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Prague City and the Charles Bridge at Sunset

Treasures of the Main & Rhine

Example 11 Day Cruise aboard MS Amadante
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Delight yourself with a luxurious river voyage from Prague to Amsterdam, aboard the MS Amadante. Spend your first 3 nights in Prague and embark upon your ship in historic Nuremberg, then cruise through the Main-Danube Canal to Bamberg. Navigate the beautiful Rhine Gorge, a UNESCO World Heritage Site, stopping along the way to visit charming Rüdesheim and Koblenz. In Cologne, visit the city’s magnificent Cathedral before concluding your vacation in Amsterdam, one of Europe’s liveliest capitals.
Vineyard underneath the Niederwald Monument, Rudesheim, GermanyRiver through Koblenz GermanyCologne Cathedral, GermanyOld buildings in AmsterdamAmsterdamNurembergWurzburgPrague City and the Charles Bridge at Sunset
Highlights
  • Join a sightseeing tour of Prague and a visit to St. Vitus Cathedral
  • Cruise through the engineering marvel known as the Main-Danube Canal
  • Set off on a walking tour of Kitzingen and see the famous Leaning Tower
  • Admire the many castles and fortress ruins nestled along the Rhine Gorge
Activity Level: Relaxed
Involves minimal physical effort and is typically associated with leisurely activities. Activities are low-intensity or last less than a few hours each day.
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Full Itinerary

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Day 1: Arrive In Prague, Czech Republic

Arrive in Prague and transfer to your hotel. The remainder of the day is free to explore this beautiful city.

Day 2: Prague, Czech Republic

  • 1 Breakfast
Discover Prague on an engaging city tour and find out why it is considered one of Europe’s most attractive cities, with a historic city center that’s recognized as a UNESCO World Heritage Site. See all the key highlights, including the National Museum, Wenceslas Square, the 1,000-year-old Prague Castle and Old Market Square. 

Day 3: Prague | Beer tasting

  • 1 Breakfast
Enjoy a special tasting of the many famous Czech beers. 

Day 4: Prague | Nuremberg, Germany | Embark

Depart Prague after breakfast and drive through the scenic German countryside to Nuremberg for embarkation. Tonight, gather on board your ship for a Welcome Dinner with your fellow passengers. The ship moors in Nuremberg overnight.

Day 5: Nuremberg | Bamberg, Germany

Enjoy breakfast as you cruise through the engineering marvel known as the Main-Danube Canal, which traverses the Alps via 16 locks. Arrive in Bamberg and enjoy a walking tour of this medieval gem, a UNESCO World Heritage Site. Disembark for a guided walking tour and see its cathedral, Old Town Hall and elegant old mansions. Alternatively, you may choose to sample some of Bamberg’s famous smoked beer or enjoy a guided bike tour along the Main River. The ship departs this evening and cruises overnight. 

Day 6: Kitzingen | Würzburg, Germany

This morning, arrive in Kitzingen for a walking tour. See the famous Leaning Tower, built during the 13th century, the Old Main Bridge, Kitzingen Church and the Renaissance Town Hall. Later, the Aulic Council and Wine Queen welcome you to Germany’s oldest wine cellar, where you can taste several different wines and learn about the history of wine production in the region. This afternoon’s guided tour of Würzburg shows you all of the city’s major sights, or you may prefer to visit the Residenz Palace and gardens, a designated UNESCO World Heritage Site. Cruise overnight tonight to Wertheim. 

Day 7: Wertheim, Germany

Welcome to Wertheim, a quaint German town known for its intricate glassworks and charming medieval architecture. You have your choice of one of three excursions today. You have your option of enjoying a guided walking tour of the historic city center, a guided bike tour along the Main River, or a visit to a local bakery for a pretzel tasting. After lunch, the ship cruises towards Mainz.

