this 8-day high-water Mekong river cruise aboard the Jahan. Cruise from Siem Reap to Saigon to experience the best of the Mekong River, exploring the scenic landscapes and exciting port cities along the way. During your trip, learn about the culture and heritage with visits to rural villages, …
Cruise Details
0
Royal Palace and Silver Pagoda
$1,231
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Starts / Ends:
Phnom Penh / Ho Chi Minh City
Activities:
Archaeological Site Visits, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
On this 4-day river cruise aboard the Jayavarman from Phnom Penh to Saigon, discover Cambodia and Vietnam's diverse cultures. During your trip, learn about the culture and heritage of the Lower Mekong River with visits to rural villages, historic pagodas, and colorful markets. Engage with …
Cruise Details
0
Floating village in Southeast Asia
$1,532
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Starts / Ends:
Siem Reap / Phnom Penh
Activities:
Archaeological Site Visits, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Cruise the mighty Mekong River from Siem Reap to Phnom Penh on this 5-day High Water river cruise and discover the diverse culture of Cambodia. Discover the pre-Angkorian temples, rural communities, and breathtaking Tonle Riverine landscapes as you travel across the Mekong Delta. Take a motorized …
Cruise Details
0
Traditional mat-making
$1,243
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
  • Experience Binh Thanh Island
  • Explore My An Hung Village
  • Discover Tan Chau
  • Experience Cao Dai
Starts / Ends:
Phnom Penh / My Tho
Activities:
Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Embark on a 4-day river cruise aboard the Jahan. From Phnom Penh to Tan Chau, immerse yourself in a world of cultural wonders and natural beauty. As you sail towards Vietnam, indulge in massages, culinary workshops, and afternoon tea. Explore Tan Chau's vibrant town life, visit a fish farm, and …
Cruise Details
0
Royal Palace and Silver Pagoda
$1,505
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Starts / Ends:
Siem Reap / Phnom Penh
Activities:
Archaeological Site Visits, Local Market Visits, Small Ship Cruises, Village Visits
Activity Level:
Variable
Cruise the mighty Mekong river from Siem Reap to Phnom Penh aboard the Jahan on this 5-day high water river cruise and discover the diverse culture of Cambodia. Discover the pre-Angkorian temples, rural communities, and breathtaking Tonle Riverine landscapes as you travel across the Mekong Delta. …
Cruise Details
0
Everyday life in Vietnam
$2,599
EXPLORE

Charms of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
  • Visit candy & rice paper workshops
  • Take a traditional “xe-loi” ride
  • Explore Phnom Penh´s colored market
  • Attend a Buddhist Blessing Ceremony
Starts / Ends:
Ho Chi Minh City / Siem Reap
Activities:
Local Market Visits, River Cruises, Village Visits
Activity Level:
Variable
Lively Ho Chi Minh City, once known as the “Peal of the Orient,” offers a vibrant mix of old and new and provides the perfect start to your incredible journey through Vietnam and Cambodia. Cruise along the mighty Mekong, discovering a glimpse into another era; one where people still …
Cruise Details
0
The colorful Tonle Sap village
$10,290
Savings
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap (Extension)

Low water - 8 Day Itinerary aboard Aqua Mekong
  • Discover My An Hung
  • Enjoy a traditional performance
  • Learn to cook Mekong dishes
  • Visit Cambodia's National Museum
  • Past by Buddhist temples
Activities:
Biking, Local Market Visits, River Cruises, Small Ship Cruises, Village Visits
Activity Level:
Variable
Experience the full history of Mekong life, meeting Khmer farmers, Buddhist monks and our entrepreneurial friends in Vietnam’s kaleidoscopic wet markets along the way. Travel by skiff along Bassac Canal to Chau Doc floating market then head off by van to Long Son Pagoda atop Sam Mountain. Ask …
Cruise Details
0
Kampong Chhnang
$5,378
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
  • Explore Ho Chi Minh
  • Discover the Cai Be floating market
  • Admire the Evergreen island
  • Visit a Buddhist monastery
  • Enjoy a Apsara Dancing Show
Activities:
Hiking, Land & Sea Exploration, Local Market Visits, River Cruises, Village Visits
Activity Level:
Variable
Embark your exotic Mekong cruise in My Tho Port, outside of Ho Chi Minh City. Visit rural villages, historic pagodas, floating markets, and a Buddhist monastery along the way. Overnight in Phnom Phen, capital of Cambodia. Spend a night on a contemporary junk with traditional accents. Conclude your …
Cruise Details
0
The beautiful Angkor Wat
$10,290
Savings
EXPLORE

