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Top Spain Trips & Tours in May 2025

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Discover Spain in May 2025 on one of these 22 tours hand-selected by the travel experts at Adventure Life. Explore the best of Pinhão, Porto, Regua, Vega de Terron, and Salamanca during May 2025 as you enjoy cruises, wine tasting, river cruises, food & wine, and archaeological site visits. Prices for trips in May 2025 range from $1,530 to $28,690 for a vacation of 7 to 16 days. Choose any of the below 22 itineraries in May 2025 and customize it when you contact one of Adventure Life's expert Spain trip planners.
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Porto Cityscape, Portugal
$3,699
EXPLORE

Flavors of Portugal & Spain - Cruise Only

8 Day Itinerary aboard MS Amavida
  • Explore Porto's historic old town
  • Taste Portugal's wines
  • Visit Nossa Senhora dos Remédios
  • Hike through Vega Terron, Spain
Activities:
Hiking, Small Ship Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your adventure in the city of Porto and learn more about its rich history while visiting sites such as Palacio de Mateus, located in the beautiful region of Trás-os-Montes near the city of Vila Real. The interior of the house features various religious images and exquisite furniture, …
Cruise Details
0
Salamanca, Spain
$3,699
Savings
EXPLORE

Enticing Douro

Roundtrip Porto - 8 Day Itinerary aboard MS Amadouro
  • Tour the São Bento Railway Station
  • Sample Bôlas de Lamego
  • Visit Salamanca
  • Visit the Palacio de Mateus
Starts / Ends:
Porto / Porto
Activities:
Hiking, Land & Sea Exploration, Wine Tasting
Activity Level:
Variable
Visit Porto, the beautiful “City of Bridges,”; and Salamanca, the “Golden City,” on this 8-day Douro River cruise on MS Amadouro. Taste wines from historic wineries and soak up the genuine beauty of one of Europe’s most unadulterated landscapes. Rambling vineyards and …
Cruise Details
0
Porto with Dom Luis Bridge
$4,689
EXPLORE

Enticing Douro

11 Day Itinerary aboard MS Amadouro
  • Tour Belem Tower
  • Explore the Castelo da Pena
  • Travel to Lamego
  • Enjoy Sandeman Winery
Starts / Ends:
Lisbon / Regua
Activities:
Hiking, Land & Sea Exploration, River Cruises, Wine Tasting
Activity Level:
Variable
Rambling vineyards and charming native farms cling to the steep sides of the Douro River Valley, creating an incomparable backdrop to one of Europe’s most unspoiled regions and to Port country — the world’s oldest demarcated wine region. Visit Porto, the beautiful “City of …
Cruise Details
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Explore historic Porto
$10,190
EXPLORE

Delightful Douro

Porto Roundtrip - 8 Day Itinerary aboard Scenic Azure
  • Explore the Douro Museum in Regua
  • Enjoy the elegant town of Lamego
  • Visit Salamanca
  • Be amazed by the Côa Valley Museum
Starts / Ends:
Porto / Porto
Activities:
Local Market Visits, River Cruises, Village Visits
Activity Level:
Variable
From windswept seaside meanderings to the astonishing beauty of the Douro Valley, this is a journey of contemplation and elegance. In Porto, board the luxurious Scenic Azure, which will transport through the hidden gems of the Douro Valley. Days will be spent immersed in the proud history and …
Cruise Details
0
Admire sun-soaked Malaga
$1,880
EXPLORE

Grand Prix Trials

7 Day Itinerary aboard Royal Clipper
  • Explore Malaga
  • Discover Granada
  • Experience Ibiza
  • Visit Mahon
Starts / Ends:
Malaga / Cannes
Activities:
Small Ship Cruises, Small Ship Sailing
Activity Level:
Variable
Embark on a 7-day cruise aboard the Royal Clipper through the stunning destinations of Malaga, Ibiza, Mahon, Fontvieille, and Cannes. In Malaga, marvel at the magnificent Moorish architecture of the Alcazaba and Castillo de Gibralfaro. Granada awaits with the breathtaking Alhambra Palace, a …
Cruise Details
0
Porto Cityscape, Portugal
$5,499
EXPLORE

Douro River Valley

Roundtrip Porto - 8 Day Itinerary aboard S.S. Sao Gabriel
  • Wander Salamanca's ancient streets
  • Tour Braga's rich history
  • Visit Douro Museum
  • Tour Porto’s Ribeira
Starts / Ends:
Porto / Porto
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise to and from Porto aboard the S.S. Sao Gabriel. Along the Douro River, cruising past Portugal's terraced hills, charming villages, and vineyards. Enjoy exclusive Port tastings, explore Porto's historic Ribeira district, and visit the UNESCO-listed Douro Valley. …
Cruise Details
0
Sprawling vineyards of France
$6,349
EXPLORE