Day 8: Rudesheim | Koblenz, Germany

This morning, cruise through the picturesque Rhine Gorge, admiring its many castles and fortress ruins and the legendary Lorelei Rock. This afternoon, arrive in the winemaking town of Rüdesheim where you have the option to take one of three excursions: wine tasting with a local vintner, a Gondola Ride above the town to see the Niederwalddenkmal Statue, or a guided bike tour along the Rhine River to one of Germany's best wine regions. Afterwards, you have free time to explore the Drosselgasse, the town’s most famous and charming street, a narrow passage lined with shops and taverns. Later this morning, visit Siegfried’s Mechanical Musical Instrument Museum, home to a remarkable collection of old robotic and self-playing musical instruments. This afternoon, your ship departs for Koblenz and cruises through the Rhine Gorge, the most stunningly beautiful stretch of the river, with hillsides dotted with fairy-tale castles. After arriving in Koblenz this evening, your Cruise Manager takes you on a walking tour through this charming town. The ship moors here overnight. 

Day 9: Koblenz | Cologne, Germany

The ship cruises to Cologne today, where you have an afternoon walking tour of the old part of the city and visit the fabled 13th-century gothic cathedral. Take some free time to explore on your own. The ship departs this evening for Amsterdam. 

Day 10: Amsterdam, The Netherlands

Enjoy a leisurely cruise this morning to Amsterdam, arriving after lunch. You have a guided canal cruise, a city tour of all the top sights, a photo stop at an iconic Dutch windmill and free time to explore this vibrant and colorful city on your own. 

Day 11: Amsterdam | Disembark

  • 1 Breakfast
Your cruise comes to an end as you transfer to the airport for your homeward flight. 

Ship/Hotel

MS Amadante

Dates & Prices

My Preferred Start Date

This itinerary is no longer available. For other trip ideas, please visit Main River Cruises.
Cat E
170 sq. feet. 4 cabins on Piano Deck. Picture window, sitting area, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space. #108-111.
Cat D
170 sq. feet. 7 cabins on Piano Deck. Picture window, sitting area, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space. #101-107.
Cat C
170 sq. feet. 4 cabins on Cello Deck, 4 cabins on Violin Deck. French balcony, sitting area, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space. #227-230 (CD) #329-332 (VD)
Cat B
170 sq. feet. 26 cabins on Cello Deck, 4 cabins on Violin Deck. French balcony, sitting area, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space. #201-226 (CD) #325-328 (VD)
Cat A
170 sq. feet. 28 cabins on Violin Deck. French balcony, sitting area, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space. #305-324.
CatA+
170 sq. feet. 1 cabins on Cello Deck. French balcony, sitting area, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space.#302
Suite
255 sq. feet. 1 cabins on Violin Deck. French balcony, sitting area, bathtub and shower, Infotainment system, safe, hair dryer, bathrobes, A/C, ample closet space. #301,302,304.
Included
  • 10 Breakfasts, 7 Lunches, 7 Dinners
  • 10 Nights Accommodations
  • Accommodations as listed
  • Ground transportation as listed
  • Activities as listed
  • Meals as listed
  • Access to a 24-7 Emergency line while traveling
  • Port Fees
  • Onboard Entertainment 
  • Bottled water replenished daily
  • Personalized service from a highly trained Cruise Manager during both cruise and land programs
  • Beverages: Unlimited fine wine, beer and soft drinks with lunch and dinner.
  • Beverages: Unlimited sparkling wine and fresh juice with breakfast
  • Personal headset for excursions. 
  • Captain’s Welcome Cocktail and Gala Dinner
  • Knowledgeable guides
  • Internet and Wi-Fi access
  • Sip & Sail Daily Cocktail Hour with complimentary wine, beer, spirits and soft drinks
Excluded
  • Gratuities
  • Travel Insurance
  • Personal Expenses
  • Flight costs (please request a quote)
  • Additional excursions during free time
  • Fuel and transportation surcharges (when applicable)
  • Passport and Applicable Visa Expenses
  • Laundry 

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This was my first experience with Adventure Life - and I couldn't have been more pleased with the trip. The guides and local staff in both Buenos Aires and Uruguay were terrific - extremely helpful and accommodating. I really enjoyed meeting the friendly staff in Buenos Aires in person (I left my bags with them for the afternoon).
Karen Snider

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