Mekong Expedition - Siem Reap to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
  • Visit Prek Toal Core Bird Reserve
  • Sail to floating village Chhnok Tru
  • See Cambodia's capital & sights
  • Meet & interact with locals
Activities:
Biking, Local Market Visits, River Cruises, Village Visits, Wildlife Viewing
Activity Level:
Variable
Join the Aqua Mekong on an eight-day Mekong River river cruise. Take in all the mysteries and wonders that have been unearthed between the Mekong and Tonle Sap rivers and amid the varied cultures. Along the trip, learn about Mekong life's complete history and meet Khmer farmers, Buddhist monks, …
Cruise Details
0
Explore the floating village of Tonle Sap
$10,290
Savings
EXPLORE

Mekong Expedition - Phnom Penh to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
  • Walk across Kampong Prasat
  • Learn more about the local products
  • Visit the Tuol Sleng Museum
  • Discover Tan Chau
Starts / Ends:
Phnom Penh / Ho Chi Minh City
Activities:
Biking, Local Market Visits, River Cruises, Small Ship Cruises
Activity Level:
Variable
Discover all the mysteries and wonders we have discovered between the Mekong and Tonle Sap River and among the diverse cultures thriving in our midst. Celebrate the onward journey towards the heart of this mighty river with a Khmer apsara performance, an indigenous tradition memorialized on the …
Cruise Details
0
Working in the fields
$2,499
EXPLORE

Vietnam, Cambodia, and the Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
  • Ride an oxcart through rice paddies
  • Explore famous sites of Phnom Pehn
  • Tour former military base Xeo Quyt
  • Discover Evergreen Island
Activities:
Archaeological Site Visits, Land & Sea Exploration, Local Market Visits, River Cruises, Village Visits
Activity Level:
Variable
Cruise the Tonle Sap River from Siem Reap to Ho Chi Minh. Visit local villages for the opportunity to take an oxcart ride through rice paddies, tour a silk factory, and peruse colorful markets. Enjoy an overnight in Phnom Pehn and experience vibrant nightlight. End this 8-day cruise in Ho Chi Minh …
Cruise Details
0
Vietnam's bird sanctuary
$10,290
Savings
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong
  • Experience vibrant markets
  • Enjoy touring Cambodia's capital
  • Visit Long Son Pagoda
  • Explore Prek Toal Core Bird Reserve
Starts / Ends:
Ho Chi Minh City / Siem Reap
Activities:
Biking, Cooking Classes, Local Market Visits, River Cruises, Spa Relaxation, Village Visits, Wildlife Viewing
Activity Level:
Variable
Join the Aqua Mekong on this 8-day luxury Mekong River expedition cruise and discover all the mysteries and wonders between the Mekong and Tonle Sap Rivers. Enjoy the diverse cultures thriving in your midst. Experience the full history of Mekong life, meeting Khmer farmers, Buddhist monks, and …
Cruise Details
0
The colorful Tonle Sap village
$6,080
EXPLORE

Mekong Explorer - Siem Reap to Phnom Penh

5 Day Itinerary aboard Aqua Mekong
  • Visit Prek Toal Core Bird Reserve
  • Meet and interact with locals
  • Attend a Buddhist blessing ceremony
Activities:
Biking, Local Market Visits, River Cruises, Village Visits, Wildlife Viewing
Activity Level:
Variable
Delve deeper into the captivating landscape on this 5-day Mekong River explorer cruise. Concentrating solely on Cambodia’s timeless pastoral serenity, travel back in time as you sail downriver from Siem Reap to Phnom Penh. Stop in charming floating villages and interact with the local peoples …
Cruise Details
0
1-18 of 25 Results
TrustScore 4.8 | 368 reviews
TrustScore 4.8 of 5
total score
Based on 368 reviews on
review score
3 days ago
We went to the Patagonia on the Chile side and Perito Moreno in El Calafate, Argentina. Eric of San Diego handled our trip with expertise. The preparation went smoothly, despite some changes on our part with scheduling conflicts. He offered great advice which made us feel at ease with all decisions on the trip. It was truly a great experience.
Evelyn and Edwin
review score
4 days ago
We had a great experience- they were very helpful in trip planning and making sure we got to do all the activities and see the places we wanted. There were some things we couldn't do/see due to the time of year being the rainy/low season and they steered us away from those. We had never been to Costa Rica before and it gave us a good overview of this lovely country.
Jody Dice
review score
5 days ago
My travel consultant went out of her way to make sure everything went smoothly, everything from the flight reservations to the final booking.
johnw
review score
1 week ago
Angie was patient and very pleasant
Elizabeth Traxler
review score
1 week ago
Efficient and thorough.
IRWIN G

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