Colors of Provence

14 Day Itinerary aboard MS Amakristina
  • Enjoy Lyon's culinary delights
  • Visit the Beaujolais wine region
  • Join a Provencal cooking lesson
  • Admire Antoni Gaudi’s works
Starts / Ends:
Paris / Barcelona
Activities:
Archaeological Site Visits, Biking, Cooking Classes, River Cruises, Urban Exploration, Wine Tasting
Activity Level:
Variable
Cruise through France’s legendary wine growing regions, home to such famous vintages as Beaujolais and Côte du Rhône. Enjoy wine tastings at local vintners, marvel at ancient Roman ruins, stroll through medieval villages, and shop for Provencal crafts. Visit the UNESCO World …
Cruise Details
0
Discover the history and art of Barcelona
$5,229
EXPLORE

Essence of Burgundy & Provence

14 Day Itinerary aboard MS Amacello
  • Visit Chillon Castle
  • Cooking class in Valence
  • Explore Tournus
  • Enjoy the “City of Gaudi” Barcelona
Starts / Ends:
Chalon Sur Saone / Barcelona
Activities:
River Cruises, Urban Exploration
Activity Level:
Variable
From romantic cities to foodie havens and artistic epicenters, this 14-day itinerary enlivens all your senses. Spend three nights in Geneva before going to Lyon, France’s culinary capital. Savor the beauty of legendary vineyards and imbibe in local vintages like Beaujolais and Côtes du …
Cruise Details
0
Waterways of Libourne
$6,504
EXPLORE

Taste of Bordeaux

15 Day Itinerary aboard MS Amadolce
  • Visit the Atrium
  • Tour Arcachon
  • Explore the Castle of Roquetaillade
  • Enjoy wine tasting
Activities:
Land & Sea Exploration, Wine Tasting
Activity Level:
Variable
Board the Amadolce and enjoy 2 nights in Bilbao and 2 nights in San Sebastian leading up to a 7-night roundtrip Bordeaux cruise, followed by 2 nights in the Loire Valley and 1 night in Paris. On your roundtrip Bordeaux cruise enjoy one of the world’s undisputed wine regions. Iconic …
Cruise Details
0
Visit the historic Belem tower near Lisbon
$9,015
EXPLORE

Secrets of the Douro & Lisbon

Porto - Lisbon - 11 Day Itinerary aboard Emerald Radiance
  • Visit Ruins of Lisbon
  • Experience Roman times.
  • Explore Douro Valley
  • Amaze with eclecticmix architecture
Starts / Ends:
Pinhão / Lisbon
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your journey in the Portuguese capital of Lisbon, where the cobbled alleyways and ancient ruins are yours to explore before meeting your Emerald Waterways Star-Ship in Porto. A symbol of Portugal’s birth and growth as a nation, the Douro has long been the country’s lifeline. …
Cruise Details
0
Porto with Dom Luis Bridge
$4,199
EXPLORE

Portugal's River of Gold

Lisbon-Porto - 10 Day Itinerary aboard Viking Cruises
  • Tour the Jerónimos Monastery
  • Visit Vila Real's Mateus Palace
  • Explore Castelo Rodrigo
  • Enjoy Salamanca, Spain
Starts / Ends:
Lisbon / Salamanca
Activities:
Archaeological Site Visits, River Cruises, Small Ship Cruises, Wine Tasting
Activity Level:
Variable
Take in the natural beauty and rich history of the Douro River. Experience Lisbon's renaissance, revitalized by trendy galleries and eateries. Explore two of Iberia's most historic university towns: Coimbra, Portugal, and Salamanca, Spain. Tour Porto's port warehouses and enjoy …
Cruise Details
0
Ruins Athina Pronaia temple in Ancient Delphi
$15,696
EXPLORE

Mediterranean Wonders: Sicily, Greece, Sardinia, and Beyond

Spain - Greece - 13 Day Itinerary aboard National Geographic Orion
  • Cruise the Mediterranean Sea
  • Explore standing stones on Menorca
  • Taste Sicilian wine
  • Swim at Kefalonia
  • Explore Delphi and Corinth Canal
Starts / Ends:
Barcelona / Athens
Activities:
Small Ship Cruises
Activity Level:
Variable
On this 13-day Mediterranean Wonders: Sicily, Greece, Sardinia, and Beyond Cruise from Spain to Greece aboard National Geographic Orion, traverse the Mediterranean Sea to explore ancient ruins, medieval towns, and culinary delights from Spain and Sardinia to Corsica and Greece. Walk among …
Cruise Details
0
Explore the ancient ruins of Rome
$5,999
EXPLORE

Italy & France Allure

Rome - Barcelona - 8 Day Itinerary aboard World Navigator
  • Visit the Coliseum to catacombs
  • Explore town of San Remo
  • Explore French Riviera in Menton
  • Discover food market in Barcelona
Starts / Ends:
Civitavecchia / Barcelona
Activities:
Archaeological Site Visits, Cooking Classes, Local Market Visits, Village Visits, Wine Tasting
Activity Level:
Variable
Embark on an 8-day Mediterranean voyage aboard World Navigator commencing from Civitavecchia, Italy. Begin by delving into Rome's rich history to picturesque Portofino, Livorno's gateway to Pisa and Florence, and San Remo, famed for its music festival and floral beauty. Explore Menton's …
Cruise Details
0
Visit the town of Pinhao, in the heart of the beautiful Douro Valley
$2,635
EXPLORE

From Portugal to Spain: Porto, the Douro Valley (Portugal) and Salamanca (Spain)

8 Day Itinerary aboard MS Infante Don Henrique
  • Explore Porto
  • Discover Salamanca
  • Experience Vega de Terron
  • Discover Douro Valley
Activities:
River Cruises, Wine Tasting
Activity Level:
Variable
Embark on an 8-day cruise to and from Porto aboard the MS Infante Don Henrique. Cruise through the stunning Douro Valley, filled with breathtaking scenery, historic sites, and unique experiences. Start your journey in the vibrant city of Porto, then travel through Regua to explore the region's …
Cruise Details
0
Visit the historic Belem tower near Lisbon
$9,015
EXPLORE

Lisbon & Secrets of the Douro

Lisbon - Porto - 11 Day Itinerary aboard Emerald Radiance
  • Visit Ruins of Lisbon
  • Experience Roman times.
  • Explore Douro Valley
  • Amaze with eclecticmix architecture
Starts / Ends:
Lisbon / Porto Antigo
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your journey in the Portuguese capital of Lisbon, where the cobbled alleyways and ancient ruins are yours to explore before meeting your Emerald Waterways Star-Ship in Porto. A symbol of Portugal’s birth and growth as a nation, the Douro has long been the country’s lifeline. …
Cruise Details
0
Porto with Dom Luis Bridge
$1,530
EXPLORE

Portugal to Spain - Porto, the Douro Valley and Salamanca

8 Day Itinerary aboard MS Vasco de Gama
  • Admire the city of Porto at night
  • Tour Vila Real by coach
  • Explore the old city of Salamanca
  • Visit Lamego's monumental sanctuary
Activities:
River Cruises, Wine Tasting
Activity Level:
Variable
Be carried away by the charm of the Mediterranean countries. From Portugal to Spain, you will visit Porto, a lively and fascinating city where you can taste its famous wine, or Guimarães, the beating heart of Portugal with a remarkable history that gives it today all its charm. Be guided …
Cruise Details
0
Explore beautiful Barcelona
$12,799
EXPLORE

Timeless Tastes & Treasure

Barcelona - Venice - 15 Day Itinerary aboard World Navigator
  • Visit Barrakka Panoramic Lifts
  • Explore French Riviera and Old Nice
  • Visit the town of Côte d'Azur
  • Do truffle-hunting in Tuscany
Starts / Ends:
Barcelona / Venice
Activities:
Archaeological Site Visits, Local Market Visits, Urban Exploration, Wine Tasting
Activity Level:
Variable
Embark on a 15-day Timeless Tastes & Treasure Cruise from Barcelona to Venice aboard World Navigator. Along Valletta's Grand Harbor, start with the Barrakka Panoramic Lifts, for a sunset with an extended evening in port. Enjoy a late night in Monte Carlo, to explore the scenery of the …
Cruise Details
0
Porto, Portugal Old Town
$8,290
EXPLORE

Secrets of the Douro

Porto - Porto - 8 Day Itinerary aboard Emerald Radiance
  • Visit Quinta do Tedo vineyard
  • Experience Roman times
  • Explore Douro Valley
  • Admire eclectic mix architecture
Starts / Ends:
Lisbon / Porto Antigo
Activities:
Archaeological Site Visits, River Cruises, Village Visits, Wine Tasting
Activity Level:
Variable
Start your voyage in Porto by boarding the Emerald Waterways Star-Ship. The Douro, a symbol of Portugal's origin and growth as a nation, has long served as the country's lifeblood. After leaving the pastel-colored city of Porto, travel across the enchanting countryside. The riverbanks are …
Cruise Details
0
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